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1 trials

Recent Start date Enrollment

Glioblastoma × binimetinib × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1 CNS 1

Conditions

Melanoma 39 Carcinoma, Non-Small-Cell Lung 15 Lung Neoplasms 10 Colorectal Neoplasms 10 Neoplasm Metastasis 9 Neoplasms 8 Brain Neoplasms 8 Pancreatic Neoplasms 6 Triple Negative Breast Neoplasms 5 Skin Neoplasms 5 Uveal Melanoma 3 Ovarian Neoplasms 3 Gastrointestinal Stromal Tumors 3 Biliary Tract Neoplasms 3 Thyroid Neoplasms 2 Skin Diseases 2 Recurrence 2 Rectal Neoplasms 2 Neurofibromatosis 1 2 Multiple Myeloma 2 Leukemia, Hairy Cell 2 Hereditary Sensory and Autonomic Neuropathies 2 Hematologic Neoplasms 2 Glioma 2 Fallopian Tube Neoplasms 2 Colonic Neoplasms 2 Breast Neoplasms 2 Spinocerebellar Degenerations 1 Solid Tumors Harboring a BRAF V600 Mutation 1 Solid Tumors 1

Interventions

Temozolomide 373 Radiotherapy 187 Bevacizumab 143 Radiation 73 Magnetic Resonance Spectroscopy 67 Lomustine 45 pembrolizumab 38 Surgical Procedures, Operative 37 Irinotecan 37 Carmustine 37 Nivolumab 27 Carboplatin 25 Specimen Handling 24 Radiosurgery 23 Erlotinib Hydrochloride 23 Radiotherapy, Intensity-Modulated 20 Chemotherapy, Adjuvant 20 Aminolevulinic Acid 19 Cyclophosphamide 18 Drug Therapy 17 sargramostim 16 O(6)-benzylguanine 14 Radiotherapy, Conformal 13 Granulocyte-Macrophage Colony-Stimulating Factor 13 Blood Specimen Collection 13 Everolimus 12 temsirolimus 11 Vorinostat 11 Sunitinib 11 Imatinib Mesylate 11

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT03973918 2024-10-31

BRAF

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase 2 Terminated

5 enrolled 15 charts

Astrocytoma, Glioblastoma, Glioma, Gliosarcoma

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