Clinical Trials

30 enrolled

CNSGastrointestinal

Brain Neoplasms, Esophageal Neoplasms, Stomach Neoplasms

NCT07102329 2026-03-11

ESCAPE

Completed

100,000 enrolled

Barrett Esophagus, Esophageal Neoplasms, Gastroesophageal Reflux, Eosinophilic Esophagitis

NCT07132918 2026-03-11

HEARTS Trial for Thoracic Cancers

60 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Thymoma

NCT06408116 2026-03-10

PEGASUS

30 enrolled

Esophageal Neoplasms

NCT07354295 2026-03-10

Integrating Multimodal AI to Predict Treatment Response and Refine Risk Stratification in Esophageal Cancer （Radiogenomics-Esophagus）

1,500 enrolled

Esophageal Neoplasms

NCT07460596 2026-03-10

Concentrated Complex Plant Dietary Elements for Chemotherapy-Induced Diarrhea

Phase 2 Completed

30 enrolled

Esophageal Neoplasms, Rectal Neoplasms

NCT05706558 2026-03-09

Retrospective Review of Esophageal Cancer at MSKCC

4,000 enrolled

Esophageal Neoplasms

NCT05183126 2026-03-06

Pharmacokinetic Study of Skeletal Muscle Area-based Paclitaxel Infusion in Patients With Cancer

Phase 4 Recruiting

22 enrolled

BreastGastrointestinal

Breast Neoplasms, Esophageal Neoplasms, Stomach Neoplasms

NCT07070466 2026-03-06

Ivonescimab in Comb. With FOLFOX in Advanced HER2 Neg. GEA

40 enrolled

Esophageal Neoplasms, Stomach Neoplasms

NCT00899626 2026-03-05

Gastrointestinal Biomarkers in Tissue and Biological Fluid Samples From Colorectal Cancer Patients

GastrointestinalOther neoplasm

5,000 enrolled

Colonic Neoplasms, Esophageal Neoplasms, Pancreatic Neoplasms, Precancerous Conditions, Stomach Neoplasms, Colorectal Neoplasms, Adenomatous Polyps

NCT04075305 2026-03-05

MOMENTUM

BreastCNSGastrointestinalGenitourinaryHead & NeckThoracic

8,000 enrolled

Urinary Bladder Neoplasms, Brain Neoplasms, Breast Neoplasms, Esophageal Neoplasms, Genital Neoplasms, Female, Head and Neck Neoplasms, Liver Neoplasms, Lung Neoplasms, Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Radiation Injuries, Rectal Neoplasms

NCT07448493 2026-03-04

GASTROBRAIN

Active not recruiting

230 enrolled

CNSGastrointestinal

Brain Neoplasms, Esophageal Neoplasms, Stomach Neoplasms

NCT06452602 2026-02-27

Induction Immunochemotherapy Followed by Concurrent Chemoradiotherapy in Patients With ESCC.

60 enrolled

Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT07307560 2026-02-27

High-Flow Nasal Cannula for Preventing Hypoxia During Sedated Endoscopy in High-Risk Obstructive Sleep Apnea Patients

600 enrolled

Hypoxia, Disease, Esophageal Neoplasms, Stomach Neoplasms, Sleep Apnea, Obstructive

NCT07435454 2026-02-27

Exploratory Clinical Trial of Oral Paclitaxel Plus Radiotherapy in Patients With Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma

22 enrolled

Esophageal Neoplasms

NCT07440212 2026-02-27

Clinical Study on Noninvasive Evaluation of Ivonescimab Antibody Distribution and Expression in Esophageal Cancer Patients by 89Zr-AK112 PET Imaging

Not yet recruiting

50 enrolled

Esophageal Neoplasms

NCT06523374 2026-02-24

Endeavor-1

50 enrolled

Phase 2 Active not recruiting

Adenocarcinoma Of Esophagus, Barrett Esophagus, Esophageal Neoplasms

NCT03174275 2026-02-23

Carboplatin, Nab-Paclitaxel, Durvalumab Before Surgery and Adjuvant Therapy in Head and Neck Squamous Cell Carcinoma

39 enrolled 8 charts

GastrointestinalHead & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Esophageal Neoplasms, Laryngeal Neoplasms, Lip Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT04258813 2026-02-20

ONE TEAM

Phase NA Active not recruiting

313 enrolled

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Cardiovascular Diseases, Colonic Neoplasms, Diabetes Mellitus, Esophageal Neoplasms, Head and Neck Neoplasms, Hypercholesterolemia, Hypertension, Liver Neoplasms, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Endometrial Neoplasms

NCT04354064 2026-02-20

Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

BreastDermatologicGastrointestinalGenitourinaryHead & NeckSarcomaThoracic

100 enrolled

Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Prostatic Neoplasms, Sarcoma, Skin Neoplasms, Urogenital Neoplasms

NCT04907643 2026-02-20

Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes

EndocrineGastrointestinalNET

360 enrolled

Cancer Pain, Anus Neoplasms, Appendiceal Neoplasms, Bile Duct Neoplasms, Biliary Tract Neoplasms, Carcinoid Tumor, Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Liver Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Rectal Neoplasms, Recurrence, Stomach Neoplasms, Neuroendocrine Tumors, Visceral Pain

