Clinical Trials

100 enrolled

Phase EARLY_PHASE1 Recruiting

Gastrointestinal Neoplasms

NCT06511037 2026-02-27

PhI Pilot Study Pafolacianine Inject for Intraoperative Imaging on Outcomes of GI Cancer Peritoneal Carcinomatosis

10 enrolled

GastrointestinalGynecologic

Gastrointestinal Neoplasms, Peritoneal Neoplasms

NCT06855524 2026-02-24

Fucoidan for Preventing Chemotherapy-Related Fatigue in Patients With Gastrointestinal or Gynecological Cancer

34 enrolled

Gastrointestinal Neoplasms

NCT04907643 2026-02-20

Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes

EndocrineGastrointestinalNET

360 enrolled

Cancer Pain, Anus Neoplasms, Appendiceal Neoplasms, Bile Duct Neoplasms, Biliary Tract Neoplasms, Carcinoid Tumor, Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Liver Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Rectal Neoplasms, Recurrence, Stomach Neoplasms, Neuroendocrine Tumors, Visceral Pain

NCT07337525 2026-02-18

A First in Human Study of PLT012 in Participants With Solid Tumor Cancers

GastrointestinalGenitourinary

36 enrolled

Urinary Bladder Neoplasms, Gastrointestinal Neoplasms, Liver Neoplasms

NCT07404527 2026-02-13

Bioelectrical Impedance Analysis for Perioperative Fluid Evaluation in Colorectal Cancer Surgery

60 enrolled

Digestive System Neoplasms, Gastrointestinal Neoplasms

NCT07329894 2026-02-12

Safety, Tolerance and Preliminary Efficacy of XH001 Injection Combined With Neoantigen Vaccine-induced Tumor-specific T-cell Injection in Advanced Gastrointestinal Cancer

18 enrolled

Gastrointestinal Neoplasms

NCT07383935 2026-02-11

Stress Ball Use During Chemotherapy in Gastrointestinal Cancer Patients

60 enrolled

Gastrointestinal Neoplasms

NCT05789485 2026-02-06

A Study on the Effects of Exercise on Side Effects From Treatment for Gastrointestinal Cancers

216 enrolled

Gastrointestinal Neoplasms, Motor Activity

NCT06489041 2026-02-02

Evaluating Microarray Pharmacogenetic Testing in Cancer Patients

120 enrolled

Gastrointestinal Neoplasms, Neoplasms

NCT07218926 2026-01-30

A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib Therapy

Phase 3 Recruiting

450 enrolled

GastrointestinalSarcoma

Gastrointestinal Neoplasms, Gastrointestinal Stromal Tumors

NCT07222800 2026-01-30

A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

Phase 3 Recruiting

800 enrolled

Colonic Diseases, Colonic Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasm Metastasis, Neoplasms by Site, Rectal Diseases, Colorectal Neoplasms

NCT05150691 2026-01-28

A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors

BreastGastrointestinalGynecologicThoracic

796 enrolled

Bile Duct Neoplasms, Biliary Tract Neoplasms, Breast Neoplasms, Carcinoma, Carcinoma, Non-Small-Cell Lung, Gastrointestinal Neoplasms, Liver Neoplasms, Neoplasm Metastasis, Neoplasms, Recurrence, Stomach Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT06532877 2026-01-23

Telephone Support in Advanced Gastrointestinal Cancer

488 enrolled

Caregiver Burden, Fatigue, Gastrointestinal Neoplasms

NCT07319364 2026-01-06

A Real-World Study of Fecal Transplants for Cancer Therapy Side Effects

90 enrolled

Gastrointestinal Neoplasms, Drug-Related Side Effects and Adverse Reactions

NCT05066139 2026-01-05

EPODIG-G

144 enrolled

Digestive System Diseases, Gastrointestinal Neoplasms, Neoplasms

NCT06715839 2025-12-31

Target-specific immunoPET Imaging of Digestive System Carcinoma

400 enrolled

Simpson-Golabi-Behmel syndrome, Appendiceal Neoplasms, Bile Duct Neoplasms, Colonic Neoplasms, Digestive System Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Liver Neoplasms, Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT06065371 2025-12-19

Sacituzumab Govitecan in Combination With Capecitabine for Advanced Gastrointestinal Cancers After Progression on Standard Therapy

20 enrolled

Biliary Tract Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT05837767 2025-12-12

