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Interventional × Glioblastoma × talazoparib × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Conditions

Breast Neoplasms 25 Triple Negative Breast Neoplasms 12 Prostatic Neoplasms 11 Ovarian Neoplasms 10 Neoplasms 8 Neoplasm Metastasis 8 Leukemia, Myeloid, Acute 5 Fallopian Tube Neoplasms 5 Small Cell Lung Carcinoma 4 Endometrial Neoplasms 4 Colorectal Neoplasms 4 Carcinoma, Non-Small-Cell Lung 4 Advanced Solid Tumors 4 Pancreatic Neoplasms 3 Stomach Neoplasms 2 Squamous Cell Carcinoma of Head and Neck 2 Sarcoma, Ewing 2 Recurrence 2 Neuroectodermal Tumors, Primitive, Peripheral 2 Carcinoma, Renal Cell 2 Carcinoma, Ovarian Epithelial 2 mCRPC 1 Wilms Tumor 1 Vaginal Neoplasms 1 Uterine Cervical Neoplasms 1 Triple Negative Metastatic Breast Cancer 1 Thrombocythemia, Essential 1 Solid Tumor 1 Sarcoma 1 Rhabdomyosarcoma 1

Interventions

Temozolomide 362 Radiotherapy 181 Bevacizumab 142 Radiation 70 Magnetic Resonance Spectroscopy 60 Lomustine 43 pembrolizumab 37 Irinotecan 37 Carmustine 37 Surgical Procedures, Operative 34 Nivolumab 27 Carboplatin 25 Specimen Handling 23 Radiosurgery 23 Erlotinib Hydrochloride 23 Radiotherapy, Intensity-Modulated 20 Chemotherapy, Adjuvant 20 Aminolevulinic Acid 19 Cyclophosphamide 18 Drug Therapy 17 sargramostim 16 O(6)-benzylguanine 14 Radiotherapy, Conformal 13 Granulocyte-Macrophage Colony-Stimulating Factor 13 Everolimus 12 temsirolimus 11 Vorinostat 11 Sunitinib 11 Imatinib Mesylate 11 Etoposide 11

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT04740190 2025-06-11

TAC-GReD

The University of Hong Kong

Phase 2 Completed

Glioblastoma, Glioma

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