NCT07287202 2025-12-23
Safety, Tolerability, and Pharmacokinetics of SVG103 (Paxalisib) in Focal Cortical Dysplasia Type II (FCD-II), Tuberous Sclerosis Complex (TSC) or Hemimegalencephaly (HME)
Sovargen
Phase 1/2 Not yet recruiting
Clinical Trials
6 trialsNCT06965881 2025-11-21
Study to Evaluate the Pharmacokinetics and Safety Effects Following Coadministration of Carbamazepine or Itraconazole With Radiprodil in Healthy Adults
GRIN Therapeutics, Inc.
Phase 1 Terminated
NCT06975605 2025-11-18
Phase 1, Open-label, Drug-drug Interaction Study to Assess Effect Between Radiprodil and the Co-administered Drugs.
GRIN Therapeutics, Inc.
Phase 1 Completed
NCT06392009 2025-07-03
Astroscape: A Study of Radiprodil on Safety, Tolerability, Pharmacokinetics, and Effect on Seizures and Behavioral Symptoms in Patients With TSC or FCD Type II
GRIN Therapeutics, Inc.
Phase 1/2 Recruiting
NCT04344626 2023-10-10
Use of a Tonometer to Identify Epileptogenic Lesions During Pediatric Epilepsy Surgery
University of California, Los Angeles
Phase NA Withdrawn
NCT02451696 2021-09-01
A Pilot Study To Evaluate The Effects of Everolimus on Brain mTOR Activity and Cortical Hyperexcitability in TSC and FCD
NYU Langone Health
Phase 2 Completed