Clinical Trials

260 enrolled

Leukemia, Myeloid, Acute, Hematologic Neoplasms

NCT07220616 2026-03-18

A First-in-Human Trial of DS3790a in Participants With Hematological Malignancies

420 enrolled

Hematologic Neoplasms

NCT04588922 2026-03-16

Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Diagnosed AML

160 enrolled

Lymphoma, Recurrence, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Acute, Hematologic Neoplasms

NCT03145181 2026-03-12

MajesTEC-1

302 enrolled 1 FDA

Hematologic Neoplasms

NCT04565665 2026-03-10

Study of Cord Blood Derived Mesenchymal Stem Cells for Treatment of Moderate, Severe or Critical Pneumonia

70 enrolled

COVID-19, Hematologic Neoplasms

NCT05470491 2026-02-25

Trial of Allogeneic Reduced-Intensity, HLA-Haploidentical Allogeneic Hematopoietic Cell Bone Marrow Transplantation Followed by Graft-versus-Host-Disease (GVHD) Prophylaxis With Cyclophosphamide, Bortezomib and Maraviroc for Hematologic Malignancies ...

265 enrolled

Acquired Immunodeficiency Syndrome, Hematologic Neoplasms

NCT05428969 2026-02-20

BEXMAB

181 enrolled

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hematologic Neoplasms

NCT01203722 2026-02-19

Reduced Intensity, Partially HLA Mismatched BMT to Treat Hematologic Malignancies

Classical hematologyLymphoidOther hematologic neoplasm

87 enrolled 24 charts

Anemia, Refractory, with Excess of Blasts, Lymphoma, Hematologic Neoplasms

NCT07148180 2026-02-05

A Multi-Site Break Through Cancer Trial: Targeting Measurable Residual Disease in Patients With Acute Myeloid Leukemia: A Phase 1/2 Study of Tagraxofusp, Azacitidine, and Venetoclax

31 enrolled

Leukemia, Leukemia, Myeloid, Acute, Neoplasm, Residual, Hematologic Neoplasms

NCT05110742 2026-02-02

Phase I/II Study of CD5 CAR Engineered IL15-Transduced Cord Blood-Derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapsed/Refractory Hematological Malignances

64 enrolled

Hematologic Neoplasms

NCT04243499 2026-01-27

EVICTION

292 enrolled

Hematologic Neoplasms

NCT05327023 2026-01-26

Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies

430 enrolled

Bronchiolitis Obliterans Syndrome, Hematologic Neoplasms

NCT04959175 2026-01-21

Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies

320 enrolled

Bronchiolitis Obliterans Syndrome, Hematologic Neoplasms

NCT04379518 2026-01-13

Rintatolimod and IFN Alpha-2b for the Treatment of COVID-19 in Cancer Patients

4 enrolled 30 charts

Hematologic Neoplasms

NCT03983850 2025-12-26

Optimizing PTCy Dose and Timing

105 enrolled

Graft vs Host Disease, Hematologic Neoplasms

NCT04068597 2025-12-18

Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies

LymphoidOther hematologic neoplasmPlasma cell

250 enrolled

Lymphoma, Non-Hodgkin, Multiple Myeloma, Leukemia, Myeloid, Acute, Lymphoma, T-Cell, Peripheral, Hematologic Neoplasms

NCT06697184 2025-12-17

A Study to Investigate the Safety of Novel Dose Ramp-up Schedule(s) When Initiating Sonrotoclax in Participants Treated for Blood Cancers.

56 enrolled

Leukemia, Lymphocytic, Chronic, B-Cell, Hematologic Neoplasms

NCT05322850 2025-12-15

Phase I/II Trial: Engineered Donor Graft (Orca Q) for Pediatric Hematopoietic Cell Transplant (HCT)

40 enrolled

Disease, Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT04707300 2025-11-20

HTLP-ONCO

10 enrolled

Leukemia, Myeloid, Acute, Neoplasm, Residual, Hematologic Neoplasms

NCT04067336 2025-11-10

First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia

263 enrolled 1 FDA

Leukemia, Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT04874194 2025-11-03

Omacetaxine and Venetoclax for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome Harboring Mutant RUNX1

24 enrolled 15 charts

Myelodysplastic Syndromes, Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Acute, Hematologic Neoplasms

NCT03670966 2025-10-16

211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome

Classical hematologyLymphoidOther hematologic neoplasm

30 enrolled

Anemia, Refractory, with Excess of Blasts, Leukemia, Lymphoid, Leukemia, Monocytic, Acute, Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT06066203 2025-10-01

A Study of GNC-035 in Relapsed or Refractory Non-Hodgkin 's Lymphoma and Other Hematological Malignancies

40 enrolled

Lymphoma, Non-Hodgkin, Hematologic Neoplasms

NCT05944978 2025-09-26

A Study of GNC-035 in Relapsed or Refractory Chronic Lymphocytic Leukemia and Other Hematological Malignancies

3 enrolled

Phase 1/2 Not yet recruiting

Leukemia, Lymphocytic, Chronic, B-Cell, Hematologic Neoplasms

NCT07107204 2025-09-17

A Clinical Study of BT02 in Patients With Relapsed or Refractory Hematologic Malignancies

116 enrolled

LymphoidOther hematologic neoplasmPlasma cell

Leukemia, Lymphoma, Multiple Myeloma, Recurrence, Hematologic Neoplasms

NCT06948981 2025-09-16

GT719 Injection for the Treatment of Recurrent/Refractory CD19 Positive Adult B-cell Malignancies

