NCT04573140 2026-03-19
PNOC020
University of Florida
Phase 1 Active not recruiting
Clinical Trials
198 trialsNCT07481721 2026-03-19
APIC-RG
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Phase 1 Not yet recruiting
NCT02115074 2026-03-18
FLUVABREX
Centre Oscar Lambret
Phase 1 Completed
NCT04943848 2026-03-17
rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG
Ann & Robert H Lurie Children's Hospital of Chicago
Phase 1 Recruiting
NCT01165333 2026-03-16
CILENT
Centre Oscar Lambret
Phase 1 Completed
NCT04485559 2026-03-16
Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)
University of California, San Francisco
Phase 1 Recruiting
NCT03749187 2026-03-13
PNOC017
University of California, San Francisco
Phase 1 Active not recruiting
NCT06946680 2026-03-13
IMPACT
University of Florida
Phase 1 Active not recruiting
NCT07457307 2026-03-09
INSIGHT MRL
NYU Langone Health
Phase 1 Not yet recruiting
NCT02303678 2026-03-06
D2C7 for Adult Patients With Recurrent Malignant Glioma
Duke University
Phase 1 Completed
NCT03896568 2026-03-05
MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma
M.D. Anderson Cancer Center
Phase 1 Recruiting
NCT06917885 2026-03-05
CUE-102 in Recurrent Glioblastoma
Dana-Farber Cancer Institute
Phase 1 Recruiting
NCT03152318 2026-03-04
rQNestin
Dana-Farber Cancer Institute
Phase 1 Active not recruiting
NCT07438860 2026-02-27
Fluorescence-Guided Imaging of Brain Tumors: A Safety Study Using SBK2-ICG
Case Comprehensive Cancer Center
Phase 1 Not yet recruiting
NCT07076498 2026-02-25
Engineered HSV-1 M032 for the Treatment of Children and Adults With Newly Diagnosed Diffuse Midline Glioma After Standard of Care Radiation
M.D. Anderson Cancer Center
Phase 1 Not yet recruiting
NCT03514069 2026-02-19
Ruxolitinib With Radiation and Temozolomide for Grade III Gliomas and Glioblastoma
Case Comprehensive Cancer Center
Phase 1 Active not recruiting
NCT03911388 2026-02-17
HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors
M.D. Anderson Cancer Center
Phase 1 Recruiting
NCT05565118 2026-02-17
Prospective Surgical Study on the Pattern of Electrical Activity in High Grade Glioma as a Predictor of Progression
Case Comprehensive Cancer Center
Phase 1 Recruiting
NCT03681028 2026-02-12
Feasibility of Individualized Therapy for Recurrent Glioblastoma
University of California, San Francisco
Phase 1 Completed
NCT06650163 2026-02-05
Zr-89 Crefmirlimab Berdoxam and Immuno-Positron Emission Tomography for the Imaging of Patients With Resectable Brain Tumors
Jonsson Comprehensive Cancer Center
Phase 1 Recruiting
NCT03389230 2026-02-04
Memory-Enriched T Cells in Treating Patients With Recurrent or Refractory Grade III-IV Glioma
City of Hope Medical Center
Phase 1 Active not recruiting
NCT05660369 2026-02-04
CARv3-TEAM-E T Cells in Glioblastoma
Massachusetts General Hospital
Phase 1 Recruiting
NCT03334305 2026-01-29
ACTION
University of Florida
Phase 1 Terminated
NCT05762419 2026-01-28
FUS Etoposide for DMG
Columbia University
Phase 1 Recruiting
NCT04309552 2026-01-27
Tumor Hypoxia and Proliferation in Patients With High-Grade Glioma
Weill Medical College of Cornell University
Phase 1 Suspended
NCT06193174 2026-01-22
Re-Administration of C134 in Patients With Recurrent GBM (C134-HSV-1)
University of Alabama at Birmingham
Phase 1 Terminated
NCT05835687 2026-01-20
Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS Tumors
St. Jude Children's Research Hospital
Phase 1 Recruiting
NCT06355908 2026-01-20
ENHANCING
Beijing Tiantan Hospital
Phase 1 Suspended
NCT06666712 2026-01-13
TPT CED rHGG
Columbia University
Phase 1 Recruiting
NCT07331064 2026-01-09
GABRIEL
Medical College of Wisconsin
Phase 1 Not yet recruiting
NCT06724926 2026-01-02
Concurrent Azeliragon With Craniospinal Irradiation
NYU Langone Health
Phase 1 Recruiting
NCT07306299 2025-12-29
A Phase I Clinical Trial of a mRNA Vaccine for Recurrent or Progressive High-grade Glioma
Second Affiliated Hospital, School of Medicine, Zhejiang University
Phase 1 Recruiting
NCT02473380 2025-12-19
GLIOSPECT
Hospices Civils de Lyon
Phase 1 Completed
NCT07031765 2025-12-18
Peds CHAMP1ON
University of Florida
Phase 1 Active not recruiting
NCT03500991 2025-12-17
HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors
Seattle Children's Hospital
Phase 1 Active not recruiting
NCT03638167 2025-12-17
EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors
Seattle Children's Hospital
Phase 1 Completed
NCT05686798 2025-12-16
Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.
Henry Ford Health System
Phase 1 Recruiting
NCT04185038 2025-12-15
Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors
Seattle Children's Hospital
Phase 1 Recruiting
NCT05030298 2025-11-21
Preoperative Radiosurgery for the Treatment of High Grade Glioma, NeoGlioma Trial
Mayo Clinic
Phase 1 Recruiting
NCT05293197 2025-11-20
SONOKID
Assistance Publique - Hôpitaux de Paris
Phase 1 Recruiting
NCT02192359 2025-11-14
Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas
City of Hope Medical Center
Phase 1 Active not recruiting
NCT07223034 2025-11-04
A Study of 177Lu-PSMA-617 in People With Gliomas
Memorial Sloan Kettering Cancer Center
Phase 1 Recruiting
NCT06964737 2025-10-29
Anti-GARP Chimeric Antigen Receptor T Cell Therapy for the Treatment of Recurrent Grade III or IV Gliomas
Ohio State University Comprehensive Cancer Center
Phase 1 Recruiting
NCT04826393 2025-10-22
ASP8374 + Cemiplimab in Recurrent Glioma
Dana-Farber Cancer Institute
Phase 1 Completed
NCT05341947 2025-10-22
Activated Autologous T Cells Against Glioma Cancer Stem Cell Antigens for Patients With Recurrent Glioblastoma
Cedars-Sinai Medical Center
Phase 1 Withdrawn
NCT04214392 2025-10-06
Chimeric Antigen Receptor (CAR) T Cells With a Chlorotoxin Tumor-Targeting Domain for the Treatment of MMP2+ Recurrent or Progressive Glioblastoma
City of Hope Medical Center
Phase 1 Active not recruiting
NCT06169280 2025-10-06
Repeated Neural Stem Cell Based Virotherapy for Newly Diagnosed High Grade Glioma
Northwestern University
Phase 1 Recruiting
NCT02062827 2025-10-02
M032-HSV-1
University of Alabama at Birmingham
Phase 1 Active not recruiting
NCT04772456 2025-09-22
Hyperpolarized 13C-pyruvate Metabolic MRI With Infiltrating Gliomas
University of Maryland, Baltimore
Phase 1 Recruiting
NCT04808245 2025-09-22
INTERCEPT-H3
German Cancer Research Center
Phase 1 Active not recruiting