Clinical Trials

Leukemia, Myeloid, Acute

NCT04708054 2026-02-19

Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With High-Risk AML and MDS

324 enrolled

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic

NCT07366801 2026-01-26

Co-infusion of Treg-enriched Donor Lymphocytes With CD3-depleted Hematopoietic Stem Cell Graft to Prevent Graft-versus Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation Among Children With Hematologic Malignancies

LymphoidOther hematologic neoplasm

64 enrolled

Recurrence, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03701308 2026-01-21

Daunorubicin and Cytarabine With or Without Uproleselan in Treating Older Adult Patients With Acute Myeloid Leukemia Receiving Intensive Induction Chemotherapy

Phase 2/3 Active not recruiting

267 enrolled 11 charts

Leukemia, Myeloid, Acute

NCT06788756 2025-12-16

L-Annamycin for Injection in Combination With Cytarabine Injection as Second Line Therapy for Remission Induction in Adult Subjects With Refractory/Relapsed AML

312 enrolled

Phase 2/3 Not yet recruiting

Leukemia, Myeloid, Acute

NCT07264010 2025-12-04

Sorafenib Combined With Venetoclax as Pre-emptive Therapy Strategy for MRD+ AML: a Prospective, Single-arm, Multicenter Clinical Study

87 enrolled

Phase 2/3 Active not recruiting

Leukemia, Myeloid, Acute, Neoplasm, Residual

NCT05356169 2025-05-30

Intensive Therapy Combined With Venetoclax for Adult Acute Myeloid Leukemia

312 enrolled

Leukemia, Myeloid, Acute

NCT00179829 2025-02-04

WT1 for the Detection of Minimal Residual Disease

50 enrolled

Leukemia, Neoplasms, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03092674 2025-01-16

Azacitidine With or Without Nivolumab or Midostaurin, or Decitabine and Cytarabine Alone in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

76 enrolled 16 charts

Phase 2/3 Active not recruiting

GATA2 Deficiency, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT06475820 2024-08-23

Preventing of GVHD With Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Baricitinib at Children and Young Adults With Hemoblastosis

150 enrolled

Graft vs Host Disease, Lymphoma, Myelodysplastic Syndromes, Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02416388 2024-08-07

BIG-1

3,100 enrolled

Leukemia, Myeloid, Acute

NCT01751997 2024-04-19

Family-mismatched/Haploidentical Donors Versus Matched Unrelated Donors

116 enrolled

Leukemia, Myeloid, Acute

NCT05939180 2024-04-09

VA vs DA for Newly Diagnosed Hig-risk AML

116 enrolled

Leukemia, Myeloid, Acute

NCT06285136 2024-02-29

Safety and Efficacy of Venetoclax Combination With Decitabine(DEC3-VEN) in the Treatment of AML in the Adult

40 enrolled

Leukemia, Myeloid, Acute

NCT02473146 2024-02-02

ALFA1401

225 enrolled

Leukemia, Myeloid, Acute

NCT04257175 2023-11-28

CAR-T CD19 for Acute Myelogenous Leukemia With t 8:21 and CD19 Expression

10 enrolled

Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Acute

NCT03699475 2023-09-29

THRIVE

Phase 2/3 Terminated

1 enrolled 9 charts

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT00413439 2023-05-10

Safety, Efficacy and Pharmacokinetics of an Antifungal in Patients Undergoing Chemotherapy

18 enrolled

Leukemia, Myeloid, Acute

NCT04217278 2023-05-10

COSI

333 enrolled

Leukemia, Myeloid, Acute

NCT05805098 2023-04-07

VHA

60 enrolled

Leukemia, Myeloid, Acute

NCT00354120 2023-03-10

GLOBAL

Classical hematologyLymphoidMyeloidOther hematologic neoplasm

121 enrolled

Anemia, Refractory, with Excess of Blasts, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Primary Myelofibrosis

NCT05404906 2022-08-19

AZA + Venetoclax as Maintenance Therapy in Younger Adults With AML in First Remission

124 enrolled

Leukemia, Myeloid, Acute

NCT05175508 2022-01-03

Aza With or Without ATRA in Newly Diagnosed Unfit AML or Intermediate,High or Very High Risk MDS

180 enrolled

Frailty, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Hematologic Neoplasms

NCT00003816 2021-08-13

Combination Chemotherapy and Donor Stem Cell Transplant in Treating Patients With Aplastic Anemia or Hematologic Cancer

Classical hematologyDermatologicLymphoidMyeloidOther hematologic neoplasmSarcoma

361 enrolled 16 charts

Congenital Abnormalities, Anemia, Aplastic, Anemia, Refractory, Anemia, Refractory, with Excess of Blasts, Blast Crisis, Burkitt Lymphoma, Immunoblastic Lymphadenopathy, Leukemia, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Mycosis Fungoides, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasms, Polycythemia Vera, Sezary Syndrome, Thrombocythemia, Essential, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Biphenotypic, Acute, Leukemia, Prolymphocytic, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Dendritic Cell Sarcoma, Interdigitating, Primary Myelofibrosis, Intraocular Lymphoma

NCT03530085 2020-12-22

Dec+Flu+Bu Conditioning Regimen for Elderly AML in CR Undergoing Allo-HSCT

60 enrolled

Leukemia, Myeloid, Acute

NCT03793517 2020-03-10

Decitabine Plus mBU/CY for High Risk Acute Leukemia With MRD Pre-HSCT

55 enrolled

Leukemia, Myeloid, Acute

NCT02870777 2020-03-04

MRD-directed Therapy for Low-risk and Intermediate-risk AML.

