Clinical Trials

29 enrolled

Glioma, Recurrence, Central Nervous System Neoplasms

NCT01478178 2025-08-29

Safety Study of VAL-083 in Patients With Recurrent Malignant Glioma

55 enrolled

Brain Neoplasms, Glioblastoma, Glioma

NCT02655601 2025-06-08

BMX-HGG

177 enrolled 34 charts

Astrocytoma, Glioblastoma, Glioma

NCT02311582 2025-05-29

MK-3475 in Combination With MRI-guided Laser Ablation in Recurrent Malignant Gliomas

55 enrolled 14 charts

Glioma

NCT02960230 2025-01-22

H3.3K27M Peptide Vaccine With Nivolumab for Children With Newly Diagnosed DIPG and Other Gliomas

50 enrolled 12 charts

Diffuse Intrinsic Pontine Glioma, Glioma

NCT04267146 2024-12-02

NIVOGLIO

41 enrolled

Glioma

NCT03234595 2024-09-19

A Phase I/IIa Study of Cerebraca Wafer Plus Adjuvant Temozolomide (TMZ) in Patients With Recurrent High Grade Glioma

22 enrolled

Astrocytoma, Glioblastoma, Glioma

NCT03879512 2024-09-19

Autologous Dendritic Cells, Metronomic Cyclophosphamide and Checkpoint Blockade in Children With Relapsed HGG

24 enrolled

Astrocytoma, Glioma

NCT04497142 2024-08-05

Effect of Perampanel on Peritumoral Hyperexcitability in HGG

12 enrolled 8 charts

Glioma, Seizures

NCT01837862 2024-07-05

A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas

36 enrolled

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Glioblastoma, Glioma, Gliosarcoma, Optic Nerve Glioma

NCT02490800 2024-06-26

Phase 1/2a Study of Oral BAL101553 in Adult Patients With Solid Tumors or Glioblastoma or High-grade Glioma

72 enrolled 30 charts

Glioblastoma, Glioma, Neoplasms

NCT02052648 2024-03-27

Study of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain Tumors

160 enrolled 21 charts

Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

NCT01128218 2023-11-30

A Study of the Specificity and Sensitivity of 5- Aminolevulinic Acid (ALA) Fluorescence in Malignant Brain Tumors

33 enrolled 15 charts

Brain Neoplasms, Glioblastoma, Glioma

NCT02315534 2023-11-15

A Study of BBI608 in Combination With Temozolomide in Adult Patients With Recurrent or Progressed Glioblastoma

34 enrolled 18 charts

Glioblastoma, Glioma

NCT03245151 2023-08-30

Study of Lenvatinib in Combination With Everolimus in Recurrent and Refractory Pediatric Solid Tumors, Including Central Nervous System Tumors

64 enrolled 29 charts

Glioma, Recurrence, Rhabdomyosarcoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral

NCT02661282 2023-06-18

Autologous CMV-Specific Cytotoxic T Cells and Temozolomide in Treating Patients With Glioblastoma

65 enrolled 21 charts

Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

NCT01081223 2023-06-01

Phase I/II Study To Test The Safety and Efficacy of TVI-Brain-1 As A Treatment For Recurrent Grade IV Glioma

12 enrolled 11 charts

Astrocytoma, Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, Glioblastoma, Glioma, Neoplasms, Nervous System Diseases, Nervous System Neoplasms, Central Nervous System Neoplasms

NCT01792310 2023-02-21

A Phase 1/2A Study of LAM561 in Adult Patients With Advanced Solid Tumours

54 enrolled

Glioma

NCT02330562 2022-06-08

Stage 1: Marizomib + Bevacizumab in WHO Gr IV GBM; Stage 2: Marizomib Alone; Stage 3: Combination of Marizomib and Bevacizumab

121 enrolled 27 charts

Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

NCT02750891 2022-04-12

A Study of DSP-7888 in Pediatric Patients With Relapsed or Refractory High Grade Gliomas

18 enrolled

Diffuse Intrinsic Pontine Glioma, Glioblastoma, Glioma

NCT00303849 2022-03-17

Carboplatin, Melphalan, Etoposide Phosphate, Mannitol, and Sodium Thiosulfate in Treating Patients With Previously Treated Brain Tumors

33 enrolled

Astrocytoma, Glioma, Oligodendroglioma

NCT02273739 2021-02-23

Study of Orally Administered Enasidenib (AG-221) in Adults With Advanced Solid Tumors, Including Glioma, or Angioimmunoblastic T-cell Lymphoma, With an IDH2 Mutation

