Clinical Trials

25 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT03082534 2026-01-28

Pembrolizumab Combined With Cetuximab for Treatment of Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma

78 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Neoplasm Metastasis, Oropharyngeal Neoplasms, Recurrence

NCT06998069 2025-12-30

Head and Neck Cancer Study Project in the Geriatric Population

Phase 3 Recruiting

20 enrolled

Phase 2 Active not recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT01154920 2025-12-17

Paclitaxel, Carboplatin and Cetuximab (PCC) With Cetuximab, Docetaxel, Cisplatin and Fluorouracil (C-TPF) in Previously Untreated Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma

128 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT06912087 2025-12-02

Dose Finding Study of Zanzalintinib With Pembrolizumab and Cetuximab in Head and Neck SCC

Phase 1 Recruiting

36 enrolled

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Neoplasm Metastasis, Neoplasm Recurrence, Local

NCT00875849 2025-09-30

AACER

53 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Tongue Neoplasms

NCT01326468 2025-09-25

Torisel in Addition to Standard Chemotherapy With Radiation for Advanced Head and Neck Cancer

Phase NA Withdrawn

Head and Neck Neoplasms

NCT04722523 2025-09-23

A Study of Cemiplimab With Chemotherapy and Immunotherapy in People With Head and Neck Cancer

Phase 1 Recruiting

40 enrolled

Phase EARLY_PHASE1 Active not recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT05816785 2025-09-03

Pilot Study of Imatinib Cetuximab Combo for H & N Cancer

15 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00665392 2025-08-01

ECHO-07

42 enrolled 24 charts

Phase 3 Active not recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Tongue Neoplasms

NCT02999087 2025-05-07

REACH

707 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT06477692 2025-04-08

Invert-Prospective Phase II Randomized Trial of Involved Nodal Versus Elective Neck RadioTherapy

80 enrolled

Phase 2 Active not recruiting

Head and Neck Neoplasms

NCT03646461 2025-04-06

Trial of Ibrutinib Combined With Nivolumab or Cetuximab to Treat Recurrent/Metastatic HNSCC

5 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT06869473 2025-03-14

AVEC-119

67 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT02573493 2024-12-27

APA

96 enrolled 34 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00868491 2024-10-18

Induction Chemotherapy Followed by Chemoradiation With Cetuximab in Head and Neck Cancer

30 enrolled

Head and Neck Neoplasms

NCT03422536 2024-09-04

Ficlatuzumab w/wo Cetuximab in Patients w/Cetuximab-Resistant, Recurrent or Metastatic Head/Neck Squamous Cell Carcinoma

78 enrolled 16 charts

Phase 2 Active not recruiting

Lymphoid Interstitial Pneumonia, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Lip Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT03494322 2024-05-08

EACH

130 enrolled

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT01979211 2024-02-29

Post-operative Radiation With Cetuximab for Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and Neck

24 enrolled 11 charts

Head and Neck Neoplasms

NCT01588431 2024-02-14

Bevacizumab/Ph 2 for Locally Advanced Head and Neck Cancer

3 enrolled 7 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT01437449 2024-01-30

Docetaxel, Cisplatin, and Cetuximab (TPC) in Palliative Treatment of Patients With Squamous Cell Carcinoma of the Head and Neck (SCCHN)

27 enrolled 13 charts

Head and Neck Neoplasms

NCT03691714 2023-12-08

Durvalumab (MEDI4736) With Cetuximab in Previously Treated Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Phase 2 Unknown

36 enrolled

Head and Neck Neoplasms, Neoplasm Metastasis

NCT02624128 2023-11-13

V-CHANCE

Phase 2 Unknown

39 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplasm Metastasis, Recurrence

NCT05260671 2023-10-18

Penpulimab in Combination With Cetuximab as First-line Treatment in R/M SCCHN

48 enrolled

Head and Neck Neoplasms, Neoplasm Metastasis, Recurrence

NCT03769311 2023-05-24

Cetuximab in Head and Neck Cancer Patients

15 enrolled 8 charts

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT04359199 2023-02-10

QUASAR

Unknown

42 enrolled

Squamous Cell Carcinoma of Head and Neck, Deglutition Disorders, Head and Neck Neoplasms, Oropharyngeal Neoplasms

NCT01553032 2022-05-25

HICARE

Phase 4 Completed

139 enrolled

Head and Neck Neoplasms

NCT03067610 2022-03-17

INFIELD

72 enrolled 14 charts

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Mouth Neoplasms, Pharyngeal Neoplasms