743 enrolled

Leukemia, Myeloid, Acute, Neoplasm, Residual

NCT02671708 2020-03-03

IDA+BUCY vs BUCY Conditioning Regimen for Intermediate-risk AML Undergoing Auto-HSCT

153 enrolled

Leukemia, Myeloid, Acute

NCT00952588 2020-02-24

SPARK-AML1

74 enrolled 13 charts

Leukemia, Myeloid, Acute

NCT02272478 2020-01-23

AML18

1,600 enrolled

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT03631576 2020-01-02

CD123/CLL1 CAR-T Cells for R/R AML (STPHI_0001)

20 enrolled

Leukemia, Myeloid, Acute

NCT02474290 2019-08-26

Sorafenib for Prophylaxis of Leukemia Relapse in Allo-HSCT Recipients With FLT3-ITD Positive AML

202 enrolled

Leukemia, Myeloid, Acute

NCT02472145 2019-03-19

An Efficacy and Safety Study of Decitabine (DACOGEN) Plus Talacotuzumab (JNJ-56022473; Anti CD123) Versus Decitabine (DACOGEN) Alone in Participants With Acute Myeloid Leukemia (AML) Ineligible for Intensive Chemotherapy

326 enrolled 20 charts

Leukemia, Myeloid, Acute

NCT03701217 2018-10-09

Eltrombopag Used in Thrombocytopenia After Comsolidation Therapy in AML

Classical hematologyOther hematologic neoplasm

220 enrolled

Thrombocytopenia, Leukemia, Myeloid, Acute

NCT03642236 2018-08-22

Combination of BTK Inhibitor Overcomes Drug-resistance in Refractory/Relapsed FLT3 Mutant AML

122 enrolled

Leukemia, Myeloid, Acute

NCT01588951 2018-08-14

Consolidation Therapy for Acute Myeloid Leukemia Guided by Leukemia Stem Cell Behavior

Phase 2/3 Terminated

10 enrolled 8 charts

Leukemia, Myeloid, Acute

NCT00151242 2017-09-20

Study on All-Trans Retinoic Acid, Induction and Consolidation Therapy, and Pegfilgrastim After Consolidation Therapy in Younger Patients With Newly Diagnosed Acute Myeloid Leukemia

920 enrolled

Leukemia, Myeloid, Acute

NCT03256071 2017-08-21

Low Dose Decitabine + Modified BUCY Conditioning Regimen for High Risk Acute Myeloid Leukemia Undergoing Allo-HSCT

90 enrolled

Leukemia, Myeloid, Acute

NCT00469729 2015-07-10

ExCell

101 enrolled

Hodgkin Disease, Leukemia, Lymphoid, Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00909168 2014-05-06

MYFLAI07

130 enrolled

Leukemia, Myeloid, Acute

NCT00454480 2013-08-26

Combination Chemotherapy With or Without Gemtuzumab Ozogamicin or Tipifarnib in Treating Patients With Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

Classical hematologyMyeloidOther hematologic neoplasm

2,000 enrolled

Congenital Abnormalities, Anemia, Refractory, with Excess of Blasts, Leukemia, Erythroblastic, Acute, Leukemia, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Basophilic, Acute, Leukemia, Eosinophilic, Acute, Leukemia, Myelomonocytic, Acute

NCT00004255 2013-07-10

Treatment of Bone Marrow to Prevent Graft-Versus-Host Disease in Patients With Acute or Chronic Leukemia Undergoing Bone Marrow Transplantation

Classical hematologyLymphoidMyeloidOther hematologic neoplasm

Anemia, Refractory, with Excess of Blasts, Graft vs Host Disease, Leukemia, Myelodysplastic Syndromes, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00398983 2013-03-04

Randomized Study of Decitabine in Maintenance Therapy of Acute Myeloid Leukemia (AML)

50 enrolled 6 charts

Leukemia, Myeloid, Acute

NCT00091234 2012-07-24

AML-19

279 enrolled

Congenital Abnormalities, Leukemia, Erythroblastic, Acute, Leukemia, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Basophilic, Acute, Leukemia, Eosinophilic, Acute, Leukemia, Myelomonocytic, Acute

NCT01015742 2012-06-04

Unrelated Double Umbilical Cord Blood Units Transplantation

10 enrolled

Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00111345 2012-05-23

Therapy-Optimization Trial for the Treatment of Acute Myeloid Leukemias (AML) in Children and Adolescents

550 enrolled

Leukemia, Leukemia, Myeloid, Leukemia, Myeloid, Acute

NCT00003187 2010-02-24

Bone Marrow Transplantation in Treating Patients With Leukemia, Myelodysplasia, or Lymphoblastic Lymphoma

Classical hematologyLymphoidMyeloidOther hematologic neoplasm

19 enrolled

Anemia, Refractory, Anemia, Refractory, with Excess of Blasts, Leukemia, Lymphoma, Myelodysplastic Syndromes, Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01015196 2009-11-18

AML2001

832 enrolled

Leukemia, Myeloid, Acute

NCT00300664 2006-10-13

A Randomized Trial of Human Growth Hormone (hGH) vs Placebo in Intensively Treated Haemato-Oncology Patients.