Clinical Trials Browser

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT02359565 2026-03-18

Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma

Familial ependymoma, Turcot syndrome, Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Colorectal Neoplasms, Hereditary Nonpolyposis, Ependymoma, Glioma, Medulloblastoma

NCT03478462 2026-03-18

CLOVER-2

Phase 1 Active not recruiting

30 enrolled

CNSGenitourinaryLymphoidSarcoma

Diffuse Intrinsic Pontine Glioma, Ependymoma, Glioblastoma, Glioma, Hodgkin Disease, Lymphoma, Lymphoma, Non-Hodgkin, Medulloblastoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

Clinical Trials

Vorinostat and Temozolomide in Treating Patients With Malignant Gliomas

Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma

CLOVER-2

Novel Targeted Radiotherapy in Pediatric Patients With Inoperable Relapsed or Refractory HGG

DUAL-CAR-NK-GB

A Study to Test How Well Different Doses of BI 764532 Are Tolerated by People With a Tumour in the Brain That is Positive for DLL3

Hypofractionation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma

CILENT

Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)

A Study on the Novel Oncolytic Virus Combined With PD-1 Inhibitor in the Treatment of Recurrent High-grade Glioma

PNOC017

IMPACT

A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma

PNOC020

INSIGHT MRL

D2C7 for Adult Patients With Recurrent Malignant Glioma

A Phase I Study of FZ-AD005 in Patients With High-Grade Glioma (HGG)

MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma

CUE-102 in Recurrent Glioblastoma

rQNestin

A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors

Abemaciclib Neuropharmacokinetics of Diffuse Midline Glioma Using Intratumoral Microdialysis

Fluorescence-Guided Imaging of Brain Tumors: A Safety Study Using SBK2-ICG

Engineered HSV-1 M032 for the Treatment of Children and Adults With Newly Diagnosed Diffuse Midline Glioma After Standard of Care Radiation

Ruxolitinib With Radiation and Temozolomide for Grade III Gliomas and Glioblastoma

Study of Orally Administered AG-881 in Patients With Advanced Solid Tumors, Including Gliomas, With an IDH1 and/or IDH2 Mutation

Study of AG-120 and AG-881 in Subjects With Low Grade Glioma

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

Prospective Surgical Study on the Pattern of Electrical Activity in High Grade Glioma as a Predictor of Progression

Phase I Trial of pH Resections of GBM at VA

Zr-89 Crefmirlimab Berdoxam and Immuno-Positron Emission Tomography for the Imaging of Patients With Resectable Brain Tumors

Study of DS-1001b in Patients With Gene IDH1-Mutated Gliomas

Memory-Enriched T Cells in Treating Patients With Recurrent or Refractory Grade III-IV Glioma

CARv3-TEAM-E T Cells in Glioblastoma

A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.

ACTION

FUS Etoposide for DMG

Tumor Hypoxia and Proliferation in Patients With High-Grade Glioma

Re-Administration of C134 in Patients With Recurrent GBM (C134-HSV-1)

A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors

GABRIEL

Safety and Efficacy Study of TX103 CAR-T Cell Therapy for Recurrent or Progressive Grade 4 Glioma.

Concurrent Azeliragon With Craniospinal Irradiation

A Phase I Clinical Trial of a mRNA Vaccine for Recurrent or Progressive High-grade Glioma

GLIOSPECT