Clinical Trials

BreastGastrointestinalHead & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Mouth Neoplasms

NCT04541381 2026-03-04

The PhOCus Trial: Implementation of Pharmacogenomic Testing in Oncology Care

Phase NA Recruiting

860 enrolled

Breast Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Dihydropyrimidine Dehydrogenase Deficiency

NCT05108870 2026-03-04

TheraT® Vectors (Vaccines) Combined With Chemotherapy to Treat HPV16 Head and Neck Cancers

Phase 1/2 Recruiting

98 enrolled

Head and Neck Neoplasms

NCT05570851 2026-03-04

Alcohol Cessation Among Head and Neck Cancer Survivors

138 enrolled

Alcohol Drinking, Depression, Head and Neck Neoplasms, Social Isolation, Substance-Related Disorders

NCT07065630 2026-03-04

Response-Adaptive Treatment in Untreated Locoregional HPV-Negative Head and Neck Cancer

38 enrolled

Head and Neck Neoplasms

NCT04610645 2026-03-03

ROOCT

Completed

Head and Neck Neoplasms

NCT06208826 2026-03-03

A Single-center Phase II Study to Investigate the Immune Maintenance Therapy Pattern in Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma Who Have Achieved MPR After Neoadjuvant Immunotherapy Combined With Chemotherapy

268 enrolled

Head and Neck Neoplasms

NCT07217938 2026-03-03

TRADstat

48 enrolled

Deglutition Disorders, Head and Neck Neoplasms

NCT07447050 2026-03-03

Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial

BreastGastrointestinalGynecologicHead & NeckSarcomaThoracic

24 enrolled

Breast Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Sarcoma, Stomach Neoplasms, Urogenital Neoplasms, Colorectal Neoplasms

NCT07447570 2026-03-03

Iparomlimab and Tuvonralimab Plus Hypofractionated Radiotherapy and Chemotherapy for HAHNSCC

27 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT05388136 2026-03-02

DeintensiF

Phase NA Terminated

Head and Neck Neoplasms

NCT02589938 2026-02-27

ACUPUNCTURE

Phase NA Completed

258 enrolled 16 charts

Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Radiation Injuries, Salivary Gland Neoplasms, Xerostomia

NCT06239220 2026-02-27

PD-L1 t-haNK, NAI IL-15sa and Cetuximab for Recurrent, Metastatic HNSCC

25 enrolled

Phase EARLY_PHASE1 Active not recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT07435415 2026-02-27

Local Injection Methylene Blue Combined With Radiation in HNSCC Patients

10 enrolled

BreastGastrointestinalHead & NeckThoracic

Head and Neck Neoplasms

NCT07437326 2026-02-27

QVA-Mod

Not yet recruiting

180 enrolled

Breast Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Neoplasms

NCT05898789 2026-02-25

Virtual Rehabilitation for Cancer Survivors

Phase NA Recruiting

388 enrolled

BreastGastrointestinalHead & NeckLymphoid

Breast Carcinoma In Situ, Breast Neoplasms, Head and Neck Neoplasms, Lymphoma, Lymphoproliferative Disorders, Colorectal Neoplasms

NCT07431099 2026-02-25

RECOLOR-HN

Phase NA Not yet recruiting

20 enrolled

Head and Neck Neoplasms

NCT05837221 2026-02-24

Microbiome in Head and Neck Squamous Cell Carcinoma

60 enrolled

Head and Neck Neoplasms, Lip Neoplasms, Mouth Neoplasms, Pharyngeal Neoplasms

NCT06678724 2026-02-24

Establishment of a Microfluidic Based Liquid Biopsy Platform for Recurrent/Metastatic Head and Neck Cancers Prognostication Using NK Cell IFN-γ Expression and CTM Correlation With DS-SACA Chip

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplastic Cells, Circulating

NCT07101432 2026-02-24

Phase I Study of Preconditioning Radiation Therapy With IL-15 Transduced TGFBR2 KO CAR.TROP2-engineered Cord Blood-derived NK Cells in Patients With Advanced Head and Neck Cancer (RADIANCE-NK)

Phase 1 Recruiting

33 enrolled

Head and Neck Neoplasms

NCT07419113 2026-02-24

UNOS

Phase NA Completed

45 enrolled

Phase NA Not yet recruiting

Head and Neck Neoplasms

NCT07431346 2026-02-24

DYSGRAD

80 enrolled

Dysgeusia, Head and Neck Neoplasms

NCT04713449 2026-02-23

Enhancing Self Care Among Oral Cancer Survivors: The Empowered Survival Trial

643 enrolled

Head and Neck Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT07426874 2026-02-23

eHealth Support Tool to Improve Quality of Life in Head and Neck Cancer Survivors

Head and Neck Neoplasms

NCT03483337 2026-02-20

New MRI Biomarkers in Head and Neck Cancers

200 enrolled

Head and Neck Neoplasms, Neoplasm Metastasis, Recurrence, Thyroid Neoplasms

NCT04258813 2026-02-20

ONE TEAM

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

313 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Cardiovascular Diseases, Colonic Neoplasms, Diabetes Mellitus, Esophageal Neoplasms, Head and Neck Neoplasms, Hypercholesterolemia, Hypertension, Liver Neoplasms, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Endometrial Neoplasms

NCT04354064 2026-02-20

Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

BreastDermatologicGastrointestinalGenitourinaryHead & NeckSarcomaThoracic

100 enrolled

Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Prostatic Neoplasms, Sarcoma, Skin Neoplasms, Urogenital Neoplasms

NCT03757091 2026-02-18

Flexible Intubation Scope With or Without Video Laryngoscope in Supporting Endotracheal Tube Placement in Patients With Head and Neck Cancer Before Surgery

Phase NA Completed

143 enrolled 10 charts

Phase 3 Active not recruiting

Head and Neck Neoplasms

NCT04967391 2026-02-18

Tumescence in HNC Skin Graft Reconstruction

58 enrolled

Phase 1/2 Active not recruiting

Head and Neck Neoplasms

NCT06237881 2026-02-18

A Phase 1/2 Study of KSQ-001EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate the SOCS1 Gene, in Patients With Select Advanced Solid Tumors

15 enrolled

DermatologicHead & NeckThoracic

Head and Neck Neoplasms, Lung Neoplasms, Melanoma

NCT07418034 2026-02-18

SAVED

Phase 2 Not yet recruiting

132 enrolled

GastrointestinalGynecologicHead & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Oropharyngeal Neoplasms, Papillomavirus Infections

NCT03065062 2026-02-13

Study of the CDK4/6 Inhibitor Palbociclib (PD-0332991) in Combination With the PI3K/mTOR Inhibitor Gedatolisib (PF-05212384) for Patients With Advanced Squamous Cell Lung, Pancreatic, Head & Neck and Other Solid Tumors

Phase 1 Suspended

75 enrolled

Head and Neck Neoplasms, Neoplasms, Pancreatic Neoplasms, Endometrial Neoplasms

NCT07110142 2026-02-13

T-PROSE

Phase NA Recruiting

40 enrolled