Clinical Trials

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT03082534 2026-01-28

Pembrolizumab Combined With Cetuximab for Treatment of Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma

78 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Neoplasm Metastasis, Oropharyngeal Neoplasms, Recurrence

NCT05406024 2025-12-11

FAISA-CORPPS

GastrointestinalHead & Neck

Esophageal Neoplasms, Laryngeal Neoplasms, Neoplasms

NCT07241611 2025-11-21

Role of Cervical Fascia Flap in Decreasing the Incidence of Pharyngocutaneous Fistula After Total Laryngectomy

50 enrolled

Laryngeal Neoplasms

NCT02918955 2025-11-20

UPFRONT-NECK

Phase 3 Completed

65 enrolled

Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Oropharyngeal Neoplasms

NCT01257633 2025-11-17

Surgical Treatment of Early Stage Glotto-supraglottic Laryngeal Cancer Via Transoral Resection With Robotic Assistance

54 enrolled

Laryngeal Neoplasms

NCT06129487 2025-11-14

Evaluations of Alcohol Warning Labels

GastrointestinalHead & Neck

1,053 enrolled 15 charts

Alcohol Drinking, Esophageal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms

NCT02586207 2025-10-07

Pembrolizumab in Combination With CRT for LA-SCCHN

59 enrolled 9 charts

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Diseases, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT04788264 2025-05-22

Exercise Training and Behavioral Modification for the Improvement of Physical Activity in Head and Neck Cancer Patients Undergoing Cancer Treatment

12 enrolled

Head & NeckThoracic

Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Lung Neoplasms, Maxillary Sinus Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms, Paranasal Sinus Neoplasms

NCT05346237 2025-05-06

Validation and Cross-cultural Adaptation of Croatian SECEL Questionnaire

50 enrolled 12 charts

Communication, Laryngeal Neoplasms, Speech

NCT05349487 2025-02-03

SPEAKFREE

18 enrolled

GastrointestinalHead & Neck

Laryngeal Neoplasms

NCT05369234 2024-10-10

Effects of Oral Aloe Vera Juice on Chemotherapy and Radiation-induced Oral Mucositis and Esophagitis

Phase 3 Completed

100 enrolled

Esophageal Neoplasms, Laryngeal Neoplasms, Mediastinal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT03028766 2024-09-19

WISTERIA

9 enrolled

Squamous Cell Carcinoma of Head and Neck, Laryngeal Neoplasms

NCT03329950 2024-03-28

A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignancies

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidThoracic

132 enrolled

Bile Duct Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Esophageal Neoplasms, Fallopian Tube Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Laryngeal Neoplasms, Liver Neoplasms, Lung Neoplasms, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Melanoma, Mouth Neoplasms, Oropharyngeal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Lymphoma, Large B-Cell, Diffuse, Cholangiocarcinoma, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Hyper-IgM Immunodeficiency Syndrome

NCT03653039 2024-02-29

Tritube

48 enrolled

Laryngeal Neoplasms, Mouth Neoplasms, Pharyngeal Neoplasms

NCT06256263 2024-02-13

Stapler Versus Conventional Pharyngeal Repair After Total Larygectomy

58 enrolled

Laryngeal Neoplasms

NCT02757222 2023-12-28

INTELHOPE

100 enrolled

Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Oropharyngeal Neoplasms

NCT01332682 2023-10-18

Resistance Training and Physical Functioning in Head and Neck Cancer Patients

18 enrolled

Head and Neck Neoplasms, Laryngeal Neoplasms, Pharyngeal Neoplasms

NCT05217147 2023-09-22

An Investigation of Biomarker Candidate Molecules in Laryngeal Carcinoma

80 enrolled

Laryngeal Neoplasms

NCT03602079 2023-08-03

Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

49 enrolled

Bile Duct Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Colonic Neoplasms, Head and Neck Neoplasms, Laryngeal Neoplasms, Lip Neoplasms, Liver Neoplasms, Lung Neoplasms, Mouth Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Salivary Gland Neoplasms, Skin Neoplasms, Stomach Neoplasms, Tongue Neoplasms, Tonsillar Neoplasms, Urologic Neoplasms, Carcinoma, Mucoepidermoid, Cholangiocarcinoma, Rare Diseases

NCT00743262 2023-07-25

Short-term Clinical Feasibility of the New Provox Vega 22.5 Voice Prosthesis

15 enrolled 7 charts

Laryngeal Neoplasms

NCT02198131 2023-04-26

Pulsed Dye Laser in Treating Patients With Post Radiation Dysphonia

9 enrolled

Laryngeal Neoplasms

NCT05746780 2023-02-28

Bilateral Elective Neck Dissection in Salvage Total Laryngectomy

80 enrolled

Head and Neck Neoplasms, Laryngeal Diseases, Laryngeal Neoplasms

NCT01984502 2022-06-30

CyberKnife Accelerated Hemilarynx Stereotactic Radiotherapy Study for Early-stage Glottic Larynx Cancer

Laryngeal Neoplasms

NCT00765791 2022-06-09

2BN2B

40 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT00530049 2021-12-21

Measuring Patient Satisfaction With Facial Appearance: Development and Validation of a New Patient-Reported Outcome Measure

