Eligibility Screening for the NIH Intramural Research Program Clinical Protocols
Completed
19,522 enrolled
Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer
Phase 1 Completed
58 enrolled 17 charts
Vorinostat and Combination Chemotherapy With Rituximab in Treating Patients With HIV-Related Diffuse Large B-Cell Non-Hodgkin Lymphoma or Other Aggressive B-Cell Lymphomas
Phase 1/2 Completed
107 enrolled 24 charts
Phase II Study of Dose-Adjusted EPOCH-Rituximab in Adults With Untreated Burkitt Lymphoma and c-MYC+ Diffuse Large B-Cell Lymphoma
Phase 2 Completed
194 enrolled 19 charts
Cabozantinib S-Malate in Treating Patients With Advanced Solid Tumors and Human Immunodeficiency Virus
Phase 1 Completed
36 enrolled 18 charts
Lenalidomide in Treating Patients With AIDS-Associated Kaposi's Sarcoma
Phase 1/2 Completed
38 enrolled 11 charts
A Multicenter, Double Blind, Comparative Study of Zidovudine Alone Versus Zidovudine and Acyclovir as Treatment for HIV-Infected Patients With CD4+ Counts Less Than 200 Cells/mm3
Phase 2 Completed
400 enrolled
A Phase III Randomized Trial of Topical Vaginal Fluorouracil (5-Fluorouracil, 5-FU) Maintenance Therapy Versus Observation After Standard Treatment for High-Grade Cervical Dysplasia in HIV-Infected Women
Phase 3 Completed
158 enrolled
A Study of Chemotherapy Plus Azidothymidine in the Treatment of Kaposi's Sarcoma in Patients With AIDS
Phase 1 Completed
36 enrolled
A Study of Doxorubicin in the Treatment of AIDS-Related Kaposi's Sarcoma
Phase 2 Completed
48 enrolled
A Study of Tumor Necrosis Factor and Human Interferon-gamma in Patients With AIDS Related Complex
Phase 2 Completed
30 enrolled
Safety and Effectiveness of Giving Isotretinoin to HIV-Infected Women to Treat Cervical Tumors
Phase 3 Completed
150 enrolled
A Study of AZT Plus Human Interferon Alpha in the Treatment of AIDS-Related Kaposi's Sarcoma
Phase 1 Completed
48 enrolled
A Phase III Randomized Trial of Low-Dose Versus Standard-Dose mBACOD Chemotherapy With rGM-CSF for Treatment of AIDS-Associated Non-Hodgkin's Lymphoma
Phase 3 Completed
250 enrolled
Phase I Study of Weekly Oral VP-16 for AIDS-Associated Kaposi's Sarcoma
Phase 1 Completed
24 enrolled
A Phase I Study of the Combination of Recombinant GM-CSF, AZT, and Chemotherapy (ABV) (Adriamycin, Bleomycin, Vincristine) in AIDS and Kaposi's Sarcoma
Phase 1 Completed
24 enrolled
Phase II Study of Zidovudine and Recombinant Alpha-2A Interferon in the Treatment of Patients With AIDS-Associated Kaposi's Sarcoma
Phase 2 Completed
60 enrolled
Chemotherapy and Azidothymidine, With or Without Radiotherapy, for High Grade Lymphoma in AIDS-Risk Group Members
Phase NA Completed
45 enrolled
A Phase I Study of AZT and Human Interferon Alpha (Recombinant Alpha-2A and Lymphoblastoid) in the Treatment of AIDS-Associated Kaposi's Sarcoma
Phase 1 Completed
56 enrolled
Pentoxifylline (Trental) as a Modulator of Tumor Necrosis Factor and of HIV Replication in Patients With AIDS
Phase 1 Completed
54 enrolled
Phase I Trial of mBACOD and Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) in AIDS-Associated Large Cell, Immunoblastic, and Small Non-cleaved Lymphoma
Phase 1 Completed
18 enrolled
A Phase I Trial of Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor (rHuGM-CSF), Recombinant Alpha Interferon and Azidothymidine (AZT) in AIDS-Associated Kaposi's Sarcoma
Phase 1 Completed
18 enrolled
The Safety and Effectiveness of Interferon Alfa-2B Plus Didanosine in Patients With Kaposi's Sarcoma
Phase 2 Completed
90 enrolled
A Study to Evaluate the Ability of TNFR:Fc to Decrease the Amount of IL-6 (Interleukin-6) and TNF-alpha (Tumor Necrosis Factor) in HIV-Infected Patients
Phase NA Completed
18 enrolled
Pneumococcal Vaccine and Routine Pediatric Immunizations in HIV-Infected Children Receiving Anti-HIV Drugs
Phase NA Completed
300 enrolled
A Study of Chemotherapy Plus ddI or ddC in the Treatment of AIDS-Related Kaposi's Sarcoma
Phase 1 Completed
72 enrolled
Chemoprevention of Anal Neoplasia Arising Secondary to Anogenital Human Papillomavirus Infection in Persons With HIV Infection.
