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Phase 2 × INDUSTRY × Gastrointestinal Stromal Tumors × Clear all

NCT06760819 2026-03-04

panSOHO

Phase 2 Recruiting

BreastGastrointestinalGenitourinaryGynecologicSarcoma

Biliary Tract Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Gastrointestinal Stromal Tumors

NCT07406633 2026-02-12

KQB198 in Combination With Imatinib in Participants With Advanced/Metastatic GIST in 1st Line Setting

Phase 2 Not yet recruiting

GastrointestinalSarcoma

Digestive System Neoplasms, Gastrointestinal Stromal Tumors

NCT04633122 2025-02-10

A Study to Assess DCC-2618 and Sunitinib in Patients With Advanced GIST After Treatment With Imatinib

Phase 2 Completed

108 enrolled 11 charts

GastrointestinalSarcoma

Gastrointestinal Stromal Tumors

NCT01863745 2024-08-19

Nilotinib Roll-over Protocol for Patients in Novartis-sponsored Nilotinib Study and Benefiting From Nilotinib Treatment

Phase 2 Completed

15 enrolled 7 charts

GastrointestinalSarcoma

Neoplasms, Gastrointestinal Stromal Tumors

NCT01294202 2024-08-02

A Study to Investigate the Safety and Efficacy of AT13387, Alone or in Combination With Imatinib, in Patients With GIST

Phase 2 Completed

GastrointestinalSarcoma

Neoplasm Metastasis, Gastrointestinal Stromal Tumors

NCT02232620 2023-11-14

A Study of BBI503 in Adult Patients With Advanced Gastrointestinal Stromal Tumors

Phase 2 Terminated

GastrointestinalSarcoma

Gastrointestinal Stromal Tumors

NCT02034110 2023-08-21

Efficacy and Safety of the Combination Therapy of Dabrafenib and Trametinib in Subjects With BRAF V600E- Mutated Rare Cancers

Phase 2 Completed

206 enrolled 40 charts 2 FDA

CNSEndocrineGastrointestinalHead & NeckOther hematologic neoplasmPlasma cellSarcoma

Nonseminomatous germ cell tumor, Biliary Tract Neoplasms, Glioma, Leukemia, Hairy Cell, Multiple Myeloma, Neoplasms, Gastrointestinal Stromal Tumors, Thyroid Carcinoma, Anaplastic

NCT04106024 2019-09-26

Efficacy and Safety of Anlotinib in Patients With Advanced Gastrointestinal Stromal Tumor After Failure of Imatinib: a Prospective, Single Arm and Multicenter Trial

Phase 2 Unknown

GastrointestinalSarcoma

Gastrointestinal Stromal Tumors

NCT01396148 2019-03-27

A Study of Sunitinib In Young Patients With Advanced Gastrointestinal Stromal Tumor

Phase 2 Completed

6 enrolled 20 charts

GastrointestinalSarcoma

Gastrointestinal Stromal Tumors

NCT01243346 2018-06-28

Study of Crenolanib for the Treatment of Patients With Advanced GIST With the D842-related Mutations and Deletions in the PDGFRA Gene

Phase 2 Completed

GastrointestinalSarcoma

Gastrointestinal Stromal Tumors

NCT01874665 2018-05-18

GIST

Phase 2 Completed

45 enrolled 21 charts

GastrointestinalSarcoma

Gastrointestinal Neoplasms, Gastrointestinal Stromal Tumors

NCT02336724 2018-04-17

A Study of Famitinib in Patients With Gastrointestinal Stromal Tumor

Phase 2 Unknown

GastrointestinalSarcoma

Gastrointestinal Stromal Tumors

NCT00867113 2018-03-14

Five Year Adjuvant Imatinib Mesylate (Gleevec®) in Gastrointestinal Stromal Tumor (GIST)

Phase 2 Completed

91 enrolled 11 charts

GastrointestinalSarcoma

Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Gastrointestinal Stromal Tumors

