Clinical Trials

Leukemia, Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00566696 2020-04-14

Mismatched Family Member Donor Transplantation for Children and Young Adults With High Risk Hematological Malignancies

LymphoidMyeloidOther hematologic neoplasm

73 enrolled 16 charts

Hemoglobinuria, Hemoglobinuria, Paroxysmal, Hodgkin Disease, Leukemia, Lymphoma, Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Juvenile

NCT00562328 2020-04-08

Rituximab, Alemtuzumab, and GM-CSF As First-Line Therapy in Treating Patients With Early-Stage Chronic Lymphocytic Leukemia

33 enrolled 12 charts

LymphoidOther hematologic neoplasmPlasma cell

Leukemia, Leukemia, Lymphocytic, Chronic, B-Cell

NCT00048412 2020-01-18

Stem Cell Transplant for Patients With Blood Malignancy Using Donors and Less Toxic Chemotherapy With CAMPATH 1H

Phase 1/2 Completed

40 enrolled

Leukemia, Lymphoproliferative Disorders, Multiple Myeloma, Paraproteinemias

NCT00057005 2020-01-18

ADVL

Phase 1 Completed

6 enrolled

Other hematologic neoplasm

Leukemia

NCT00085449 2019-11-27

Alemtuzumab Plus Fludarabine and Melphalan With or Without Cyclosporine, Mycophenolate Mofetil, and Low-Dose Total-Body Irradiation Therapy Followed by Donor Peripheral Stem Cell Transplant in Treating Patients With Hematologic Cancer

Phase 1/2 Withdrawn

LymphoidMyeloidOther hematologic neoplasmPlasma cell

Congenital Abnormalities, Burkitt Lymphoma, Leukemia, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

NCT00997386 2019-09-09

ALBUM

Classical hematologyLymphoidMyeloidOther hematologic neoplasmPlasma cell

16 enrolled 7 charts

Anemia, Aplastic, Hemoglobinuria, Paroxysmal, Leukemia, Lymphoma, Multiple Myeloma, Myelodysplastic Syndromes, Hematologic Neoplasms, Primary Myelofibrosis

NCT01875237 2019-07-16

Donor Lymphocyte Infusion (DLI) of T-cells Genetically Modified With iCasp9 Suicide Gene

Phase 1/2 Terminated

3 enrolled 15 charts

LymphoidMyeloidOther hematologic neoplasmPlasma cell

Hodgkin Disease, Leukemia, Lymphoma, Multiple Myeloma, Myelodysplastic Syndromes, Neoplasms, Plasma Cell

NCT00801931 2019-03-27

Double Cord Blood Transplant for Patients With Malignant and Non-malignant Disorders

Phase 1/2 Terminated

1 enrolled 8 charts

CNSClassical hematologyLymphoidOther hematologic neoplasm

Anemia, Immunologic Deficiency Syndromes, Leukemia, Lymphoma, Neuroblastoma

NCT00943319 2019-02-04

Busulfan-fludarabine Conditioning and T-cell Depleted Allogeneic Stem Cell Transplantation for Patients With Advanced Hematologic Malignancies

Phase 1/2 Completed

50 enrolled 10 charts

LymphoidOther hematologic neoplasmPlasma cell

Leukemia, Lymphoma, Neoplasms, Plasma Cell

NCT01049854 2018-08-21

CD34+Selection for Partially Matched Family or Matched Unrelated Adult Donor Transplant

Classical hematologyLymphoidMyeloidOther hematologic neoplasm

20 enrolled

Bone Marrow Failure Disorders, Anemia, Sickle Cell, Immunologic Deficiency Syndromes, Leukemia, Lymphoma, Metabolism, Inborn Errors, Histiocytosis, beta-Thalassemia

NCT00301834 2017-09-28

Alemtuzumab, Fludarabine, and Busulfan Followed By Donor Stem Cell Transplant in Treating Young Patients With Hematologic Disorders

Classical hematologyMyeloidOther hematologic neoplasm

35 enrolled 11 charts

Congenital amegakaryocytic thrombocytopenia, Neutropenia, Severe Congenital, Autosomal Recessive 3, Leukemia, Myelodysplastic Syndromes, Leukemia, Myeloid, Chronic-Phase, Anemia, Diamond-Blackfan

NCT00416884 2017-09-27

Flu,Alemtuzumab,and TBI Followed By Donor Stem Cell Chronic Phase CML

Other hematologic neoplasm

1 enrolled 3 charts

Leukemia, Leukemia, Myeloid, Chronic-Phase

NCT01191749 2017-05-09

Alemtuzumab in Myelodysplastic Syndrome (MDS), Aplastic Anemia, and T-Cell Large Granular Lymphocytic Leukemia (T-GL)

Classical hematologyLymphoidMyeloidOther hematologic neoplasm

7 enrolled 6 charts

Anemia, Aplastic, Hematologic Diseases, Leukemia, Myelodysplastic Syndromes, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Large Granular Lymphocytic

NCT00698685 2017-03-31

Pentostatin and Alemtuzumab as a Preparative Regimen for Allogeneic Peripheral Blood Stem Cell Transplantation

GenitourinaryLymphoidMyeloidOther hematologic neoplasmPlasma cell

14 enrolled 7 charts

Carcinoma, Renal Cell, Hodgkin Disease, Leukemia, Lymphoma, Multiple Myeloma, Myelodysplastic Syndromes, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00104975 2016-12-15

Alemtuzumab and Combination Chemotherapy Followed By Donor Lymphocytes in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer

