Clinical Trials Browser

Interventional × Head and Neck Neoplasms × Radiation × Clear all

NCT07209189 2026-03-09

(NeoScorch HN)

Phase 2 Recruiting

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms, Papillomavirus Infections

NCT03210103 2026-01-28

ORATOR2

Phase NA Active not recruiting

Head and Neck Neoplasms, Oropharyngeal Neoplasms

NCT02586207 2025-10-07

Pembrolizumab in Combination With CRT for LA-SCCHN

Phase 1 Completed

59 enrolled 9 charts

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Diseases, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT03247712 2025-07-10

Neoadjuvant Immunoradiotherapy in Head & Neck Cancer

Phase 1/2 Active not recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00405405 2025-05-06

Phase I of Biologics and Chemoradiation Therapy for Advanced Head and Neck Cancer

Phase 1 Completed

DermatologicHead & Neck

Head and Neck Neoplasms, Melanoma, Parotid Neoplasms, Thyroid Neoplasms

NCT03085719 2025-02-25

Targeting PD-1 Therapy Resistance With Focused High or High and Low Dose Radiation in SCCHN

Phase 2 Active not recruiting

18 enrolled 22 charts

Head and Neck Neoplasms

NCT03132922 2024-01-22

MAGE-A4ᶜ¹º³²T for Multi-Tumor

Phase 1 Active not recruiting

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

Adenocarcinoma, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Head and Neck Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Sarcoma, Stomach Neoplasms, Sarcoma, Synovial, Liposarcoma, Myxoid

NCT04892875 2023-11-30

PANTHEoN

Phase 1 Withdrawn

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms, Pharyngeal Neoplasms

NCT00702481 2023-02-28

Study of Nimotuzumab and Cisplatin/Radiotherapy for Locally Advanced Head and Neck Squamous Cell Cancer

Phase 2 Completed

Head and Neck Neoplasms

NCT03982537 2022-12-19

Effect of N-Acetyl Cysteine (NAC) on the Oral Microbiome

Phase 2 Withdrawn

Head and Neck Neoplasms

NCT05023863 2021-08-27

The Effect of Alpha Lipoic Acid on the Incidence and Severity of Radiotherapy-Induced Oral Mucositis in Head and Neck Cancer Patients

Phase 2/3 Unknown

Head & NeckOther

Head and Neck Neoplasms, Mucositis

NCT04220749 2020-09-04

Radiotherapy vs. Trans-Oral Surgery for HPV-Negative Oropharyngeal Squamous Cell Carcinoma

Phase 2 Recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT02567383 2020-07-28

Combination of Hyperthermia and Concurrent Chemoradiotherapy (CCRT) for Recurrent Head and Neck Cancer

Phase 2 Unknown

Hyperthermia, Head and Neck Neoplasms

NCT02075112 2019-12-06

Soy Isoflavone in Combination With Radiation Therapy and Cisplatin in SCC of the Head and Neck

Phase 1 Completed

Head and Neck Neoplasms

NCT00343083 2019-08-19

Evaluation of Cetuximab (ERBITUX) and Concurrent Carboplatin, Paclitaxel & Radiotherapy in the Management of Patients With Advanced Locoregional Squamous Cell Carcinomas of the Head and Neck (GCC 0442)

Phase 2 Completed

43 enrolled 11 charts

Head and Neck Neoplasms

NCT02572661 2019-06-27

SUSPECT

Phase NA Completed

Head and Neck Neoplasms

NCT01011842 2019-04-09

Real-Time kV Imaging vs. Real-Time 3D Patient Surface Tracking for Head & Neck Cancer

Phase NA Terminated

Head and Neck Neoplasms

NCT00934518 2019-02-12

Image Guided Intensity Modulated Reirradiation (IG-IMRT) With Cetuximab for Locoregionally Confined Recurrent Head and Neck Squamous Cell Carcinoma

Phase 2 Withdrawn

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT03637335 2018-08-20

METAXIOM

Phase 3 Terminated

Head & NeckThoracic

Head and Neck Neoplasms, Lung Neoplasms, Neoplasm Metastasis

NCT00352118 2017-12-28

Combination Chemotherapy and Radiation Therapy in Treating Patients With Locally Advanced Head and Neck Cancer

Phase 2 Terminated

4 enrolled 4 charts

Head & NeckOther

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Xerostomia, Mucositis

NCT00490061 2017-03-06

Lapatinib and Radiation for Stage III-IV Head and Neck Cancer Patients Who Cannot Tolerate Concurrent Chemotherapy

Phase 2 Terminated

17 enrolled 7 charts

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT00095927 2017-01-04

Randomized Amifostine For SCCHN

Phase 2 Completed

Head & NeckOther

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Radiation Injuries, Xerostomia, Mucositis

NCT00450138 2016-08-29

Open Label, Phase I ZD6474 Head and Neck Cancer Study

Phase 1 Completed

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT00168116 2016-02-24

Xerostomia in Head and Neck Cancer Patients Receiving Radiation as the Primary Treatment Versus Patients Who Will Not Have Such a Procedure

Phase 2 Completed

Head and Neck Neoplasms, Xerostomia

NCT01161498 2016-02-08

Study of Safety and Efficacy of Talimogene Laherparepvec With Cisplatin and Radiotherapy for Treatment of Locally Advanced Head and Neck Cancer

Phase 3 Terminated

5 enrolled 8 charts

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT00176241 2015-06-08

Phase I Trial of Biweekly Gemcitabine & Paclitaxel & Low-Dose Radiation for Metastatic or Recurrent Head & Neck Cancer

Phase 1 Terminated

Head and Neck Neoplasms, Neoplasm Metastasis, Recurrence

NCT02429037 2015-04-29

P53 Gene Combined With Radio- and Chemo-therapy in Treatment of Unresectable Locally Advanced Head and Neck Cancer

Phase 2 Unknown

Head and Neck Neoplasms

NCT01790516 2014-10-02

Use of Pharmacogenetics to Select Erbitux or Cisplatin to Treat Head and Neck Cancer

Phase NA Terminated

2 enrolled 7 charts

Head and Neck Neoplasms