46 enrolled

Hematologic Neoplasms

NCT03162536 2025-09-08

ARQ 531-101

LymphoidOther hematologic neoplasmPlasma cellSarcoma

190 enrolled

Blood Protein Disorders, Cardiovascular Diseases, Hemorrhagic Disorders, Immune System Diseases, Immunoproliferative Disorders, Leukemia, Leukemia, Lymphoid, Lymphatic Diseases, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Lymphoproliferative Disorders, Waldenstrom Macroglobulinemia, Neoplasms, Neoplasms by Histologic Type, Paraproteinemias, Recurrence, Vascular Diseases, Leukemia, B-Cell, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Hematologic Neoplasms, Hemostatic Disorders, Lymphoma, Mantle-Cell, Neoplasms, Plasma Cell, Dendritic Cell Sarcoma, Interdigitating

NCT02849886 2025-07-09

Side_by_Cide

2 enrolled

Graft vs Host Disease, Hematologic Neoplasms

NCT06119685 2025-06-03

IDP-023 as a Single Agent and in Combination With Antibody Therapies in Patients With Advanced Hematologic Cancers

LymphoidOther hematologic neoplasmPlasma cell

128 enrolled

Lymphoma, Non-Hodgkin, Multiple Myeloma, Hematologic Neoplasms

NCT01350258 2025-05-31

Bone Marrow Transplant Using a Reduced Intensity Regimen That is Given in Two Steps

LymphoidMyeloidOther hematologic neoplasmPlasma cell

8 enrolled 8 charts

Hodgkin Disease, Leukemia, Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Hematologic Neoplasms, Neoplasms, Plasma Cell

NCT02329847 2025-05-25

A Study to Evaluate Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of the Combination of Ibrutinib With Nivolumab in Participants With Hematologic Malignancies

144 enrolled 22 charts

Hematologic Neoplasms

NCT04752163 2025-05-23

DS-1594b With or Without Azacitidine, Venetoclax, or Mini-HCVD for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia

LymphoidMyeloidOther hematologic neoplasm

17 enrolled 15 charts

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT04730258 2025-05-18

TWT-202

72 enrolled

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hematologic Neoplasms

NCT03431090 2025-05-13

Haploidentical Hematopoietic Cell Transplantation for Children With Hematologic Malignancies and Myelodysplasia

Classical hematologyOther hematologic neoplasm

20 enrolled

Anemia, Refractory, with Excess of Blasts, Hematologic Neoplasms

NCT00429143 2025-05-04

A Two-Step Approach to Bone Marrow Transplant Using Cells From A Partially-Matched Relative

27 enrolled 11 charts

Hematologic Neoplasms

NCT01162096 2025-04-30

Reduced Intensity Haploidentical Transplant for Hematological Malignancies

34 enrolled 11 charts

Hematologic Neoplasms

NCT05943067 2025-04-27

CD45RADLIHaplo

60 enrolled

Hematologic Neoplasms

NCT01902173 2025-01-14

Uprosertib, Dabrafenib, and Trametinib in Treating Patients With Stage IIIC-IV Cancer

DermatologicOther hematologic neoplasm

27 enrolled 16 charts

Melanoma, Neoplasm Metastasis, Hematologic Neoplasms

NCT06720324 2024-12-06

CD7-specific CAR-T Cell in the Treatment of CD7-positive Relapsed/Refractory Hematologic Tumors

80 enrolled

Hematologic Neoplasms

NCT03648372 2024-11-19

A Study of TAK-981 in People With Advanced Solid Tumors or Cancers in the Immune System

109 enrolled 54 charts

Lymphoma, Neoplasms, Hematologic Neoplasms

NCT03837899 2024-10-29

Durvalumab and Tremelimumab for Pediatric Malignancies

50 enrolled 59 charts

Neoplasms, Hematologic Neoplasms

NCT01915498 2024-10-22

Phase 1/2 Study of Enasidenib (AG-221) in Adults With Advanced Hematologic Malignancies With an Isocitrate Dehydrogenase Isoform 2 (IDH2) Mutation

345 enrolled 120 charts 1 FDA

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Hematologic Neoplasms

NCT01664910 2024-07-23

CMC-544 and Allogeneic Transplantation for CD22 Positive-Lymphoid Malignancies

27 enrolled 12 charts

Hematologic Neoplasms

NCT03711604 2024-05-08

Compassionate Use Study of Tenalisib (RP6530)

17 enrolled 9 charts

Hematologic Neoplasms

NCT06206174 2024-04-10

TGRX-814 Chinese Phase I/II in Patients With Hematological Malignancies

LymphoidMyeloidOther hematologic neoplasm

30 enrolled

Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT06333509 2024-03-27

Anti-GPRC5D CAR-T Cells (CT071) in Participants With RRMM or RRpPCL

Phase 1/2 Not yet recruiting

166 enrolled

Other hematologic neoplasmPlasma cell

Multiple Myeloma, Hematologic Neoplasms

NCT01063647 2023-11-03

Dose-range Finding Treosulfan-based Conditioning

56 enrolled

Hematologic Neoplasms

NCT03733249 2023-09-26

Long Term Follow-up Study for Patients Enrolled on the BP-004 Clinical Study

Classical hematologyLymphoidMyeloidOther hematologic neoplasm

187 enrolled 8 charts

Primary Immunodeficiency Diseases, Cytopenia, Anemia, Anemia, Aplastic, Anemia, Sickle Cell, Fanconi Anemia, Hemoglobinopathies, Leukemia, Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Thalassemia, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Anemia, Diamond-Blackfan, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT05768035 2023-09-25

Safety and Efficacy of SMART101 in Adult Patients With Hematological Malignancies After Haploidentical HSCT With Post-transplant Cyclophosphamide

40 enrolled