Clinical Trials

600 enrolled

Hypoxia, Disease, Esophageal Neoplasms, Stomach Neoplasms, Sleep Apnea, Obstructive

NCT07063290 2026-02-24

COMBO Endoscopy Oropharyngeal Airway in Sedated Fiberoptic Bronchoscopy for Patients: A Simon Two-Stage Trial

104 enrolled

Hypoxia, Bronchiectasis

NCT07395596 2026-02-24

Remimazolam for Bronchoscopy in High-Risk Patients

Phase 4 Recruiting

360 enrolled

Hypoxia, Tuberculosis, Pulmonary

NCT06685848 2026-01-07

Comparison of Hemanext ONE® System and Conventional Red Blood Cell Transfusion

Other hematologic neoplasm

24 enrolled

Hypoxia, Hematologic Neoplasms

NCT04266665 2025-11-28

Effect of Dexmedetomidine on Brain Homeostasis and Neurocognitive Outcome

Phase 4 Completed

56 enrolled

Neuroinflammatory Diseases, Hypoxia, Brain Neoplasms

NCT07155330 2025-11-25

High-flow Nasal Cannula Oxygenation in Sedated Endoscopy for High-risk Obstructive Sleep Apnea Patients

80 enrolled

Hypoxia, Colonic Neoplasms, Disease, Esophageal Neoplasms, Stomach Neoplasms, Sleep Apnea, Obstructive

NCT05119335 2025-11-12

A Study of NKT2152, a HIF2α Inhibitor, in Patients With Advanced Clear Cell Renal Cell Carcinoma

Phase 1/2 Terminated

120 enrolled

Genitourinary

Hypoxia, Carcinoma, Renal Cell, Kidney Neoplasms

NCT06796764 2025-09-10

COMBO Endoscopy Oropharyngeal Airway Reduces Hypoxia During Sedated Gastrointestinal Endoscopy in Obese Patients: A Multicenter, Randomized, Controlled Clinical Trial

580 enrolled

Hypoxia, Esophageal Neoplasms, Stomach Neoplasms

NCT06832683 2025-09-10

Efficacy of Propofol-Ketamine and Sevoflurane in Children Undergoing Magnetic Resonance Imaging

230 enrolled

Lymphoid

Hypoxia, Lymphoma, Follicular

NCT06081647 2025-06-25

The Efficacy and Safety of the COMBO Endoscopy Oropharyngeal Airway in Gastrointestinal Endoscopy Procedure

1,200 enrolled

Polyposis, Gastric, Hypoxia, Colonic Neoplasms, Esophageal Neoplasms

NCT06812403 2025-06-25

Combination COMBO Endoscopy Oropharyngeal Airway With High-Flow Nasal Cannula Oxygenation in Sedated Gastrointestinal Endoscopy for Obese Patients

50 enrolled

Hypoxia, Colonic Polyps, Esophageal Neoplasms, Stomach Neoplasms

NCT06205927 2025-06-17

Randomized Study of Carbon Ion Boost in Hypoxic Lesions for Locally Advanced Non-small Cell Lung Cancer

Phase 2 Recruiting

77 enrolled

Hypoxia, Carcinoma, Non-Small-Cell Lung

NCT05405530 2025-06-05

NASO

1,204 enrolled

Polyposis, Gastric, Hypoxia, Colonic Neoplasms, Colonic Polyps, Esophageal Neoplasms, Stomach Neoplasms

NCT06804876 2025-05-21

COMBO Endoscopy Oropharyngeal Airway in Sedated Gastrointestinal Endoscopy for Obese Patients

107 enrolled

Phase NA Active not recruiting

Hypoxia, Colonic Neoplasms, Esophageal Neoplasms, Stomach Neoplasms

NCT03168815 2025-05-09

Low-Flow vs. High-Flow Nasal Cannula for Hypoxemic Immunocompromised Patients During Diagnostic Bronchoscopy

98 enrolled

Other hematologic neoplasm

Hypoxia, Hematologic Neoplasms

NCT05348486 2025-04-22

FARHEAD

120 enrolled

Phase 1/2 Not yet recruiting

Hypoxia, Head and Neck Neoplasms

NCT06939270 2025-04-22

CD73/AXL Targeted HypoSti.CAR-T Cells in CD73/AXL Positive Advanced/Metastatic Solid Tumors

30 enrolled

Hypoxia

NCT06476704 2025-02-04

PRACTISS

Phase 2 Not yet recruiting

42 enrolled

Sarcoma

Hypoxia, Sarcoma

NCT02174549 2024-11-22

Dose-defining Study of Tirapazamine Combined With Embolization in Liver Cancer

Phase 1/2 Recruiting

25 enrolled

EndocrineGastrointestinalNET

Hypoxia, Carcinoma, Hepatocellular, Neuroendocrine Tumors

NCT06477939 2024-06-27

THREE-GLEES

Phase 3 Not yet recruiting

554 enrolled

Hypoxia, Brain Neoplasms, Glioblastoma

NCT04995185 2024-05-16

18F-FMISO PET Guided Dose Escalation in Nasopharyngeal Carcinoma - a Feasibility and Planning Study

9 enrolled

Nasopharyngeal Carcinoma, Hypoxia, Nasopharyngeal Neoplasms

NCT05030870 2024-03-19

CapnoGI

1,800 enrolled

Polyposis, Gastric, Hypoxia, Colonic Neoplasms, Colonic Polyps, Esophageal Neoplasms, Stomach Neoplasms

