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1 trials

Recent Start date Enrollment

Phase 1 × Healthy Participants × sotorasib × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Conditions

Carcinoma, Non-Small-Cell Lung 5 Lung Neoplasms 2 Thoracic Neoplasms 1 Noonan Syndrome 1 Non-small Cell Lung Cancer Metastatic 1 Neoplasms 1 Neoplasm Metastasis 1 Healthy Participants 1 Advanced/Metastatic Solid Tumors With KRAS p.G12C Mutation 1 Advanced Solid Tumors 1 Advanced Solid Tumor 1 Advanced Non-small Cell Lung Cancer With KRAS G12C Mutation 1

Interventions

Rosuvastatin Calcium 5 capivasertib 2 Digoxin 2 sotorasib 1 ibrutinib 1 Midazolam 1 Dextromethorphan 1

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT05045638 2023-08-14

Effect of Coadministration of Sotorasib on the Pharmacokinetics of Rosuvastatin in Healthy Participants

Amgen

Phase 1 Completed

13 enrolled 14 charts

Healthy Participants

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