Phase 1 Completed
98 enrolled
A Phase I/II Study of Recombinant Interleukin-4 in AIDS and Kaposi's Sarcoma
Phase 1 Completed
48 enrolled
Phase II Evaluation of Low-Dose Oral Etoposide for the Treatment of Relapsed or Progressed AIDS-Related Kaposi's Sarcoma After Systemic Chemotherapy
Phase 2 Completed
41 enrolled
Phase II Study of Filgrastim (G-CSF) Plus ABVD in the Treatment of HIV-Associated Hodgkin's Disease
Phase 2 Completed
27 enrolled
Development of Serologic Assays for Human Herpes Virus-8
Completed
394 enrolled
Genetic Susceptibility to Oncogenic Viruses
Completed
2,580 enrolled
The Use of a Distress Thermometer in a Pediatric Research Setting: An Exploratory Pilot Study
Completed
289 enrolled
Effects of Potent Antiretroviral Therapy on Kaposi s Sarcoma
Completed
24 enrolled
Bortezomib in Treating Patients With Relapsed or Refractory AIDS-Related Kaposi Sarcoma
Phase 1 Completed
24 enrolled
Bevacizumab to Treat Kaposi's Sarcoma in HIV-Positive and HIV-Negative Patients
Phase 2 Completed
19 enrolled 10 charts
Clinical, Laboratory and Epidemiologic Pilot Studies of Individuals at High Risk for Viral-Associated Cancers
Completed
24 enrolled
Evaluation of Brain Lesions in HIV-infected Patients for Diagnosis of Primary Central Nervous System Lymphoma
Completed
120 enrolled
HIV Infection and Tobacco Use Among Injection Drug Users in Baltimore, Maryland: A Pilot Study of Biomarkers
Completed
The Effect of Anti-HIV Treatment on Body Characteristics of HIV-Infected Children
Completed
100 enrolled
A Study of Anal Cancer Development in HIV Infected People
Completed
560 enrolled
The Effects of Combination Anti-HIV Medication on Human Papillomavirus (HPV) in HIV-Infected Women
Completed
160 enrolled
Phase II Trial of Sequential Chemotherapy and Radiotherapy for AIDS-Related Primary Central Nervous System Lymphoma
Phase 2 Completed
33 enrolled
Comparison of Liposomal Doxorubicin Used Alone or in Combination With Bleomycin Plus Vincristine in the Treatment of Kaposi's Sarcoma in Patients With AIDS
Phase 2 Completed
120 enrolled
A Study of Patients With AIDS Syndrome
Completed
5,000 enrolled
Genetic Factors and Interrelationships for Sexual Orientation, Susceptibility to HIV and Kaposi's Sarcoma, Alcoholism and Psychological Traits, and Histocompatibility Antigens
Completed
2,000 enrolled
Evaluation and Natural History of Children With Cancer and AIDS
Completed
110 enrolled
Home Treatment of HIV-Infected Patients With Interleukin-2 With or Without a Tumor Necrosis Factor Antagonist
Phase 2 Completed
85 enrolled
Genetic Factors and Interrelationships for Cancer Risk-Related Behaviors and Complex Traits
Completed
4,500 enrolled
Thalidomide to Treat Oral Lesions in HIV-Infected Patients
Phase 2 Completed
110 enrolled