Clinical Trials

40 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT03019003 2025-09-16

Oral Decitabine (ASTX727) and Durvalumab in Recurrent and/or Metastatic Head and Neck Cancer Patients

13 enrolled 12 charts

Phase 1 Enrolling by invitation

Head and Neck Neoplasms

NCT05937269 2025-09-09

Assessing Impact of Early Physiotherapy on Lymphatic Dysfunction in Head and Neck Cancer Survivorship

20 enrolled

Head and Neck Neoplasms

NCT04105543 2025-09-02

CLR 131 Combined With Radiation for Head and Neck Cancer

12 enrolled 27 charts

Phase 1 Not yet recruiting

Head and Neck Neoplasms

NCT07072325 2025-08-03

Safety, Tolerability, PK, and Efficacy of CD-001 in Advanced Head & Neck Cancers

9 enrolled

Head and Neck Neoplasms, Neoplasms

NCT05540899 2025-07-24

Testing the Safety of Giving a Standard Dose of Radiation Over a Shorter Period of Time for Patients Who Had Surgery for Intermediate-Risk Head and Neck Cancer

14 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT04477759 2025-07-15

DEHART

18 enrolled 12 charts

Head and Neck Neoplasms, Neoplasms

NCT02474368 2025-07-10

Study Evaluating a Stereotactic Boost/Treatment for Recurrent or Metastatic Cancer of the Head and Neck

21 enrolled

Head and Neck Neoplasms

NCT03336606 2025-07-10

Study of MEDI0562 Prior to Surgical Resection in Head and Neck Squamous Cell Carcinoma (HNSCC) or Melanoma

35 enrolled

DermatologicHead & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Melanoma, Neoplasms, Squamous Cell

NCT04470024 2025-07-10

Phase Ib Trial of Multivalent Autophagosome Vaccine With or Without GITR Agonist, With Anti-PD-1 Immunotherapy in HNSCC

56 enrolled

Head and Neck Neoplasms

NCT03991741 2025-07-03

Adoptive Cell Transfer of Autologous Tumor Infiltrating Lymphocytes and High-Dose Interleukin 2 in Select Solid Tumors

Phase 1 Terminated

3 enrolled 9 charts

DermatologicHead & Neck

Head and Neck Neoplasms, Melanoma, Neoplasm Metastasis

NCT06110195 2025-06-08

Study of Xevinapant With Radiation and Chemotherapy for Patients With Head and Neck Cancer

42 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT06673329 2025-05-14

Brodalumab in the Treatment of Immune-Related Adverse Events

BreastCNSDermatologicGastrointestinalGenitourinaryHead & NeckThoracic

11 enrolled

Brain Neoplasms, Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Mouth Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Skin Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Thyroid Neoplasms

NCT00405405 2025-05-06

Phase I of Biologics and Chemoradiation Therapy for Advanced Head and Neck Cancer

13 enrolled

DermatologicHead & Neck

Head and Neck Neoplasms, Melanoma, Parotid Neoplasms, Thyroid Neoplasms

NCT00328458 2025-05-02

EPO906 Plus Radiation Therapy for the Treatment of Cancer Patients

39 enrolled

CNSHead & Neck

Head and Neck Neoplasms, Central Nervous System Neoplasms

NCT00329589 2025-05-02

A Trial Using Velcade Plus Chemoradiation for Central Nervous System, Head and Neck, and Cervical Cancer Patients

CNSGynecologicHead & Neck

54 enrolled

Brain Neoplasms, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Central Nervous System Neoplasms

NCT00437372 2025-05-02

Phase IB Study Using Sunitinib Plus Radiation Therapy for Cancer Patients

GynecologicHead & NeckThoracic

39 enrolled

Head and Neck Neoplasms, Neoplasms, Nervous System Neoplasms, Pelvic Neoplasms, Thoracic Neoplasms

NCT06446713 2025-04-03

PIRATES

17 enrolled

Head and Neck Neoplasms, Oropharyngeal Neoplasms

NCT02812524 2025-03-10

Ipilimumab for Head and Neck Cancer Patients

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT03245489 2025-01-31

Anti-platelet + Pembro for H&N Tumors

20 enrolled

Head and Neck Neoplasms

NCT04593589 2024-10-22

RESTART

Head and Neck Neoplasms

NCT01818323 2024-10-09

Phase I Trial: T4 Immunotherapy of Head and Neck Cancer

30 enrolled

Head and Neck Neoplasms

NCT06544720 2024-08-09

SCG142 TCR-T Cells for Human Papillomavirus-Associated Carcinomas

GastrointestinalGenitourinaryGynecologicHead & Neck

Anus Neoplasms, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Penile Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms

NCT05183243 2024-07-16

GH21 Capsules for Advanced Solid Tumors: A Study on Safety and Early Results

Phase 1 Unknown

68 enrolled

GastrointestinalHead & NeckThoracic

Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT02308072 2024-05-08

ORCA-2

70 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT05408871 2024-02-15

Non-invasive Measurement of PD-L1 Levels With Positron Emission Tomography (PET) in Head and Neck Malignancies and Intracranial Metastases

Phase 1 Terminated

7 enrolled

Head & NeckThoracic

Head and Neck Neoplasms, Lung Neoplasms, Neoplasm Metastasis

NCT02274155 2024-02-07

Anti-OX40 Antibody in Head and Neck Cancer Patients

17 enrolled

Head and Neck Neoplasms

NCT04892875 2023-11-30

PANTHEoN

Phase 1 Withdrawn

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms, Pharyngeal Neoplasms

NCT02229656 2023-11-07

Olaparib and Radiotherapy in Head and Neck Cancer

Phase 1 Unknown

12 enrolled

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Laryngeal Neoplasms

NCT04337853 2023-11-03

Radiotherapy of Tongue Cancer Using an Intraoral Stent

13 enrolled

Head and Neck Neoplasms, Tongue Neoplasms

NCT01332682 2023-10-18

Resistance Training and Physical Functioning in Head and Neck Cancer Patients

GenitourinaryHead & NeckThoracic

Head and Neck Neoplasms, Laryngeal Neoplasms, Pharyngeal Neoplasms

NCT05259319 2023-10-17

IMMUNOs-SBRT

Phase 1 Unknown

92 enrolled

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Head and Neck Neoplasms, Neoplasms

NCT02897375 2023-10-10

Palbociclib With Cisplatin or Carboplatin in Advanced Solid Tumors

BreastGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

71 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Sarcoma, Colorectal Neoplasms

NCT04456140 2023-07-24

Pro-Active Genetic Testing in Patients With Solid Tumors, Inherit Study