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Phase 3 × Leiomyoma × Clear all

NCT06671548 2026-02-02

Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Phase 3 Recruiting

Leiomyoma, Menorrhagia

NCT07378098 2026-01-30

to Evaluate the Efficacy and Safety of KLH-2109 in Patients With Uterine Fibroids and Menorrhagia

Phase 3 Recruiting

Leiomyoma, Menorrhagia

NCT04756037 2026-01-08

SERENE

Phase 3 Active not recruiting

Endometriosis, Leiomyoma

NCT04655144 2026-01-07

Dex-Fib

Phase 3 Completed

42 enrolled 9 charts

Leiomyoma

NCT05445167 2025-11-25

A Clinical Study of KLH-2109 in Uterine Fibroids Patient With Menorrhagia and Pain

Phase 3 Completed

Leiomyoma

NCT05862272 2025-08-06

A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis

Phase 3 Recruiting

Endometriosis, Leiomyoma, Myofibroma

NCT03194646 2025-07-28

ASTEROID 6

Phase 3 Terminated

1,272 enrolled 16 charts

Leiomyoma

NCT05364008 2025-07-25

FRIEND

Phase 3 Recruiting

Leiomyoma

NCT03271489 2025-07-22

Long-Term Safety Study of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women

Phase 3 Completed

478 enrolled 9 charts

Leiomyoma, Menorrhagia

NCT05440383 2025-03-14

A Clinical Study of KLH-2109 in Uterine Fibroids Patient With Menorrhagia

Phase 3 Completed

Leiomyoma

NCT03948789 2024-11-13

Phase III Study of MR-Guided Focused Ultrasound Surgery for the Treatment of Uterine Fibroids Compared to Myomectomy

Phase 3 Active not recruiting

Leiomyoma

NCT03240523 2024-10-18

ASTEROID 5

Phase 3 Terminated

Leiomyoma

NCT04849858 2024-08-23

Pilot Study of Liposomal Bupivacaine Redosing in Patients Undergoing Major Gynecologic Procedures

Phase 3 Terminated

Leiomyoma, Ovarian Neoplasms, Uterine Neoplasms

NCT03751124 2024-06-25

Study of Relugolix With Estradiol and Norethindrone Acetate in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Phase 3 Completed

229 enrolled 66 charts

Leiomyoma, Menorrhagia, Myofibroma

NCT00133705 2023-09-25

Trial of Mifepristone for Fibroids

Phase 3 Completed

70 enrolled 6 charts

Leiomyoma

NCT04311073 2023-09-11

Prophylactic Tranexamic Acid During Minimally Invasive Myomectomies

Phase 3 Unknown

Leiomyoma, Metrorrhagia, Myofibroma

NCT03400943 2023-05-03

Assess Safety and Efficacy of Vilaprisan in Subjects With Uterine Fibroids (ASTEROID 3)

Phase 3 Terminated

93 enrolled 19 charts

Leiomyoma, Menorrhagia

NCT05620355 2023-03-21

Efficacy and Safety of BG2109 in Subjects With Heavy Menstrual Bleeding Associated With Uterine Fibroids.

Phase 3 Unknown

Leiomyoma, Menorrhagia

NCT03476928 2022-07-08

ASTEROID 8

Phase 3 Terminated

Leiomyoma, Menorrhagia

NCT03400956 2022-06-30

Assess Safety and Efficacy of Vilaprisan in Subjects With Uterine Fibroids (ASTEROID 4)

Phase 3 Terminated

103 enrolled 18 charts

Leiomyoma, Menorrhagia

NCT03103087 2022-04-20

LIBERTY 2: Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Phase 3 Completed

382 enrolled 57 charts

Leiomyoma, Menorrhagia

NCT02691494 2021-07-13

Efficacy and Safety of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women (Replicate Study)

Phase 3 Completed

378 enrolled 16 charts

Leiomyoma, Menorrhagia

NCT02925494 2021-07-13

An Extension Study to Evaluate the Efficacy and Safety of Elagolix in Premenopausal Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Phase 3 Completed

433 enrolled 16 charts

Leiomyoma, Menorrhagia

NCT03070951 2021-03-05

PRIMROSE 2

Phase 3 Completed

Leiomyoma, Menorrhagia

NCT02189083 2020-10-28

Study of Tumor-shrinking Decoction (TSD) to Treat Symptomatic Uterine Fibroids

Phase 3 Completed

Leiomyoma

NCT02425878 2020-10-14

Ulipristal Acetate 10 mg and Asisted Reproduction

Phase 3 Terminated

Leiomyoma

NCT02654054 2020-06-29

Efficacy and Safety of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women

Phase 3 Completed

413 enrolled 16 charts

Leiomyoma, Menorrhagia

NCT03699176 2020-01-18

ASTEROID 7

Phase 3 Withdrawn

Leiomyoma

NCT02147197 2019-04-30

A Study of the Efficacy and Safety of a 3-month Treatment Course of Ulipristal Acetate for the Treatment of Abnormal Uterine Bleeding Associated With Leiomyomas

