Clinical Trials

Phase 2 Active not recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Oropharyngeal Neoplasms

NCT04609280 2025-07-29

SAVER

52 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Oropharyngeal Neoplasms

NCT05388773 2025-06-19

Transoral Surgical Resection Followed by De-escalated Adjuvant IMRT in Resectable p16+ Locally Advanced Oropharynx Cancer

Phase 2 Recruiting

150 enrolled

Phase 2 Active not recruiting

Carcinoma, Squamous Cell, DNA Virus Infections, Head and Neck Neoplasms, Stomatognathic Diseases, Neoplasms, Glandular and Epithelial, Oropharyngeal Neoplasms, Otorhinolaryngologic Diseases, Otorhinolaryngologic Neoplasms, Papilloma, Pharyngeal Diseases, Pharyngeal Neoplasms, Tumor Virus Infections, Papillomavirus Infections

NCT01220583 2025-02-13

Radiation Therapy With or Without Chemotherapy in Treating Patients With High-Risk Malignant Salivary Gland Tumors That Have Been Removed By Surgery

252 enrolled

Head and Neck Neoplasms, Salivary Gland Neoplasms

NCT02281955 2025-01-07

De-intensification of Radiation and Chemotherapy for Low-Risk HPV-related Oropharyngeal SCC: Follow-up Study

115 enrolled 18 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Oropharyngeal Neoplasms

NCT02573493 2024-12-27

APA

96 enrolled 34 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT05966194 2024-11-15

KEVLARx

Phase 2 Recruiting

216 enrolled

Head & NeckOther

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Mouth Neoplasms, Stomatitis, Mucositis

NCT01530997 2024-11-13

De-intensification of Radiation & Chemotherapy in Low-Risk Human Papillomavirus-related Oropharyngeal Squamous Cell Ca

45 enrolled 22 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Oropharyngeal Neoplasms

NCT02609503 2024-11-05

Pembrolizumab + Radiation for Locally Adv SCC of the Head and Neck (SCCHN) Not Eligible Cisplatin

29 enrolled 27 charts

Phase 2 Not yet recruiting

Head and Neck Neoplasms

NCT06578871 2024-09-03

SUPERIOR

90 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Oropharyngeal Neoplasms

NCT00720304 2024-08-22

Erlotinib, Docetaxel, and Radiation Therapy in Stage III or Stage IV Squamous Cell Carcinoma of the Head and Neck

43 enrolled 16 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT02776163 2024-07-30

Postoperative Concurrent Chemoradiotherapy in Treating Patients With High-Risk Salivary Gland Carcinomas

107 enrolled

Head and Neck Neoplasms

NCT03077243 2024-05-02

P53 Mutational Status and cf HPV DNA for the Management of HPV-associated OPSCC

195 enrolled 19 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Oropharyngeal Neoplasms

NCT04529850 2022-08-16

Ph 2 Open Label Study of GC4419 to Reduce SOM Associated With Chemoradiotherapy for Head and Neck Cancer

38 enrolled 10 charts

Head and Neck Neoplasms, Stomatitis

NCT03067610 2022-03-17

INFIELD

72 enrolled 14 charts

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Mouth Neoplasms, Pharyngeal Neoplasms

NCT00566540 2021-11-26

Ph 2 Intensification Regimen for Previously Untreated, Resectable, Advanced Squamous Cell Cancer

11 enrolled 8 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00833261 2020-08-21

Nab-Paclitaxel, Cetuximab, Cisplatin, and Radiation Therapy in Treating Patients With Recurrent Head and Neck Cancer

37 enrolled 6 charts

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Tongue Neoplasms, Carcinoma, Verrucous

NCT02776137 2020-08-19

Postoperative Concurrent Chemoradiotherapy With Docetaxel for High-Risk Squamous Cell Carcinoma of Head and Neck

91 enrolled

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT00721513 2020-04-07

Docetaxel, Cisplatin, and Fluorouracil Followed By Cetuximab and Radiation Therapy in Treating Patients With Locally Advanced Head and Neck Cancer

20 enrolled 17 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00646659 2018-07-09

Cetuximab, Combination Chemotherapy, and Radiation Therapy in Treating Patients With Newly Diagnosed Stage III or Stage IV Head and Neck Cancer That Cannot Be Removed By Surgery

47 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00423930 2017-08-18

Cisplatin, Bevacizumab, and Intensity-Modulated Radiation Therapy in Treating Patients With Stage III or Stage IV Head and Neck Cancer

44 enrolled 9 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Tongue Neoplasms

NCT01467115 2017-05-09

DREXNECK

1 enrolled

Head and Neck Neoplasms

NCT02047201 2016-03-02

Assessing Tumor Response and IMRT Treat Plan After IC Based on FDG-PET/CT for Locally Advanced HNSCC

40 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT01312493 2015-08-28

Selective IMRT for Locally Advanced Head and Neck Carcinoma With Concurrent Panitumumab

Phase 2 Withdrawn

Head and Neck Neoplasms

NCT00713219 2015-04-23

Docetaxel + Cetuximab + Concurrent Re-Irradiation (Intensity - Modulated Radiation Therapy, IMRT) for Patients With Locoregionally Recurrent Head and Neck Cancer

14 enrolled 6 charts

Head and Neck Neoplasms

NCT01548846 2015-03-13

TOQUAL

11 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00409331 2012-08-07

Amifostine With IMRT for Submandibular and Sublingual Salivary Sparing During Head and Neck Cancer Treatment

3 enrolled 2 charts