Dose Escalation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma
Phase 1 Completed
17 enrolled
Tinostamustine With or Without Radiation Therapy in Treating Patients With Newly Diagnosed MGMT-Unmethylated Glioblastoma
Phase 1 Completed
5 enrolled
Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade Gliomas
Phase 1 Completed
17 enrolled 11 charts
Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma
Phase 1 Completed
29 enrolled
Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children
Phase 1 Completed
8 enrolled 9 charts
Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas
Phase 1 Completed
46 enrolled 20 charts
HSV G207 Alone or With a Single Radiation Dose in Children With Progressive or Recurrent Supratentorial Brain Tumors
Phase 1 Completed
13 enrolled
Anti-LAG-3 Alone & in Combination w/ Nivolumab Treating Patients w/ Recurrent GBM (Anti-CD137 Arm Closed 10/16/18)
Phase 1 Completed
63 enrolled
INC280 Combined With Bevacizumab in Patients With Glioblastoma Multiforme
Phase 1 Completed
65 enrolled
Temozolomide + Everolimus in Newly Diagnosed, Recurrent, or Progressive Malignant Glioblastoma Multiforme
Phase 1 Completed
32 enrolled
EGFR Inhibition Using Weekly Erlotinib for Recurrent Malignant Gliomas
Phase 1 Completed
22 enrolled
Evaluate the Safety and Effectiveness of Intranasal Administration of Temozolomide in Patients With Glioblastoma
Phase 1 Completed
30 enrolled
ATTAC
Phase 1 Completed
42 enrolled
BG & TMZ Therapy of Glioblastoma Multiforme
Phase 1 Completed
10 enrolled
Ipilimumab and/or Nivolumab in Combination With Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma or Gliosarcoma
Phase 1 Completed
32 enrolled
Genetically Modified Neural Stem Cells, Flucytosine, and Leucovorin for Treating Patients With Recurrent High-Grade Gliomas
Phase 1 Completed
16 enrolled 16 charts
BPM31510 in Treating Patients With Recurrent High-Grade Glioma Previously Treated With Bevacizumab
Phase 1 Completed
12 enrolled
REGULATe
Phase 1 Completed
34 enrolled
Dose Escalation Study to Determine the Safety of IFN-Beta Gene Transfer in the Treatment of Grade III & Grade IV Gliomas
Phase 1 Completed
12 enrolled
Vaccine Therapy in Treating Patients With Malignant Glioma
Phase 1 Completed
28 enrolled
Erlotinib and Sirolimus in Treating Patients With Recurrent Malignant Glioma
Phase 1 Completed
19 enrolled
Sodium Stibogluconate and IFNa-2b Followed By CDDP, VLB and DTIC Treating Pts.With Advanced Melanoma or Other Cancers
Phase 1 Completed
22 enrolled
Study of the IDO Pathway Inhibitor, Indoximod, and Temozolomide for Pediatric Patients With Progressive Primary Malignant Brain Tumors
Phase 1 Completed
81 enrolled
Dimethyl Fumarate, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Phase 1 Completed
12 enrolled
Gene Therapy in Treating Patients With Primary Brain Tumors
Phase 1 Completed
Tumor Tissue Analysis in Patients Receiving Imatinib Mesylate for Malignant Glioma
Phase 1 Completed
3 enrolled
O(6)-Benzylguanine in Treating Patients With Malignant Glioma
Phase 1 Completed
Gene Therapy in Treating Patients With Recurrent Malignant Gliomas
Phase 1 Completed
Gadolinium Texaphyrin Plus Radiation Therapy in Treating Patients With Supratentorial Glioblastoma Multiforme
Phase 1 Completed
6 enrolled
Gefitinib Plus Temozolomide in Treating Patients With Malignant Primary Glioma
Phase 1 Completed
ABT-888, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Phase 1 Completed
24 enrolled
Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic Astrocytoma
Phase 1 Completed
9 enrolled 10 charts
A Feasibility, Dose-Escalation Study Using Intracerebral Microdialysis to Assess the Neuropharmacodynamics of Temsirolimus in Patients With Primary or Metastatic Brain Tumors
Phase 1 Completed
12 enrolled
Bafetinib in Treating Patients With Recurrent High-Grade Glioma or Brain Metastases
Phase 1 Completed
7 enrolled
Olaparib and Temozolomide in Treating Patients With Relapsed Glioblastoma
Phase 1 Completed
34 enrolled
A Pilot Feasibility Study of Oral 5-Fluorocytosine and Genetically-Modified Neural Stem Cells Expressing E.Coli Cytosine Deaminase for Treatment of Recurrent High Grade Gliomas
Phase 1 Completed
15 enrolled
Cellular Adoptive Immunotherapy Using Genetically Modified T-Lymphocytes in Treating Patients With Recurrent or Refractory High-Grade Malignant Glioma
Phase 1 Completed
3 enrolled
p28 in Treating Younger Patients With Recurrent or Progressive Central Nervous System Tumors
Phase 1 Completed
18 enrolled
Vaccine Therapy and Sargramostim in Treating Patients With Malignant Glioma
Phase 1 Completed
9 enrolled
Vaccine Therapy in Treating Patients Undergoing Surgery for Recurrent Glioblastoma Multiforme
Phase 1 Completed
50 enrolled
Iodine I 131 Monoclonal Antibody TNT-1/B in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme
Phase 1 Completed
22 enrolled
ZAP IT
Phase 1 Completed
16 enrolled
Imatinib Mesylate, Vatalanib, and Hydroxyurea in Treating Patients With Recurrent or Relapsed Malignant Glioma
Phase 1 Completed
37 enrolled
Vaccine Therapy, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Phase 1 Completed
45 enrolled
Vaccine Therapy in Treating Patients With Malignant Glioma
Phase 1 Completed
8 enrolled
RO4929097, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma
Phase 1 Completed
22 enrolled
CC-5013 in Treating Patients With Recurrent Glioma
Phase 1 Completed
CC-8490 in Treating Patients With Recurrent or Refractory High-Grade Gliomas
Phase 1 Completed
Radiation Therapy in Treating Patients With Glioblastoma
Phase 1 Completed
34 enrolled
Chemotherapy Followed by Radiation Therapy in Treating Patients With Malignant Glioma
Phase 1 Completed