NCT06333899 2026-03-12
Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion
Nationwide Children's Hospital
Phase EARLY_PHASE1 Recruiting
Clinical Trials
65 trialsNCT05076513 2026-03-09
Trial of Niraparib in Participants With Newly-diagnosed Glioblastoma and Recurrent Glioma
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Active not recruiting
NCT05182905 2026-03-09
AZD1390 in Recurrent and Newly Diagnosed WHO Grade 4 Glioma Patients
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Active not recruiting
NCT04391595 2026-03-06
LY3214996 Plus Abemaciclib in Recurrent Glioblastoma Patients
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Completed
NCT07268053 2026-03-06
A Phase 0/1 Clinical Trial With an Expansion Phase of GSK5764227, a B7-H3-Targeted Antibody-Drug Conjugate (ADC), in Patients With Recurrent Grade 4 Glioma and Patients With Brain Metastases
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Recruiting
NCT07284069 2026-03-04
SENIPERA
University of Aarhus
Phase EARLY_PHASE1 Recruiting
NCT07387666 2026-02-06
Imaging Acetadote Metabolism in Glioblastoma
University of Texas Southwestern Medical Center
Phase EARLY_PHASE1 Not yet recruiting
NCT04825275 2026-01-23
Neuro-pharmacological Properties of Repurposed Posaconazole in Glioblastoma: A Phase 0 Clinical Trial
Milton S. Hershey Medical Center
Phase EARLY_PHASE1 Terminated
NCT04656535 2026-01-07
AB154 Combined With AB122 for Recurrent Glioblastoma
Yale University
Phase EARLY_PHASE1 Active not recruiting
NCT04869449 2026-01-07
Neuro-pharmacological Properties of Repurposed Ketoconazole in Glioblastomas
Milton S. Hershey Medical Center
Phase EARLY_PHASE1 Terminated
NCT05091866 2026-01-07
Natural Progesterone for the Treatment of Recurrent Glioblastoma
Emory University
Phase EARLY_PHASE1 Active not recruiting
NCT06645808 2025-12-29
VARTUTRACE
Var2 Pharmaceuticals
Phase EARLY_PHASE1 Recruiting
NCT05423210 2025-12-22
Atezolizumab and Pre-Surgical Brain Radiation Therapy for Glioblastoma Multiforme
Stony Brook University
Phase EARLY_PHASE1 Recruiting
NCT05798507 2025-12-15
Identification of Treatment Concentrations of Defactinib or VS-6766 for the Treatment of Patients With Glioblastoma
Emory University
Phase EARLY_PHASE1 Active not recruiting
NCT06613841 2025-11-28
GBM
Abramson Cancer Center at Penn Medicine
Phase EARLY_PHASE1 Recruiting
NCT07244666 2025-11-24
Safety and Preliminary Efficacy of a Metabolically Armed Chimeric Antigen Receptor T Cell Therapy Targeting EGFRvIII for Recurrent Glioblastoma
Second Affiliated Hospital, School of Medicine, Zhejiang University
Phase EARLY_PHASE1 Not yet recruiting
NCT06831526 2025-11-12
Neoadjuvant Chemoradiotherapy With or Without Concurrent Azeliragon in Patients With Newly Diagnosed Glioblastoma
Washington University School of Medicine
Phase EARLY_PHASE1 Recruiting
NCT04424966 2025-10-24
Infigratinib in Recurrent High-Grade Glioma Patients
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Terminated
NCT04712721 2025-10-10
Study of [68Ga]-FF58 in Patients With Selected Solid Tumors Expected to Overexpress αvβ3 and αvβ5 Integrins.
Novartis
Phase EARLY_PHASE1 Terminated
NCT05023551 2025-09-16
Study of DSP-0390 in Patients With Recurrent High-Grade Glioma
Sumitomo Pharma America, Inc.