NCT00660218 2021-11-08

A Phase I/II Study of Radiation Therapy, Paclitaxel Poliglumex and Cetuximab in Advanced Head and Neck Cancer

Phase 1/2 Completed

53 enrolled

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT03887442 2021-01-07

EXTAX

Phase 2 Terminated

17 enrolled 8 charts

Head and Neck Neoplasms, Neoplasm Metastasis, Recurrence

NCT01412229 2020-11-23

Induction Chemotherapy for Locally Advanced Squamous Cell Carcinoma of the Head and Neck

40 enrolled 14 charts

Head and Neck Neoplasms

NCT01020864 2020-11-02

CECAVI

Phase 2 Withdrawn

Head and Neck Neoplasms

NCT01969877 2020-09-02

ARTSCANIII

Phase 3 Completed

298 enrolled

Head and Neck Neoplasms

NCT00833261 2020-08-21

Nab-Paclitaxel, Cetuximab, Cisplatin, and Radiation Therapy in Treating Patients With Recurrent Head and Neck Cancer

37 enrolled 6 charts

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Tongue Neoplasms, Carcinoma, Verrucous

NCT00851877 2020-08-21

Nab-Paclitaxel, Cisplatin, and Cetuximab With Concurrent Radiation Therapy for Locally Advanced Head and Neck Cancer

Phase 1/2 Completed

37 enrolled 9 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Tongue Neoplasms

NCT02124707 2020-08-12

Weekly Carboplatin, Paclitaxel and Cetuximab Treatment for Patients With Recurrent or Metastatic SCCHN

14 enrolled 17 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Neoplasm Metastasis, Recurrence

NCT02015650 2020-05-18

Cetuximab Compared to Mitomycin-C and 5-Fluorouracil for Locally Advanced Squamous Cell Carcinomas of the Head and Neck

Phase 4 Terminated

4 enrolled

Head and Neck Neoplasms

NCT01133678 2020-05-08

Study in Locally Advanced Squamous Cell Carcinoma of Head and Neck

Phase 2 Terminated

50 enrolled 9 charts

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT00721513 2020-04-07

Docetaxel, Cisplatin, and Fluorouracil Followed By Cetuximab and Radiation Therapy in Treating Patients With Locally Advanced Head and Neck Cancer

20 enrolled 17 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00957853 2020-03-19

Preoperative Treatment With Cetuximab and/or IMC-A12

16 enrolled 8 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplasms

NCT00524017 2020-03-12

Cetuximab in Treating Patients With Precancerous Lesions of the Upper Aerodigestive Tract

Head & NeckOther neoplasm

35 enrolled 6 charts

Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Precancerous Conditions, Salivary Gland Neoplasms

NCT00468169 2019-10-09

EPIC

110 enrolled 14 charts

Carcinoma, Head and Neck Neoplasms, Neoplasms

NCT01758731 2019-09-23

Study of Olaparib With Radiation Therapy and Cetuximab in Advanced Head and Neck Cancer With Heavy Smoking History

Phase 1 Completed

17 enrolled 8 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Smoking

NCT01581970 2019-09-11

Potentiation of Cetuximab by Tregs Depletion With CSA in Advanced Head & Neck Cancer

7 enrolled 9 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplasms, Squamous Cell

NCT00343083 2019-08-19

Evaluation of Cetuximab (ERBITUX) and Concurrent Carboplatin, Paclitaxel & Radiotherapy in the Management of Patients With Advanced Locoregional Squamous Cell Carcinomas of the Head and Neck (GCC 0442)

43 enrolled 11 charts

Head and Neck Neoplasms

NCT00716391 2019-05-24

TPF Plus Cisplatin and Radiotherapy vs TPF Plus Cetuximab and Radiotherapy to Treat Head and Neck Cancer.

Phase 3 Completed

519 enrolled

Head and Neck Neoplasms

NCT00765011 2019-04-11

TPF Plus Radiotherapy and Cetuximab to Avoid Total Laryngectomy in Patients With Larynx Cancer

94 enrolled

Head and Neck Neoplasms

NCT00934518 2019-02-12

Image Guided Intensity Modulated Reirradiation (IG-IMRT) With Cetuximab for Locoregionally Confined Recurrent Head and Neck Squamous Cell Carcinoma

Phase 2 Withdrawn