NCT04500392 2024-01-11

High-flow Nasal Cannula Oxygenation Decrease Hypoxia in Sedated Gastrointestinal Endoscopes in Obesity

1,000 enrolled

Hypoxia, Colonic Neoplasms, Colonic Polyps, Esophageal Neoplasms, Stomach Neoplasms

NCT02706197 2023-09-21

Oxygen Measurements in Subcutaneous Tumors by EPR Oximetry Using OxyChip

Phase NA Terminated

25 enrolled 9 charts

Hypoxia, Neoplasms

NCT01827709 2023-04-03

Pathological Validation of Functional Imaging in Head and Neck Squamous Cell Carcinoma

Phase NA Terminated

11 enrolled

Squamous Cell Carcinoma of Head and Neck, Hypoxia, Head and Neck Neoplasms

NCT02454842 2023-01-12

TH-4000

21 enrolled

Hypoxia, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell

NCT03365076 2023-01-09

EXIPOX

Phase NA Terminated

1 enrolled

Genitourinary

Hypoxia, Motor Activity, Prostatic Neoplasms

NCT04727034 2022-10-12

Efficacy and Safety of Remimazolam Tosylate for Sedation in Gastroscopy

1,800 enrolled

Hypoxia, Stomach Neoplasms

NCT04566419 2022-09-16

SAMURAI

80 enrolled

Hypoxia, Pulmonary Atelectasis, Postoperative Complications

NCT05526339 2022-09-02

HFNO Combined With NPA Reduces Hypoxia During Sedated Gastrointestinal Endoscopy In Obese Patients

600 enrolled

Hypoxia, Intestinal Neoplasms, Intestinal Polyps, Stomach Neoplasms, Stomach Ulcer

NCT05510388 2022-08-22

HRISK

450 enrolled

Hypoxia, Gastritis, Intestinal Neoplasms, Stomach Neoplasms

NCT00980759 2021-09-08

Prophylactic Irradiation of the Para-Aortic Lymph Nodes in Locally Advanced Uterine Cervical Cancer

312 enrolled

Gynecologic

Hypoxia, Uterine Cervical Neoplasms

NCT02661152 2021-04-13

DAHANCA30

Phase 3 Unknown

1,252 enrolled

Squamous Cell Carcinoma of Head and Neck, Hypoxia

NCT02490696 2020-07-30

RTEP6

23 enrolled

Hypoxia, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03547388 2020-05-05

GKH-TMM

Phase 1 Completed

10 enrolled

Phase EARLY_PHASE1 Completed

Squamous Cell Carcinoma of Head and Neck, Hyperthermia, Hypoxia, Head and Neck Neoplasms, Recurrence

NCT01924689 2019-09-09

Safety Study of Intratumoral Injection of Clostridium Novyi-NT Spores to Treat Patients With Solid Tumors That Have Not Responded to Standard Therapies

Phase 1 Completed

24 enrolled 18 charts

Sarcoma

Hypoxia, Chordoma, Necrosis, Neoplasm Metastasis, Neoplasms, Sarcoma

NCT02628080 2019-09-04

ATOM

46 enrolled

Hypoxia, Carcinoma, Non-Small-Cell Lung

NCT04001023 2019-08-07

OVANOX

40 enrolled

Gynecologic

Carcinoma, Ovarian Epithelial, Hypoxia, Fallopian Tube Neoplasms

NCT02233387 2019-03-08

HX4-cervix

4 enrolled

Gynecologic

Hypoxia, Uterine Cervical Neoplasms

NCT02584400 2019-03-08

HX4 SD

CNSGastrointestinalGenitourinary

1 enrolled

Hypoxia, Brain Neoplasms, Esophageal Neoplasms, Neoplasm Metastasis, Prostatic Neoplasms, Rectal Neoplasms

NCT01210378 2019-02-15

Nitroglycerin

47 enrolled

Hypoxia, Carcinoma, Non-Small-Cell Lung

NCT02976883 2019-01-11

OXYPET

8 enrolled

Head & NeckThoracic

Hypoxia, Head and Neck Neoplasms, Lung Neoplasms

NCT03716986 2018-10-23

GLIOXYMAGE

20 enrolled

Hypoxia, Glioma

NCT03332433 2018-09-05

HONCHO

2,034 enrolled

Phase EARLY_PHASE1 Completed

Hypoxia, Esophageal Neoplasms, Stomach Neoplasms

NCT02466828 2018-04-18

qBOLD MRI of Glioblastoma Multiforme for Assessment of Tumor Hypoxia.

10 enrolled

Hypoxia, Glioblastoma

NCT03040570 2018-02-23

Oxy-PICU

LymphoidOther hematologic neoplasm

120 enrolled

Hypoxia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02496832 2018-02-19

A Study of Hypoxia Imaging in Advanced Pancreatic Cancer Patients Being Treated With Gemcitabine and TH-302 or TH-302 Placebo

Phase NA Withdrawn

Hypoxia, Neoplasm Metastasis

NCT03098160 2017-10-30

Immunotherapy Study of Evofosfamide in Combination With Ipilimumab

Phase 1 Unknown

69 enrolled

DermatologicGastrointestinalGenitourinaryHead & Neck

Squamous Cell Carcinoma of Head and Neck, Hypoxia, Melanoma, Pancreatic Neoplasms, Prostatic Neoplasms

NCT02157246 2017-03-13

RHYTHM-I

14 enrolled