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Recent Start date Enrollment

Has results × Glioma × binimetinib × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1 CNS 1

Conditions

Melanoma 12 Colorectal Neoplasms 6 Carcinoma, Non-Small-Cell Lung 6 Neoplasm Metastasis 5 Neoplasms 4 Lung Neoplasms 4 Brain Neoplasms 4 Skin Neoplasms 2 Skin Diseases 2 Hematologic Neoplasms 2 Uveal Melanoma 1 Triple Negative Breast Neoplasms 1 Spinocerebellar Degenerations 1 Solid Tumors Harboring a BRAF V600 Mutation 1 Soft Tissue Neoplasms 1 Peripheral Nervous System Neoplasms 1 Parkinson Disease 4, Autosomal Dominant Lewy Body 1 Pancreatic Neoplasms 1 Noonan Syndrome 5 1 Neurofibromatosis 1 1 Neurofibromatoses 1 Neurofibroma, Plexiform 1 Neurofibroma 1 Multiple Myeloma 1 Lymphoma 1 Lymphatic Metastasis 1 Low-grade Serous Ovarian Cancer 1 Leukemia, Myeloid, Acute 1 Hereditary Sensory and Autonomic Neuropathies 1 Gliosarcoma 1

Interventions

Temozolomide 42 Bevacizumab 38 Radiotherapy 16 Magnetic Resonance Spectroscopy 12 Irinotecan 11 Nivolumab 7 Everolimus 6 Radiation 5 Carboplatin 5 poly ICLC 4 pembrolizumab 4 X-Rays 4 Phantoms, Imaging 4 Erlotinib Hydrochloride 4 Carmustine 4 ribociclib 3 fluorodopa F 18 3 Vorinostat 3 Specimen Handling 3 Radiotherapy, Intensity-Modulated 3 Radiosurgery 3 Nuclear Medicine Department, Hospital 3 Modafinil 3 Lomustine 3 trametinib 2 selinexor 2 plerixafor 2 perampanel 2 palbociclib 2 lenvatinib 2

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT03973918 2024-10-31

BRAF

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase 2 Terminated

5 enrolled 15 charts

Astrocytoma, Glioblastoma, Glioma, Gliosarcoma

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