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Has results × Gliosarcoma × binimetinib × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1 CNS 1

Conditions

Melanoma 12 Colorectal Neoplasms 6 Carcinoma, Non-Small-Cell Lung 6 Neoplasm Metastasis 5 Neoplasms 4 Lung Neoplasms 4 Brain Neoplasms 4 Skin Neoplasms 2 Skin Diseases 2 Hematologic Neoplasms 2 Uveal Melanoma 1 Triple Negative Breast Neoplasms 1 Spinocerebellar Degenerations 1 Solid Tumors Harboring a BRAF V600 Mutation 1 Soft Tissue Neoplasms 1 Peripheral Nervous System Neoplasms 1 Parkinson Disease 4, Autosomal Dominant Lewy Body 1 Pancreatic Neoplasms 1 Noonan Syndrome 5 1 Neurofibromatosis 1 1 Neurofibromatoses 1 Neurofibroma, Plexiform 1 Neurofibroma 1 Multiple Myeloma 1 Lymphoma 1 Lymphatic Metastasis 1 Low-grade Serous Ovarian Cancer 1 Leukemia, Myeloid, Acute 1 Hereditary Sensory and Autonomic Neuropathies 1 Gliosarcoma 1

Interventions

Temozolomide 48 Bevacizumab 31 Radiotherapy 24 Radiation 11 Erlotinib Hydrochloride 11 Radiotherapy, Intensity-Modulated 7 Radiotherapy, Conformal 7 Irinotecan 6 Vorinostat 5 Immunoglobulin G 4 Disulfides 4 Carmustine 4 plerixafor 3 carmustine, poliferprosan 20 drug combination 3 Sorafenib 3 Sirolimus 3 Radiosurgery 3 Magnetic Resonance Spectroscopy 3 Everolimus 3 Dasatinib 3 Bortezomib 3 veliparib 2 vandetanib 2 temsirolimus 2 tandutinib 2 sargramostim 2 pazopanib 2 ferric pyrophosphate 2 cediranib 2 Topotecan 2

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT03973918 2024-10-31

BRAF

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase 2 Terminated

5 enrolled 15 charts

Astrocytoma, Glioblastoma, Glioma, Gliosarcoma

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