A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue

BreastDermatologicGastrointestinalGenitourinarySarcomaThoracic

26 enrolled

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Gastrointestinal Neoplasms, Melanoma, Neoplasm Metastasis, Pancreatic Neoplasms, Sarcoma, Carcinoma, Ductal, Breast, Carcinoma, Lobular

NCT06375187 2025-12-11

KUNLUN-001

BreastGastrointestinalThoracic

18 enrolled

Breast Neoplasms, Gastrointestinal Neoplasms, Lung Neoplasms

NCT04700527 2025-12-10

The Effects of SCFA Supplementation in Subjects Receiving Abdominopelvic RT: A Randomized Controlled Study

122 enrolled

Gastrointestinal Neoplasms, Radiation Injuries

NCT03190941 2025-12-02

Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients

110 enrolled

Colonic Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT06222645 2025-11-18

PPG vs. ICG in Gastrointestinal Resections

200 enrolled

Gastrointestinal Neoplasms, Postoperative Complications, Stomach Neoplasms, Colorectal Neoplasms, Anastomotic Leak

NCT06885034 2025-11-18

A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed

320 enrolled

Gastrointestinal Neoplasms, Colorectal Neoplasms

NCT05489237 2025-11-17

First-in-human Study of IDRX-42 in Participants With Metastatic and/or Unresectable Gastrointestinal Stromal Tumors

278 enrolled

GastrointestinalSarcoma

Digestive System Diseases, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Neoplasm Metastasis, Gastrointestinal Stromal Tumors

NCT05379985 2025-11-12

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

DermatologicGastrointestinalThoracic

754 enrolled

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Gastrointestinal Neoplasms, Intestinal Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplastic Processes, Pancreatic Neoplasms, Thoracic Neoplasms, Colorectal Neoplasms, Carcinoma, Pancreatic Ductal

NCT03800693 2025-11-06

2 Versus 6 Hour Oxaliplatin Infusions in Patients With Gastrointestinal Cancers

60 enrolled

Gastrointestinal Neoplasms

NCT05274048 2025-10-29

Neratinib and Fam-Trastuzumab Deruxtecan in Advanced Gastro-esophageal Cancer Patients

18 enrolled

Gastrointestinal Neoplasms, Stomach Neoplasms

NCT05547919 2025-09-29

GIPSMA

46 enrolled

Gastrointestinal Neoplasms

NCT03745326 2025-09-24

Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients

70 enrolled

Colonic Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT05381038 2025-09-23

Optimizing and Personalising Azacitidine Combination Therapy for Treating Solid Tumours QPOP and CURATE.AI

10 enrolled

BreastGastrointestinal

Breast Neoplasms, Gastrointestinal Neoplasms, Neoplasms

NCT04273061 2025-09-22

CAPTIV-8

BreastDermatologicGastrointestinalHead & NeckSarcomaThoracic

200 enrolled

Breast Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Neoplasms, Unknown Primary, Sarcoma, Skin Neoplasms, Urogenital Neoplasms

NCT06731998 2025-09-18

LapTAP

48 enrolled

Agnosia, Biliary Tract Neoplasms, Gastrointestinal Neoplasms, Liver Neoplasms, Neoplasms, Colorectal Neoplasms

NCT07124351 2025-09-15

Intraoperative Imaging of Gastrointestinal Malignancies Using Pafolacianine (CYTALUX™)

Phase 4 Recruiting

15 enrolled

Appendiceal Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Stomach Neoplasms

NCT05411133 2025-09-04

Treatment of Cabotamig (ARB202) in Advanced Gastrointestinal Cancer Patients

68 enrolled

Adenocarcinoma Of Esophagus, Gastrointestinal Neoplasms, Liver Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Cholangiocarcinoma

NCT06040541 2025-08-28

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

604 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Gastrointestinal Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Colorectal Neoplasms

NCT06908629 2025-08-26

Addressing Social Determinants of Health Among Metro Detroit Cancer Survivors

EndocrineGastrointestinalNETPlasma cell

120 enrolled

Gastrointestinal Neoplasms, Multiple Myeloma, Neoplasms, Neuroendocrine Tumors

NCT06414733 2025-08-24

HER-2 B Cell Peptide Vaccine

42 enrolled

BreastGastrointestinal

Breast Neoplasms, Gastrointestinal Neoplasms

NCT06134687 2025-08-18

Novel Rigidizing Overtube in Colonic Endoscopic Submucosal Dissection

66 enrolled