NCT03896399 2026-02-19

ISCON

Phase NA Completed

22 enrolled

Esophageal Neoplasms

NCT06181656 2026-02-19

Serologic Response to Pneumococcal Vaccination Among Esophageal Cancer Patients With High Grade Lymphopenia After Chemoradiation

80 enrolled

Esophageal Neoplasms, Lymphopenia

NCT06549413 2026-02-19

18F-FSPG PET/CT as a Non-Invasive Imaging Biomarker for Treatment Response to Chemoradiation in Esophageal Cancer

60 enrolled

Esophageal Neoplasms

NCT06346080 2026-02-18

MAGECmultiDiCE

2,200 enrolled

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicOther hematologic neoplasmSarcomaThoracic

Esophageal Neoplasms, Stomach Neoplasms

NCT07410676 2026-02-18

EBNK-ST-001

Phase 1/2 Recruiting

83 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Bronchogenic, Disease, Esophageal Neoplasms, Glioblastoma, Kidney Neoplasms, Leukemia, Liver Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms

NCT07416825 2026-02-18

Inter-Observer Delineation Differences in Esophageal Cancer GTV on MR, CT, and PET/CT Protokol šečerov Ermenc 28dec19

Phase NA Completed

23 enrolled

Esophageal Neoplasms

NCT06346054 2026-02-17

MAGEC

1,000 enrolled

GastrointestinalHead & Neck

Barrett Esophagus, Esophageal Neoplasms, Neoplasms, Stomach Neoplasms

NCT03993353 2026-02-12

Tadalafil and Pembrolizumab in Recurrent or Metastatic Head and Neck Cancer

Phase 2 Completed

7 enrolled 14 charts

Pyridoxine-dependent epilepsy, Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Esophageal Neoplasms, Head and Neck Neoplasms, Mouth Neoplasms, Neoplasm Metastasis, Neoplasms

NCT05787522 2026-02-12

Clinical Validation of AI-Assisted Radiotherapy Contouring Software for Thoracic Organs at Risk

Completed

500 enrolled

BreastGastrointestinalThoracic

Breast Neoplasms, Esophageal Neoplasms, Lung Neoplasms

NCT05775939 2026-02-10

PET/CT Imaging to Evaluate Cardiac Radiation Damage in Patients With Lung or Esophageal Cancer, EUCLID Trial

20 enrolled

GastrointestinalThoracic

Esophageal Neoplasms, Lung Neoplasms

NCT06964568 2026-02-10

CCRT Followed by PD-1 Inhibitor Maintenance Therapy in Locally Advanced ESCC

Phase 3 Recruiting

452 enrolled

BreastGastrointestinalGenitourinaryHead & NeckThoracic

Esophageal Neoplasms

NCT03740256 2026-02-06

VISTA

Phase 1 Recruiting

45 enrolled

Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Breast Neoplasms, Esophageal Neoplasms, Lung Neoplasms, Salivary Gland Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT04359732 2026-02-06

Escape

Phase NA Active not recruiting

121 enrolled

Phase NA Not yet recruiting

Esophageal Neoplasms

NCT07392775 2026-02-06

ALDH2 Genetic Testing in East Asian Community

100 enrolled

Alzheimer Disease, Cardiovascular Diseases, Esophageal Neoplasms, Flushing

NCT04217239 2026-02-05

A Comparison Between Ivor-Lewis and McKeown Minimally Invasive Esophagectomy

Phase NA Completed

272 enrolled

Esophageal Neoplasms

NCT05489250 2026-02-05

PLATON

Terminated

565 enrolled

Esophageal Neoplasms, Gallbladder Neoplasms, Liver Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Cholangiocarcinoma

NCT05334069 2026-02-04

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

BreastDermatologicGastrointestinalGenitourinaryHead & NeckLymphoidMyeloidOther hematologic neoplasmSarcomaThoracic

2,000 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Renal Cell, Esophageal Neoplasms, Lung Neoplasms, Melanoma, Prostatic Neoplasms, Sarcoma, Stomach Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT07375420 2026-02-02

OPTIMUS

50 enrolled

Adenocarcinoma Of Esophagus, Esophageal Neoplasms, Motor Activity

NCT04871412 2026-01-30

POISE

Phase 3 Recruiting

20 enrolled

GastrointestinalThoracic

Psychological Well-Being, Esophageal Neoplasms, Lung Neoplasms, Motor Activity, Stomach Neoplasms

NCT06123338 2026-01-29

A Study of Pembrolizumab With Trastuzumab and Chemotherapy in People With Esophagogastric Cancer

49 enrolled

Phase 2 Not yet recruiting

Esophageal Neoplasms

NCT07376876 2026-01-29

Indocyanine Green-guided Omental Shield Anastomosis for Cervical Esophagogastric Anastomosis in Minimally Invasive McKeown Esophagectomy

73 enrolled