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Clinical Trials

1 trials

Recent Start date Enrollment

Phase 2 × Gliosarcoma × binimetinib × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1 CNS 1

Conditions

Melanoma 17 Brain Neoplasms 6 Carcinoma, Non-Small-Cell Lung 5 Neoplasms 4 Pancreatic Neoplasms 3 Neoplasm Metastasis 3 Lung Neoplasms 3 Colorectal Neoplasms 3 Ovarian Neoplasms 2 Multiple Myeloma 2 Leukemia, Hairy Cell 2 Hematologic Neoplasms 2 Triple Negative Breast Neoplasms 1 Thyroid Neoplasms 1 Skin Neoplasms 1 Recurrence 1 Peripheral Nervous System Neoplasms 1 Noonan Syndrome 5 1 Neurofibromatosis 1 1 Neurofibromatoses 1 Neurofibroma, Plexiform 1 Neurofibroma 1 Lymphoma 1 Lymphatic Metastasis 1 Leukemia, Myeloid, Acute 1 Hereditary Sensory and Autonomic Neuropathies 1 Gliosarcoma 1 Glioma 1 Glioblastoma 1 Fallopian Tube Neoplasms 1

Interventions

Temozolomide 42 Radiotherapy 33 Bevacizumab 30 Carmustine 12 Irinotecan 10 Erlotinib Hydrochloride 10 sargramostim 7 Thalidomide 7 Chemotherapy, Adjuvant 7 Carboplatin 6 pembrolizumab 5 Radiation 5 Magnetic Resonance Spectroscopy 5 Cyclophosphamide 5 Topotecan 4 Surgical Procedures, Operative 4 Drug Therapy 4 Celecoxib 4 cediranib 3 aldesleukin 3 Tamoxifen 3 Radiotherapy, Intensity-Modulated 3 Radiotherapy, Conformal 3 O(6)-benzylguanine 3 Gefitinib 3 Filgrastim 3 FANG vaccine 3 Bortezomib 3 Aminolevulinic Acid 3 pazopanib 2

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT03973918 2024-10-31

BRAF

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase 2 Terminated

5 enrolled 15 charts

Astrocytoma, Glioblastoma, Glioma, Gliosarcoma

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