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Recent Start date Enrollment

Terminated × Glioma × binimetinib × Clear all

Phase

Status

Terminated 1 Recruiting 1

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1 CNS 1

Conditions

Melanoma 8 Carcinoma, Non-Small-Cell Lung 5 Neoplasms 3 Lung Neoplasms 2 Brain Neoplasms 2 Uveal Melanoma 1 Skin Neoplasms 1 Pancreatic Neoplasms 1 Neurofibromatosis 1 1 Neoplasm Metastasis 1 Lymphatic Metastasis 1 Low-grade Serous Ovarian Cancer 1 Leukemia, Myeloid, Chronic-Phase 1 Leukemia 1 Hereditary Sensory and Autonomic Neuropathies 1 Gliosarcoma 1 Glioma 1 Glioblastoma 1 Disease Progression 1 Colorectal Neoplasms 1 Central Nervous System Neoplasms 1 Brain Diseases 1 Blast Crisis 1 Astrocytoma 1 Anatomic Stage IV Breast Cancer AJCC v8 1

Interventions

Temozolomide 21 Bevacizumab 10 Radiotherapy 5 Irinotecan 5 Carmustine 4 Topotecan 3 Magnetic Resonance Spectroscopy 3 Magnetic Resonance Imaging 3 Carboplatin 3 Aminolevulinic Acid 3 ribociclib 2 poly ICLC 2 fluoromisonidazole 2 fluorodopa F 18 2 carmustine, poliferprosan 20 drug combination 2 cabozantinib 2 TIC10 compound 2 Surgical Procedures, Operative 2 Standard of Care 2 Re-Irradiation 2 Radiotherapy, Intensity-Modulated 2 Radiosurgery 2 Panobinostat 2 O(6)-benzylguanine 2 Melphalan 2 Lomustine 2 Lacosamide 2 Filgrastim 2 Erlotinib Hydrochloride 2 Dynamic Contrast Enhanced Magnetic Resonance Imaging 2

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT03973918 2024-10-31

BRAF

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase 2 Terminated

5 enrolled 15 charts

Astrocytoma, Glioblastoma, Glioma, Gliosarcoma

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