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OTHER × Gliosarcoma × binimetinib × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1 CNS 1

Conditions

Melanoma 17 Lung Neoplasms 6 Carcinoma, Non-Small-Cell Lung 6 Brain Neoplasms 6 Colorectal Neoplasms 4 Neoplasm Metastasis 3 Triple Negative Breast Neoplasms 2 Recurrence 2 Pancreatic Neoplasms 2 Neoplasms 2 Gastrointestinal Stromal Tumors 2 Breast Neoplasms 2 Biliary Tract Neoplasms 2 Uveal Melanoma 1 Thyroid Neoplasms 1 Soft Tissue Neoplasms 1 Skin Neoplasms 1 Rectal Neoplasms 1 Peripheral Nervous System Neoplasms 1 Non-small Cell Carcinoma 1 Neurofibromatosis 1 1 Neurofibromatoses 1 Neurofibroma, Plexiform 1 Neurofibroma 1 Multiple Myeloma 1 Leukemia, Myeloid, Chronic-Phase 1 Leukemia 1 Gliosarcoma 1 Glioma 1 Glioblastoma 1

Interventions

Temozolomide 80 Radiotherapy 47 Bevacizumab 29 Irinotecan 18 Radiation 15 Erlotinib Hydrochloride 14 Carmustine 13 Magnetic Resonance Spectroscopy 12 O(6)-benzylguanine 10 Chemotherapy, Adjuvant 10 sargramostim 8 Thalidomide 8 Imatinib Mesylate 8 Carboplatin 8 Gene Expression Profiling 6 Filgrastim 6 Drug Therapy 6 Surgical Procedures, Operative 5 Radiotherapy, Intensity-Modulated 5 Hydroxyurea 5 Gefitinib 5 pembrolizumab 4 aldesleukin 4 Topotecan 4 Immunohistochemistry 4 Etoposide 4 Dasatinib 4 Celecoxib 4 Biopsy 4 Aminolevulinic Acid 4

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT03973918 2024-10-31

BRAF

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase 2 Terminated

5 enrolled 15 charts

Astrocytoma, Glioblastoma, Glioma, Gliosarcoma

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