NCT00455559 2018-02-22

Ph II Study of Perifosine Plus Gleevec for Patients With GIST

Phase 2 Completed

GastrointestinalSarcoma

Gastrointestinal Stromal Tumors

NCT00633295 2017-06-22

Phase II Study Aiming to Evaluate the Efficacy and Safety of Nilotinib Patients With Gastrointestinal Stromal Tumors (GIST) Resistant or Intolerant to Imatinib and or to 2nd Line Tyrosine Kinas (TK) Inhibitor

Phase 2 Completed

GastrointestinalSarcoma

Gastrointestinal Stromal Tumors

NCT01172548 2017-05-31

INV555

Phase 2 Completed

GastrointestinalSarcoma

Recurrence, Gastrointestinal Stromal Tumors

NCT01831726 2017-03-20

SIGNATURE

Phase 2 Completed

80 enrolled 9 charts

DermatologicGastrointestinalGynecologicHead & NeckOther hematologic neoplasmSarcomaThoracic

Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Ovarian Neoplasms, Thyroid Neoplasms, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Gastrointestinal Stromal Tumors

NCT01316263 2017-03-09

A Study of Olaratumab (IMC-3G3) in Previously Treated Participants With Unresectable and/or Metastatic Gastrointestinal Stromal Tumors

Phase 2 Terminated

21 enrolled 24 charts

GastrointestinalSarcoma

Gastrointestinal Stromal Tumors

NCT01110668 2017-02-28

Evaluation of Nilotinib In Patients With Advanced Gastrointestinal Stromal Tumor (GIST)

Phase 2 Completed

GastrointestinalSarcoma

Disease Progression, Gastrointestinal Stromal Tumors

NCT00718562 2017-02-23

Efficacy and Safety of AMN107 in Patients With GastroIntestinal Stromal Tumors (GIST) Who Have Failed Both Imatinib and Sunitinib

Phase 2 Completed

GastrointestinalSarcoma

Gastrointestinal Stromal Tumors

NCT01483014 2016-11-18

CONVERT

Phase 2 Completed

GastrointestinalSarcoma

Gastrointestinal Stromal Tumors

NCT01478373 2016-04-27

Efficacy and Safety of Dovitinib in Patients With Gastrointestinal Stromal Tumors Refractory and/or Intolerant to Imatinib

Phase 2 Completed

39 enrolled 12 charts

GastrointestinalSarcoma

Gastrointestinal Stromal Tumors

NCT00237185 2014-08-19

A Study of the Efficacy and Safety of Imatinib Mesylate in Patients With Unresectable or Metastatic Gastrointestinal Stromal Tumors Expressing C-kit Gene

Phase 2 Completed

148 enrolled 17 charts

GastrointestinalSarcoma

Piebaldism, Gastrointestinal Stromal Tumors

NCT00570635 2013-06-07

A Phase 2 Study of XL820 in Adults With Advanced GIST Resistant to Imatinib and/or Sunitinib

Phase 2 Completed

GastrointestinalSarcoma

Gastrointestinal Neoplasms, Gastrointestinal Stromal Tumors

NCT00385203 2012-07-16

The Biological Activity of Cediranib (AZD2171) in Gastro-Intestinal Stromal Tumours(GIST).

Phase 2 Completed

35 enrolled 13 charts

GastrointestinalSarcoma

Neoplasms, Sarcoma, Gastrointestinal Stromal Tumors

NCT00237172 2012-05-01

Phase II Clinical Study of Imatinib Mesylate in Patients With Malignant Gastrointestinal Stromal Tumors (Extension Study)

Phase 2 Completed

GastrointestinalSarcoma

Gastrointestinal Stromal Tumors

NCT00137449 2009-09-15

Study Of SU011248 Administered On A Continuous Daily Dosing Schedule In Patients With Gastrointestinal Stromal Tumor

Phase 2 Completed

60 enrolled 19 charts

GastrointestinalSarcoma

Gastrointestinal Stromal Tumors