Clinical Trials

52 enrolled

Glioblastoma

NCT03478462 2026-03-18

CLOVER-2

CNSGenitourinaryLymphoidSarcoma

30 enrolled

Diffuse Intrinsic Pontine Glioma, Ependymoma, Glioblastoma, Glioma, Hodgkin Disease, Lymphoma, Lymphoma, Non-Hodgkin, Medulloblastoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT05109728 2026-03-16

A Dose Finding Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination With Standard of Care and in Recurrent Glioblastoma as a Single Agent.

65 enrolled

Phase 4 Active not recruiting

Glioblastoma

NCT03975829 2026-02-13

Pediatric Long-Term Follow-up and Rollover Study

163 enrolled

CNSMyeloid

Astrocytoma, Ganglioneuroma, Glioblastoma, Glioma, Histiocytosis, Langerhans-Cell, Neuroblastoma, Neurofibromatosis 1, Oligodendroglioma, Ganglioglioma, Neurocytoma, Neurofibroma, Plexiform

NCT04485949 2026-02-10

A Phase 2b Clinical Study With a Combination Immunotherapy in Newly Diagnosed Patients With Glioblastoma

93 enrolled

Glioblastoma

NCT03866109 2026-02-09

TEM-GBM

27 enrolled

Glioblastoma

NCT04478279 2026-02-09

A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors

BreastCNSDermatologicGenitourinary

125 enrolled

Brain Neoplasms, Breast Neoplasms, Glioblastoma, Melanoma, Prostatic Neoplasms

NCT05635734 2026-02-05

Azeliragon and Chemoradiotherapy in Newly Diagnosed Glioblastoma

18 enrolled

Glioblastoma

NCT05739942 2026-02-03

Dose Finding Study of [177Lu]Lu-NeoB in Newly Diagnosed Glioblastoma and in Recurrent Glioblastoma

40 enrolled

Glioblastoma

NCT05627323 2026-01-29

CAR T Cells in Patients With MMP2+ Recurrent or Progressive Glioblastoma

42 enrolled

Glioblastoma

NCT04752813 2026-01-26

A Study of BPM31510 With Vitamin K1 in Subjects With Newly Diagnosed Glioblastoma (GB)

50 enrolled

Phase 2/3 Active not recruiting

Glioblastoma

NCT06105619 2026-01-20

A Study of PLB1001 Enteric Capsules in the Treatment of sGBM/IDH Mutant Glioblastoma Patients With the ZM Fusion Gene (FUGEN).

84 enrolled

Glioblastoma

NCT02586857 2026-01-12

A Phase 1b/2, Multicenter, Open-label Study of ACP-196 in Subjects With Recurrent Glioblastoma Multiforme (GBM)

CNSLymphoidOther hematologic neoplasm

24 enrolled 10 charts

Glioblastoma, Leukemia, Lymphocytic, Chronic, B-Cell

NCT04250922 2025-11-20

CLINGLIO

Phase 2/3 Active not recruiting

144 enrolled

Glioblastoma

NCT05275478 2025-11-14

Safety and Tolerability of TNG908 in Patients With MTAP-deleted Solid Tumors

CNSGastrointestinalOther solid neoplasmSarcomaThoracic

192 enrolled

Glioblastoma, Mesothelioma, Sarcoma, Cholangiocarcinoma, Neurofibrosarcoma

NCT06521567 2025-11-12

A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer

CNSDermatologicGastrointestinalLymphoidSarcoma

83 enrolled

Fibrolamellar hepatocellular carcinoma, Diffuse Intrinsic Pontine Glioma, Ependymoma, Glioblastoma, Carcinoma, Hepatocellular, Hodgkin Disease, Melanoma, Rhabdomyosarcoma, Osteosarcoma, Hepatoblastoma

NCT02381886 2025-11-10

A Study of IDH305 in Patients With Advanced Malignancies That Harbor IDH1R132 Mutations

