Clinical Trials

180 enrolled

Glioblastoma

NCT06641908 2026-02-18

Anti-GD2 ADC M3554 in Advanced Solid Tumors

52 enrolled

CNSSarcoma

Glioblastoma, Sarcoma

NCT06061809 2026-02-12

N-803 and PD-L1 t-haNK Combined With Bevacizumab for Recurrent or Progressive Glioblastoma

34 enrolled

Glioblastoma

NCT07042620 2026-02-10

A Study to Test a New Fluid to Improve the Quality of Images Obtained by Using Sound Waves (Ultrasound) During Surgery

Phase NA Recruiting

15 enrolled

Glioblastoma, Glioma

NCT07225621 2026-02-05

Adjuvant Temozolomide ± 5-Aminolevulinic Acid + Low Intensity Diffuse Ultrasound Sonodynamic Therapy System for Newly Diagnosed Glioblastoma

103 enrolled

Glioblastoma

NCT06810544 2026-02-02

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

191 enrolled

CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Glioblastoma, Glioma, Lung Neoplasms

NCT05450744 2026-01-21

IPAX-2

12 enrolled

Glioblastoma, Neoplasms

NCT05283330 2026-01-15

Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

BreastCNSGastrointestinalGynecologicThoracic

48 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Colonic Neoplasms, Glioblastoma

NCT06717295 2026-01-02

CCANED-CIPHER

Recruiting

6,000 enrolled

CNSGastrointestinalGenitourinaryGynecologicThoracic

Pancreatic cancer, adult, Carcinoma, Non-Small-Cell Lung, Glioblastoma, Carcinoma, Hepatocellular, Lung Neoplasms, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms

NCT06645808 2025-12-29

VARTUTRACE

Phase EARLY_PHASE1 Recruiting

32 enrolled

BreastCNSGastrointestinalGenitourinaryHead & NeckSarcomaThoracic

Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Breast Neoplasms, Chondrosarcoma, Colonic Neoplasms, Esophageal Neoplasms, Glioblastoma, Lung Neoplasms, Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Sarcoma, Osteosarcoma, Stomach Neoplasms

NCT03423628 2025-12-22

A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer

180 enrolled

Brain Neoplasms, Glioblastoma, Inhibition, Psychological, Meningeal Neoplasms, Hereditary Sensory and Autonomic Neuropathies

NCT04541082 2025-12-18

Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

102 enrolled

CNSSarcoma

Typical Teratoid Rhabdoid Tumor, Astrocytoma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Oligodendroglioma, Pinealoma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma

NCT06910306 2025-12-05

A Study to Assess the Feasibility and Safety of Intratumoral Diffusing Alpha Emitters for the Treatment of Recurrent Glioblastoma

Phase NA Recruiting

10 enrolled

Glioblastoma, Glioma

NCT04094610 2025-11-19

A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

CNSLymphoidPlasma cellSarcoma

75 enrolled

Glioblastoma, Glioma, Granuloma, Plasma Cell, Lymphoma, Neoplasm Metastasis, Sarcoma, Lymphoma, Large-Cell, Anaplastic, Solitary Fibrous Tumors

NCT06011109 2025-10-02

Treatment of Patients With Recurrent High-Grade Glioma With APG-157 and Bevacizumab

30 enrolled

Glioblastoma, Glioma

NCT05941507 2025-09-24

A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors

BreastCNSGastrointestinalGynecologicHead & NeckThoracic

300 enrolled

Squamous Cell Carcinoma of Head and Neck, Anus Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Glioblastoma, Head and Neck Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Salivary Gland Neoplasms, Stomach Neoplasms, Endometrial Neoplasms

NCT05736406 2025-09-11

A Dose-escalation Clinical Study of Intraoperative Photodynamic Therapy of Glioblastoma

12 enrolled

Glioblastoma, Glioma

NCT06533163 2025-07-14

OMX-EFS-01

Phase NA Recruiting

40 enrolled

Glioblastoma

NCT03175224 2025-06-27

SPARTA

CNSGastrointestinalGenitourinaryHead & NeckThoracic

497 enrolled

Brain Neoplasms, Colonic Neoplasms, Glioblastoma, Kidney Neoplasms, Lung Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Thyroid Neoplasms

NCT05226494 2025-06-04

Safety and Tolerability of Fb-PMT in Recurrent Glioblastoma

34 enrolled

Glioblastoma, Glioma

NCT06902350 2025-05-25

Safety, Pharmacokinetics and Preliminary Efficacy of CS231295 in Advanced Solid Tumors

102 enrolled

CNSThoracic

Glioblastoma, Neoplasms, Small Cell Lung Carcinoma

NCT06598787 2025-05-07

A Study of BL-B01D1 in Patients With Recurrent Glioblastoma

20 enrolled

Glioblastoma

NCT06924099 2025-04-11

TIGER France

Recruiting

430 enrolled

Glioblastoma

NCT05460507 2025-03-30

Safety & Efficacy/Tolerability of Rhenium-186 NanoLiposomes (186RNL) for Patients Who Received a Prior 186RNL Treatment

40 enrolled

Brain Neoplasms, Glioblastoma, Glioma

NCT01906385 2025-03-26

Maximum Tolerated Dose, Safety, and Efficacy of Rhenium Nanoliposomes in Recurrent Glioma (ReSPECT)

55 enrolled

Brain Neoplasms, Glioblastoma, Glioma

NCT06161974 2025-02-21

Study of Olutasidenib and Temozolomide in HGG

60 enrolled

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Spinal Cord Neoplasms

NCT06336291 2025-01-24

GLIOSTELLA

90 enrolled

Glioblastoma

NCT05768919 2024-11-29

Study of Liposomal Curcumin in Combination With RT and TMZ in Patients With Newly Diagnosed High-Grade Gliomas

30 enrolled

Glioblastoma

NCT06496971 2024-11-14

A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastin® Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patients

Phase 3 Recruiting

32 enrolled

Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neoplasms, Nerve Tissue

NCT06650605 2024-10-21

CITADEL-123

67 enrolled

Glioblastoma

NCT06595186 2024-09-19

JK-1201I Combined with Adjuvant Temozolomide in Patients with Newly Diagnosed Glioblastoma Multiforme (GBM)

25 enrolled

Glioblastoma

NCT06353360 2024-08-09

TTField in Combination With Temozolomide and Tislelizumab in The Treatment of Newly Diagnosed Glioblastoma.

30 enrolled

Glioblastoma

NCT04573192 2024-04-08

GLIOSTAR

142 enrolled

Glioblastoma

NCT04443010 2023-10-10

GLIOSUN

226 enrolled