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Clinical Trials

1 trials

Recent Start date Enrollment

Phase 2 × Glioblastoma × binimetinib × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1 CNS 1

Conditions

Melanoma 18 Brain Neoplasms 6 Neoplasms 5 Carcinoma, Non-Small-Cell Lung 5 Pancreatic Neoplasms 3 Neoplasm Metastasis 3 Lung Neoplasms 3 Colorectal Neoplasms 3 Ovarian Neoplasms 2 Multiple Myeloma 2 Leukemia, Hairy Cell 2 Hematologic Neoplasms 2 Uveal Melanoma 1 Triple Negative Breast Neoplasms 1 Thyroid Neoplasms 1 Skin Neoplasms 1 Recurrence 1 Peripheral Nervous System Neoplasms 1 Noonan Syndrome 5 1 Neurofibromatosis 1 1 Neurofibromatoses 1 Neurofibroma, Plexiform 1 Neurofibroma 1 Lymphoma 1 Lymphatic Metastasis 1 Leukemia, Myeloid, Acute 1 Hereditary Sensory and Autonomic Neuropathies 1 Gliosarcoma 1 Glioma 1 Glioblastoma 1

Interventions

Temozolomide 140 Bevacizumab 80 Radiotherapy 69 Magnetic Resonance Spectroscopy 22 Radiation 18 Irinotecan 18 pembrolizumab 17 Lomustine 16 Carmustine 15 Surgical Procedures, Operative 13 Nivolumab 11 Erlotinib Hydrochloride 11 sargramostim 9 Thalidomide 9 Specimen Handling 9 Chemotherapy, Adjuvant 9 Aminolevulinic Acid 9 Carboplatin 8 Cilengitide 7 Sunitinib 6 Immunoglobulin G 6 Etoposide 6 Disulfides 6 Cyclophosphamide 6 antineoplaston AS 2-1 5 antineoplaston A10 5 Radiotherapy, Intensity-Modulated 5 Radiosurgery 5 Metformin 5 Imatinib Mesylate 5

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT03973918 2024-10-31

BRAF

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase 2 Terminated

5 enrolled 15 charts

Astrocytoma, Glioblastoma, Glioma, Gliosarcoma

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