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Phase EARLY_PHASE1 × Leukemia, Large Granular Lymphocytic × siltuximab × Clear all

Phase

Phase EARLY_PHASE1 1

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1

Conditions

Thrombocytosis 1 Thrombocytopenia 1 Primary Myelofibrosis 1 Polycythemia Vera 1 Lymphoma, Follicular 1 Leukemia, Large Granular Lymphocytic 1 Anemia 1

Interventions

siltuximab 1 calaspargase pegol 1 Prednisone 1 Pemetrexed 1 Methotrexate 1 Interleukin-6 1 Ifosfamide 1 Etoposide 1 Doxorubicin 1 Dexamethasone 1 Cyclophosphamide 1 Brentuximab Vedotin 1

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT05316116 2026-02-05

Siltuximab in Large Granular Lymphocytic Leukemia (LGLL)

H. Lee Moffitt Cancer Center and Research Institute

Phase EARLY_PHASE1 Terminated

Other hematologic neoplasm

Leukemia, Large Granular Lymphocytic

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