Phase 3 Completed

157 enrolled 11 charts

Leiomyoma, Uterine Hemorrhage

NCT02655224 2019-03-22

A Placebo-Controlled, Phase 3 Study of Relugolix (TAK-385) 40 mg in the Treatment of Pain Symptoms Associated With Uterine Fibroids

Phase 3 Completed

65 enrolled 28 charts

Leiomyoma

NCT00295217 2018-12-20

MR Guided Focused Ultrasound Surgery in the Treatment of Uterine Fibroids: Software V4.2 Validation

Phase 3 Completed

Leiomyoma, Myofibroma

NCT03122782 2017-06-29

Hemostatic Effect of Intrauterine Instillation Of Tranexamic Acid In Hysteroscopic Myomectomy

Phase 3 Unknown

Leiomyoma, Blood Loss, Surgical

NCT01156857 2016-01-15

PEARLIII

Phase 3 Completed

Leiomyoma

NCT01252069 2016-01-13

PGL4001 Efficacy Assessment in Reduction of Symptoms Due to Uterine Leiomyomata (PEARLIII-extension Study)

Phase 3 Completed

Leiomyoma

NCT01642472 2016-01-08

PEARLext2

Phase 3 Completed

Leiomyoma

NCT00737282 2014-08-21

Multicenter Study Evaluating the Safety of Proellex® in Premenopausal Women With Uterine Fibroids

Phase 3 Terminated

175 enrolled 1 chart

Leiomyoma

NCT00785356 2014-08-21

Safety and Efficacy of Proellex in Pre-Menopausal Anemic Women With Symptomatic Uterine Fibroids

Phase 3 Terminated

8 enrolled 1 chart

Classical hematology

Anemia, Leiomyoma

NCT00853567 2014-08-21

Evaluating the Safety and Efficacy of Proellex® in Premenopausal Women With Symptomatic Uterine Fibroids

Phase 3 Terminated

71 enrolled 1 chart

Leiomyoma

NCT01069120 2014-08-21

Safety of 25 and 50 mg Proellex® in the Treatment of Women With Symptomatic Uterine Fibroids

Phase 3 Terminated

27 enrolled 1 chart

Leiomyoma

NCT02061657 2014-08-12

Impact of Misoprostol on Blood Loss In Myomectomy Operations

Phase 3 Completed

Leiomyoma

NCT00874302 2014-06-27

Safety and Efficacy of 25 and 50 mg Doses of Proellex® in Treating the Recurrence of Uterine Fibroid Symptoms

Phase 3 Withdrawn

Leiomyoma

NCT01553123 2013-02-07

Efficacy and Safety Study of Ulipristal Acetate in Females With Anemia Associated With Uterine Leiomyoma

Phase 3 Withdrawn

Leiomyoma

NCT01064960 2012-12-04

Therapeutic MRI-HIFU Ablation of Uterine Fibroids in a 3T MRI Scanner

Phase 3 Completed

Connective Tissue Diseases, Leiomyoma, Neoplasms, Neoplasms by Histologic Type, Neoplasms, Connective Tissue, Neoplasms, Muscle Tissue, Neoplasms, Connective and Soft Tissue, Myofibroma

NCT01141062 2012-12-04

HIFU

Phase 3 Completed

Leiomyoma, Myofibroma

NCT01581944 2012-04-20

Gonadotropin-releasing Hormone Agonist Prior to Myomectomy

Phase 3 Completed

Hemorrhage, Leiomyoma

NCT00152256 2008-05-29

A Study to Evaluate of the Safety and Effectiveness of Asoprisnil in Treating Women With Uterine Fibroids

Phase 3 Completed

Leiomyoma, Menorrhagia, Metrorrhagia, Uterine Hemorrhage

NCT00152269 2008-05-29

Treatment of Uterine Fibroids With Asoprisnil(J867)

Phase 3 Completed

Leiomyoma, Menorrhagia, Metrorrhagia, Uterine Hemorrhage

NCT00156195 2008-05-29

Study to Evaluate the Safety of Asoprisnil in the Treatment of Uterine Fibroids

Phase 3 Completed

Leiomyoma, Menorrhagia, Metrorrhagia, Uterine Hemorrhage

NCT00156208 2008-05-29

Safety of Treatment of Uterine Fibroids With Asoprisnil

Phase 3 Completed

Leiomyoma, Menorrhagia, Metrorrhagia, Uterine Hemorrhage

NCT00160381 2008-05-29

A Study to Evaluate the Safety and Effectiveness of Asoprisnil in the Treatment of Uterine Fibroids

Phase 3 Completed

Leiomyoma, Menorrhagia, Metrorrhagia, Uterine Hemorrhage