1,745 enrolled

Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Salivary Gland Neoplasms, Tongue Neoplasms

NCT03096808 2021-10-26

Adaptive Radiotherapy for Head and Neck Cancer

64 enrolled

Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Paranasal Sinus Neoplasms

NCT01084733 2021-07-14

Nicotine Levels With Response Rates to Radiation Alone or With Chemo In Head & Neck Cancer

115 enrolled

Laryngeal Neoplasms, Lip Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms, Pharyngeal Neoplasms

NCT01045057 2021-06-11

Clinical Feasibility of New Tracheoesophageal Puncture Set

27 enrolled 9 charts

Laryngeal Neoplasms

NCT04458818 2021-04-29

A Novel Approach for Thyroplasty Type 1, With Prolene Mesh. A Prospective Study.

39 enrolled 6 charts

Laryngeal Neoplasms, Vocal Cord Paralysis

NCT04778306 2021-03-03

Transoral Laser Surgery and Radiotheraphy for Early Stage Laryngeal Squamous Cell Cancer

261 enrolled

Laryngeal Neoplasms

NCT03292341 2020-11-30

LaDecA

9 enrolled

Laryngeal Neoplasms

NCT02739958 2020-09-22

Effects of Propofol-dexmedetomidine on Immune Function in Patients With Cancer Larynx

40 enrolled

Laryngeal Neoplasms

NCT04525066 2020-08-25

Phonosurgical Augmentation After Laser Resection of Early Glottic Carcinoma

39 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Laryngeal Neoplasms, Voice Disorders

NCT00833261 2020-08-21

Nab-Paclitaxel, Cetuximab, Cisplatin, and Radiation Therapy in Treating Patients With Recurrent Head and Neck Cancer

37 enrolled 6 charts

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Tongue Neoplasms, Carcinoma, Verrucous

NCT03132727 2020-04-03

Larynx MRI

73 enrolled

Hypopharyngeal Neoplasms, Laryngeal Neoplasms

NCT00524017 2020-03-12

Cetuximab in Treating Patients With Precancerous Lesions of the Upper Aerodigestive Tract

Head & NeckOther neoplasm

35 enrolled 6 charts

Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Precancerous Conditions, Salivary Gland Neoplasms

NCT01469429 2020-02-20

Phase 1b Food Based Modulation of Biomarkers in Human Tissues at High-Risk for Oral Cancer.

70 enrolled

Squamous Cell Carcinoma of Head and Neck, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Paranasal Sinus Neoplasms, Salivary Gland Neoplasms, Tongue Neoplasms

NCT01445405 2019-12-17

Radiation Therapy and Bortezomib and Cetuximab With or Without Cisplatin to Treat Head and Neck Cancer

3 enrolled

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Pharyngeal Neoplasms

NCT00656513 2019-11-19

Acupuncture-Like Transcutaneous Electrical Nerve Stimulation (ALTENS) or Pilocarpine in Treating Early Dry Mouth in Patients Undergoing Radiation Therapy for Head and Neck Cancer

Phase 2/3 Completed

196 enrolled 13 charts

Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Salivary Gland Neoplasms, Tongue Neoplasms, Xerostomia

NCT01806675 2019-10-03

18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy

BreastCNSGastrointestinalGenitourinaryHead & NeckSarcomaThoracic

25 enrolled 14 charts

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colonic Neoplasms, Glioblastoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Salivary Gland Neoplasms, Tongue Neoplasms, Esthesioneuroblastoma, Olfactory, Gliosarcoma, Breast Neoplasms, Male

NCT02849314 2019-09-12

Combination of Cryosurgey and NK Immunotherapy for Recurrent Laryngeal Cancer

Laryngeal Neoplasms

NCT00721799 2019-08-06

F-18 Fluorothymidine PET Imaging for Early Evaluation of Response to Therapy in Head & Neck Cancer Patients

33 enrolled 39 charts

Head and Neck Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT02587546 2019-08-01

Thulium Contact Laser of Laryngotracheal Stenosis

31 enrolled

Laryngeal Neoplasms, Vocal Cord Paralysis

NCT00978081 2019-04-23

Photodynamic Therapy in Treating Patients With Premalignant or Early Stage Head and Neck Tumors

Head & NeckOther neoplasm

35 enrolled

Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Precancerous Conditions

NCT00534729 2019-03-01

Organ Preservation: Weekly Carboplatin & Taxol w/Concurrent RT for Locally Advanced Laryngeal & Hypopharyngeal CA

200 enrolled

Hypopharyngeal Neoplasms, Laryngeal Diseases, Laryngeal Neoplasms

NCT00169182 2019-02-15

Induction CT by Cisplatin, 5FU With or Without Docetaxel in Patients With T3 and T4 Larynx and Hypopharynx Carcinoma

Phase 3 Completed

220 enrolled

Hypopharyngeal Neoplasms, Laryngeal Neoplasms

NCT03585075 2018-07-12

FLUOROCORD

Laryngeal Neoplasms

NCT02156518 2018-05-08

The Efficacy of Vocal Function Exercises for Laryngeal Cancers

12 enrolled