Phase 1 Completed

20 enrolled

Classical hematologyLymphoidMyeloidOther hematologic neoplasm

Pdgfra-Associated Chronic Eosinophilic Leukemia, Congenital Abnormalities, Anemia, Refractory, with Excess of Blasts, Blast Crisis, Burkitt Lymphoma, Leukemia, Lymphoma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Polycythemia Vera, Thrombocythemia, Essential, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Accelerated Phase, Leukemia, Neutrophilic, Chronic, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, Large-Cell, Immunoblastic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

NCT00578539 2016-04-22

REGALE

Phase NA Terminated

24 enrolled 7 charts

LymphoidMyeloidOther hematologic neoplasm

Hodgkin Disease, Leukemia, Lymphoma, Non-Hodgkin, Myeloproliferative Disorders

NCT00618969 2016-03-03

Peripheral Blood Stem Cell Transplantation (PBSCT)From Haploidentical Related Donors

Classical hematologyLymphoidOther hematologic neoplasmPlasma cell

2 enrolled

Anemia, Aplastic, Hemoglobinuria, Paroxysmal, Hodgkin Disease, Leukemia, Lymphoma, Non-Hodgkin, Multiple Myeloma, Hematologic Neoplasms, Neoplasms, Plasma Cell

NCT00587847 2015-10-15

Campath Maintenance in Chronic Lymphocytic Leukemia

Phase NA Terminated

12 enrolled 5 charts

Leukemia, Leukemia, Lymphocytic, Chronic, B-Cell

NCT00771602 2015-06-23

Alemtuzumab + Rituximab Consolidation in CLL

1 enrolled 2 charts

Leukemia, Leukemia, Lymphocytic, Chronic, B-Cell

NCT00230282 2014-10-06

Phase 2 Fludarabine, Cytoxan and FCCAM <Alemtuzumab> in Untreated B-Cell Chronic Lymphocytic Leukemia

25 enrolled 7 charts

Leukemia, Leukemia, B-Cell, Leukemia, Lymphocytic, Chronic, B-Cell

NCT00669318 2014-07-01

Pentostatin, Alemtuzumab, and Rituximab in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

41 enrolled 9 charts

Other hematologic neoplasm

Leukemia, Lymphoma, Leukemia, Lymphocytic, Chronic, B-Cell

NCT00943592 2014-02-27

Clofarabine-Melphalan-Alemtuzumab Conditioning in Patients With Advanced Hematologic Malignancies

Phase 1/2 Completed

82 enrolled 12 charts

Leukemia, Preleukemia

NCT00021151 2014-01-09

Compassionate Use of Campath-1H in Treating Patients With Refractory Prolymphocytic Leukemia or Chronic Lymphocytic Leukemia

Phase NA Completed

2 enrolled

Leukemia, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Prolymphocytic

NCT00818961 2013-12-18

Donor Stem Cell Transplant in Treating Patients With High-Risk Hematologic Cancer

LymphoidMyeloidOther hematologic neoplasm

36 enrolled 16 charts

Congenital Abnormalities, Blast Crisis, Hodgkin Disease, Immunoblastic Lymphadenopathy, Leukemia, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Myelodysplastic Syndromes, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Prolymphocytic, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myelomonocytic, Chronic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Myelodysplastic-Myeloproliferative Diseases

NCT00564512 2013-07-25

Fludarabine, Cyclophosphamide, and Rituximab or Alemtuzumab in Treating CLL2007 CLL 2007 FMP

Phase 3 Completed

178 enrolled

Leukemia, Leukemia, Lymphocytic, Chronic, B-Cell

NCT00525603 2013-03-04

CFAR Study in Patients With Chronic Lymphocytic Leukemia

60 enrolled 5 charts

Leukemia, Leukemia, Lymphocytic, Chronic, B-Cell

NCT00069992 2012-10-10

MPDMDSBMT

MyeloidOther hematologic neoplasm

7 enrolled

Congenital Abnormalities, Leukemia, Myelodysplastic Syndromes, Myeloproliferative Disorders, Polycythemia Vera, Thrombocythemia, Essential, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Primary Myelofibrosis

NCT00453193 2012-08-07

Alemtuzumab and Pentostatin In T-cell Neoplasms

26 enrolled 5 charts

Leukemia, Lymphoma

NCT00436904 2011-12-01

Alemtuzumab and Rituximab in Treating Patients With High-Risk, Early-Stage Chronic Lymphocytic Leukemia

30 enrolled 10 charts

Leukemia, Leukemia, Lymphocytic, Chronic, B-Cell

NCT00038844 2011-11-02

Safety and Efficacy of Campath in Nonmyeloablative Transplantation

Phase NA Completed

65 enrolled

Leukemia, Lymphoma

NCT00109993 2010-06-11

Campath-1H + FK506 and Methylprednisolone for GVHD

BreastCNSDermatologicGenitourinaryGynecologicLymphoidMyeloidOther hematologic neoplasmPlasma cell

34 enrolled

Testicular Germ Cell Tumor, Pdgfra-Associated Chronic Eosinophilic Leukemia, Congenital Abnormalities, Carcinoma, Ovarian Epithelial, Blast Crisis, Breast Neoplasms, Burkitt Lymphoma, Graft vs Host Disease, Hodgkin Disease, Leukemia, Leukemia, Hairy Cell, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Multiple Myeloma, Mycosis Fungoides, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neuroblastoma, Ovarian Neoplasms, Sezary Syndrome, Testicular Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Neutrophilic, Chronic, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Gestational Trophoblastic Disease, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

NCT00410657 2010-05-14

Alemtuzumab and Glucocorticoids in Treating Newly Diagnosed Acute Graft-Versus-Host Disease in Patients Who Have Undergone a Donor Stem Cell Transplant