Phase EARLY_PHASE1 Active not recruiting
NCT01165632 2025-09-02
Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma
Mayo Clinic
Phase EARLY_PHASE1 Completed
NCT04074785 2025-08-17
SCCC-06319
University of Texas Southwestern Medical Center
Phase EARLY_PHASE1 Terminated
NCT04135807 2025-07-23
Implantable Microdevice In Primary Brain Tumors
Brigham and Women's Hospital
Phase EARLY_PHASE1 Recruiting
NCT07067905 2025-07-16
Clinical Evaluation of [68Ga]Ga-XT771 PET for Diagnosis in Patients With Glioblastoma and Clear Cell Renal Cell Carcinoma
Chinese PLA General Hospital
Phase EARLY_PHASE1 Recruiting
NCT03893487 2025-07-11
PNOC016
University of California, San Francisco
Phase EARLY_PHASE1 Active not recruiting
NCT03834740 2025-05-30
A Phase 0/I Study of Ribociclib (LEE011) in Combination With Everolimus in Preoperative Recurrent High-Grade Glioma Patients Scheduled for Resection
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Completed
NCT05432518 2025-04-25
Pilot Trial for Treatment of Recurrent Glioblastoma
AHS Cancer Control Alberta
Phase EARLY_PHASE1 Recruiting
NCT04614909 2025-02-28
Study of Pamiparib in Newly Diagnosed and rGBM
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Active not recruiting
NCT05773326 2025-02-27
Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Recruiting
NCT06757153 2025-01-03
Safety and Efficacy of NRG-103 Injection in the Treatment of Recurrent Glioblastoma Patients
Zhongnan Hospital
Phase EARLY_PHASE1 Recruiting
NCT03995706 2024-09-04
Neuro/Sacituzumab Govitecan/Breast Brain Metastasis/Glioblastoma/Ph 0
The University of Texas Health Science Center at San Antonio
Phase EARLY_PHASE1 Completed
NCT04937413 2024-06-25
The PCSK9i Inhibitor Evolocumab - a Surgical Trial of Pharamcodynamics and Kinetics Evaluation
Duke University
Phase EARLY_PHASE1 Completed
NCT04221061 2024-06-17
18F-FluorThanatrace (PET/CT) in Glioblastoma
University of Pennsylvania
Phase EARLY_PHASE1 Terminated
NCT05043701 2024-04-03
ISM-GBM
Oslo University Hospital
Phase EARLY_PHASE1 Recruiting
NCT03454295 2024-04-01
Easing Psychosocial Burden for Informal Caregivers
Memorial Sloan Kettering Cancer Center
Phase EARLY_PHASE1 Completed
NCT01383135 2024-01-12
Biodistribution and Safety of the PET Probes [18F]FPRGD2 and [18F]FPPRGD2
Stanford University
Phase EARLY_PHASE1 Completed
NCT01957956 2023-11-18
Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma
Mayo Clinic
Phase EARLY_PHASE1 Completed
NCT05054400 2023-09-01
Study of Laser Interstitial Thermal Therapy (LITT) Treatment Response Assessment With Fluciclovine PET MR
M.D. Anderson Cancer Center
Phase EARLY_PHASE1 Withdrawn
NCT05802693 2023-08-25
A Study to Evaluate the Safety, Tolerance and Initial Efficacy of EGFRvIII CAR-T on Glioblastoma
Beijing Tsinghua Chang Gung Hospital
Phase EARLY_PHASE1 Unknown
NCT03360708 2023-06-28
Vaccine Therapy in Treating Patients With Recurrent Glioblastoma
Mayo Clinic
Phase EARLY_PHASE1 Completed
NCT05017610 2022-12-02
Inducing a Hypothyroxinemic State in Patients With Recurrent Glioblastoma or Gliosarcoma
Emory University
Phase EARLY_PHASE1 Withdrawn
NCT05589961 2022-10-21
Safety and Efficacy of TRPP Therapy in Glioblastoma Multiforme
The Second Hospital of Hebei Medical University
Phase EARLY_PHASE1 Unknown
NCT04776980 2022-09-16
Multimodality MRI and Liquid Biopsy in GBM
Abramson Cancer Center at Penn Medicine
Phase EARLY_PHASE1 Withdrawn
NCT05333588 2022-04-19
The Safety Study of Autologous TILs Therapy for Patients With Glioblastoma Multiforme.
Hebei Senlang Biotechnology Inc., Ltd.
Phase EARLY_PHASE1 Unknown
NCT03291990 2021-11-19
5 Fraction Stereotactic Radiosurgery With Temozolomide for Glioblastoma Multiforme
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Phase EARLY_PHASE1 Completed
NCT03347097 2021-08-25
Adoptive Cell Therapy of Autologous TIL and PD1-TIL Cells for Patients With Glioblastoma Multiforme
Huashan Hospital
Phase EARLY_PHASE1 Unknown
NCT03980249 2021-04-12
Anti-Cancer Effects of Carvedilol With Standard Treatment in Glioblastoma and Response of Peripheral Glioma Circulating Tumor Cells
West Virginia University
Phase EARLY_PHASE1 Withdrawn
NCT02630030 2021-03-26
Phase 0 Analysis of Ixazomib (MLN9708) in Patients With Glioblastoma
Emory University
Phase EARLY_PHASE1 Completed
NCT02605746 2020-12-11
Preoperative Ceritinib (LDK378) in Glioblastoma Multiforme and CNS Metastasis
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Completed
NCT02207010 2020-12-10
A Phase 0 Study of AZD1775 in Recurrent GBM Patients
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Completed