CNSGastrointestinalSarcoma

21 enrolled 33 charts

Chondrosarcoma, Glioma, Immunoblastic Lymphadenopathy, Cholangiocarcinoma

NCT01024907 2020-12-10

Proton Beam Radiation Therapy in Treating Patients With Low Grade Gliomas

23 enrolled

Astrocytoma, Brain Neoplasms, Ependymoma, Glioma, Oligodendroglioma, Pinealoma

NCT02590263 2020-09-03

Study Evaluating ABT-414 in Japanese Subjects With Malignant Glioma

53 enrolled

CNSLymphoid

Glioblastoma, Glioma, Lymphoma, Follicular

NCT00049127 2019-10-21

Imatinib Mesylate in Treating Patients With Recurrent Brain Tumor

64 enrolled 11 charts

Brain Neoplasms, Glioma, Oligodendroglioma

NCT01580969 2019-08-16

RAMBO

22 enrolled 18 charts

Glioma

NCT00038441 2018-10-31

Phase I Trial of Intramural Injection of DTI-015 for Recurrent Malignant Gliomas

39 enrolled

Brain Neoplasms, Glioma

NCT01977677 2018-10-23

Plerixafor After Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed High Grade Glioma

30 enrolled 11 charts

Glioblastoma, Glioma, Medulloblastoma, Pinealoma, Neuroectodermal Tumors, Primitive, Gliosarcoma

NCT02253212 2018-10-12

SONOCLOUD

27 enrolled

Brain Neoplasms, Glioblastoma, Glioma

NCT01266031 2018-07-31

Phase I/II Adaptive Randomized Trial of Bevacizumab Versus Bevacizumab Plus Vorinostat in Adults With Recurrent Glioblastoma

96 enrolled 15 charts

Glioblastoma, Glioma

NCT00003616 2018-06-27

Irinotecan in Treating Patients With Progressive or Recurrent Malignant Glioma

Astrocytoma, Brain Neoplasms, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00004868 2018-06-27

SU5416 in Treating Patients With Recurrent Astrocytoma or Mixed Glioma That Has Not Responded to Radiation Therapy

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Meningioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00010049 2018-06-27

Imatinib Mesylate in Treating Patients With Recurrent Malignant Glioma or Meningioma

105 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Meningioma, Oligodendroglioma, Central Nervous System Neoplasms, Glioma, Subependymal, Gliosarcoma

NCT00022724 2018-06-26

CCI-779 in Treating Patients With Malignant Glioma

49 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT01648348 2018-05-23

Bevacizumab With or Without Anti-Endoglin Monoclonal Antibody TRC105 in Treating Patients With Recurrent Glioblastoma Multiforme

116 enrolled 17 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT00766753 2018-02-07

Vaccination-Dendritic Cells With Peptides for Recurrent Malignant Gliomas

22 enrolled 8 charts

Glioma

NCT01465347 2017-07-14

Safety and Efficacy of Trans Sodium Crocetinate (TSC) With Radiation and Temozolomide in Newly Diagnosed Glioblastoma

59 enrolled 10 charts

Brain Neoplasms, Glioblastoma, Glioma

NCT01026493 2017-07-02

Veliparib and Temozolomide in Treating Patients With Recurrent Glioblastoma

257 enrolled 16 charts

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00859222 2017-03-14

LBH589 and Bevacizumab in Patients With Recurrent High Grade Glioma

51 enrolled 18 charts

Glioma

NCT01220271 2017-02-16

A Study Combining LY2157299 With Temozolomide-based Radiochemotherapy in Patients With Newly Diagnosed Malignant Glioma

75 enrolled

Glioblastoma, Glioma

NCT02104882 2016-10-17

INTRAGO-Intraoperative Radiotherapy for Glioblastoma - a Phase I/II Study

12 enrolled

Glioblastoma, Glioma

NCT00250211 2016-02-24

Magnetic Resonance Spectroscopic Imaging (MRS) and Tumor Perfusion of Human Glioblastoma Treated With Concurrent Radiation Therapy and Temozolomide

26 enrolled

Glioblastoma, Glioma

NCT00112736 2015-06-15

Erlotinib and Temsirolimus in Treating Patients With Recurrent Malignant Glioma

69 enrolled 12 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT01386580 2015-01-22

An Open-label, Phase I/IIa, Dose Escalating Study of 2B3-101 in Patients With Solid Tumors and Brain Metastases or Recurrent Malignant Glioma.

BreastCNSDermatologicThoracic

84 enrolled

Brain Diseases, Brain Neoplasms, Breast Neoplasms, Central Nervous System Diseases, Glioma, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Neoplasms by Site, Neoplastic Processes, Nervous System Diseases, Nervous System Neoplasms, Pathologic Processes, Central Nervous System Neoplasms

NCT00024570 2014-11-14

Interstitial Infusion of IL13-PE38QQR Cytotoxin in Recurrent Malignant Glioma

60 enrolled

Astrocytoma, Glioblastoma, Glioma, Recurrence

NCT00003461 2014-08-21

Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Tumors

Astrocytoma, Brain Neoplasms, Craniopharyngioma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neoplasm Metastasis, Neuroblastoma, Oligodendroglioma, Pinealoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00002752 2014-07-16

Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Cancers

Familial ependymoma, Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Neoplasm Metastasis, Oligodendroglioma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Gliosarcoma

NCT00919737 2013-10-30

Study of NPC-08 is to Treat for Newly-Diagnosed Malignant Glioma and Recurrent Glioblastoma Multiforme

24 enrolled

Glioma

NCT00006268 2013-06-24

Immunotoxin Therapy in Treating Patients With Malignant Glioma