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Recent Start date Enrollment

Gliosarcoma × binimetinib × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1 CNS 1

Conditions

Melanoma 34 Carcinoma, Non-Small-Cell Lung 15 Lung Neoplasms 10 Colorectal Neoplasms 10 Neoplasm Metastasis 9 Brain Neoplasms 8 Neoplasms 7 Pancreatic Neoplasms 6 Triple Negative Breast Neoplasms 5 Skin Neoplasms 4 Ovarian Neoplasms 3 Gastrointestinal Stromal Tumors 3 Biliary Tract Neoplasms 3 Thyroid Neoplasms 2 Skin Diseases 2 Recurrence 2 Rectal Neoplasms 2 Neurofibromatosis 1 2 Multiple Myeloma 2 Leukemia, Hairy Cell 2 Hereditary Sensory and Autonomic Neuropathies 2 Hematologic Neoplasms 2 Glioma 2 Fallopian Tube Neoplasms 2 Colonic Neoplasms 2 Breast Neoplasms 2 Uveal Melanoma 1 Spinocerebellar Degenerations 1 Solid Tumors Harboring a BRAF V600 Mutation 1 Solid Tumors 1

Interventions

Temozolomide 119 Radiotherapy 80 Bevacizumab 39 Radiation 30 Carmustine 25 Irinotecan 20 Magnetic Resonance Spectroscopy 19 Erlotinib Hydrochloride 19 Chemotherapy, Adjuvant 17 Surgical Procedures, Operative 13 Carboplatin 13 sargramostim 12 O(6)-benzylguanine 12 Radiotherapy, Intensity-Modulated 10 Radiotherapy, Conformal 10 Thalidomide 8 Imatinib Mesylate 8 Drug Therapy 8 Radiosurgery 7 Procarbazine 7 Gene Expression Profiling 7 pembrolizumab 6 motexafin gadolinium 6 cediranib 6 Vorinostat 6 Lomustine 6 Immunohistochemistry 6 Gefitinib 6 Filgrastim 6 Everolimus 6

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT03973918 2024-10-31

BRAF

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase 2 Terminated

5 enrolled 15 charts

Astrocytoma, Glioblastoma, Glioma, Gliosarcoma

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