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Recent Start date Enrollment

Terminated × Glioblastoma × abemaciclib × Clear all

Phase

Phase EARLY_PHASE1 1

Status

Recruiting 2 Completed 2 Withdrawn 1 Terminated 1 Active not recruiting 1

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Conditions

Breast Neoplasms 8 Neoplasms 2 Neoplasm Metastasis 2 Triple Negative Breast Neoplasms 1 Thrombocytosis 1 Squamous Cell Carcinoma of Head and Neck 1 Sarcoma 1 Prostatic Neoplasms 1 Primary Myelofibrosis 1 Precursor Cell Lymphoblastic Leukemia-Lymphoma 1 Pancreatic Neoplasms 1 Neoplasms, Squamous Cell 1 Myeloproliferative Disorders 1 Myelodysplastic-Myeloproliferative Diseases 1 Myelodysplastic Syndromes 1 Multiple Myeloma 1 Lymphoma, Non-Hodgkin 1 Leukemia, Myelomonocytic, Chronic 1 Leukemia, Myeloid, Chronic-Phase 1 Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 1 Leukemia, Myeloid, Acute 1 Leukemia, Myeloid, Accelerated Phase 1 Leukemia, Myelogenous, Chronic, BCR-ABL Positive 1 Leukemia, Lymphocytic, Chronic, B-Cell 1 Hodgkin Disease 1 Hematologic Neoplasms 1 Head and Neck Neoplasms 1 Glioblastoma 1 Fibrocystic Breast Disease 1 Colorectal Neoplasms 1

Interventions

Temozolomide 44 Radiotherapy 21 Bevacizumab 21 Radiation 9 Magnetic Resonance Spectroscopy 5 Irinotecan 5 Radiosurgery 4 Nivolumab 4 Lomustine 4 Cilengitide 4 Carmustine 4 Aminolevulinic Acid 4 vocimagene amiretrorepvec 3 vitespin 3 poly ICLC 3 pembrolizumab 3 fluoromisonidazole 3 TPI-287 3 Radiotherapy, Intensity-Modulated 3 Ipilimumab 3 Flucytosine 3 Erlotinib Hydrochloride 3 Dynamic Contrast Enhanced Magnetic Resonance Imaging 3 2,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 3 selinexor 2 sargramostim 2 macitentan 2 carmustine, poliferprosan 20 drug combination 2 cabozantinib 2 Surgical Procedures, Operative 2

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT04074785 2025-08-17

SCCC-06319

University of Texas Southwestern Medical Center

Phase EARLY_PHASE1 Terminated

Brain Neoplasms, Glioblastoma

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