CNSGastrointestinalMyeloidOther hematologic neoplasm

166 enrolled

Astrocytoma, Glioblastoma, Glioma, Leukemia, Myelodysplastic Syndromes, Oligodendroglioma, Leukemia, Myeloid, Acute, Cholangiocarcinoma

NCT05902169 2025-11-10

SONOBIRD

Phase 3 Active not recruiting

560 enrolled

Glioblastoma

NCT03862430 2025-10-09

RESTORE

87 enrolled

Phase EARLY_PHASE1 Active not recruiting

Glioblastoma

NCT05023551 2025-09-16

Study of DSP-0390 in Patients With Recurrent High-Grade Glioma

39 enrolled

Phase 4 Active not recruiting

Brain Neoplasms, Glioblastoma, Glioma

NCT05342883 2025-09-05

GESTALT

61 enrolled

Glioblastoma, Glioma, Neoplasms

NCT04587830 2025-08-26

GBM

100 enrolled

Glioblastoma

NCT04910022 2025-08-19

Ph I/II Study of NMS-03305293+TMZ in Adult Patients With Recurrent Glioblastoma

150 enrolled

Glioblastoma

NCT05222802 2025-08-17

A Study to Evaluate ERAS-801 in Patients With Recurrent Glioblastoma (THUNDERBBOLT-1)

52 enrolled

Phase NA Active not recruiting

Glioblastoma

NCT04471844 2025-08-07

EF-32

981 enrolled

Glioblastoma

NCT02974738 2025-07-10

MK-6482-001

120 enrolled

CNSGenitourinary

Carcinoma, Renal Cell, Glioblastoma, Kidney Neoplasms, Neoplasm Metastasis

NCT04521686 2025-06-27

Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 Mutations

BreastCNSDermatologicGastrointestinalGenitourinaryHead & NeckSarcoma

200 enrolled

Breast Neoplasms, Chondrosarcoma, Colonic Neoplasms, Glioblastoma, Glioma, Melanoma, Prostatic Neoplasms, Thyroid Neoplasms, Central Nervous System Neoplasms, Cholangiocarcinoma

NCT03897491 2025-05-14

PD L 506 for Stereotactic Interstitial Photodynamic Therapy of Newly Diagnosed Supratentorial IDH Wild-type Glioblastoma

20 enrolled

Glioblastoma

NCT04762069 2025-05-04

A Study of Berubicin in Adult Subjects With Recurrent Glioblastoma Multiforme

210 enrolled

Brain Neoplasms, Glioblastoma

NCT05664243 2025-05-01

A Phase 1b / 2 Drug Resistant Immunotherapy With Activated, Gene Modified Allogeneic or Autologous γδ T Cells (DeltEx) in Combination With Maintenance Temozolomide in Subjects With Recurrent or Newly Diagnosed Glioblastoma

4 enrolled

Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neoplasms by Site, Central Nervous System Neoplasms

NCT01903330 2025-03-05

ERC1671/GM-CSF/Cyclophosphamide for the Treatment of Glioblastoma Multiforme

84 enrolled

CNSSarcoma

Glioblastoma, Gliosarcoma

NCT05698199 2024-12-06

Study to Evaluate the Safety, Tolerability, Immunogenicity and Preliminary Efficacy of ITI-1001 In Patients With Newly Diagnosed Glioblastoma (GBM)

10 enrolled

Glioblastoma

NCT05561374 2024-11-29

Study of Safety and Pharmacokinetic Properties of Oral OKN-007 in Patients with Recurrent High-Grade Glioma

16 enrolled

Phase 3 Active not recruiting

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT05118776 2024-10-31

Study to Evaluate the Safety and Efficacy of ASC40 Tablets in Combination With Bevacizumab in Subjects With rGBM

136 enrolled

Glioblastoma

NCT04913337 2024-10-02

Study of NGM707 As Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

179 enrolled

Squamous Cell Carcinoma of Head and Neck, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Glioblastoma, Melanoma, Mesothelioma, Ovarian Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT05986851 2024-09-05

Azeliragon in MGMT Unmethylated Glioblastoma

30 enrolled