Clinical Trials Browser

Phase 2 × Interventional × Leukoplakia, Oral × Clear all

NCT02581137 2026-03-18

Metformin Hydrochloride in Preventing Oral Cancer in Patients With an Oral Premalignant Lesion

Phase 2 Active not recruiting

26 enrolled 10 charts

Erythroplasia, Hyperplasia, Leukoplakia, Oral, Mouth Neoplasms

NCT07387900 2026-02-06

Evaluation of the Chemo-preventive Effect of Combined Topical and Systemic Metformin on Oral Leukoplakia

Phase 2 Recruiting

Leukoplakia, Oral

NCT05727761 2025-12-24

Pioglitazone-Metformin Combination Treatment for High Risk Oral Preneoplasia

Phase 2 Recruiting

Leukoplakia, Oral

NCT05237960 2025-09-29

Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia

Phase 2 Active not recruiting

Erythroplasia, Leukoplakia, Oral

NCT03692325 2024-10-01

Safety and Efficacy of Nivolumab in Treating Oral Proliferative Verrucous Leukoplakia

Phase 2 Completed

33 enrolled 15 charts

Leukoplakia, Oral

NCT00099021 2022-02-11

Pioglitazone Hydrochloride in Preventing Head and Neck Cancer in Patients With Oral Leukoplakia

Phase 2 Completed

21 enrolled 6 charts

Head and Neck Neoplasms, Leukoplakia, Oral

NCT00951379 2016-04-06

Pioglitazone for Oral Premalignant Lesions

Phase 2 Terminated

52 enrolled 23 charts

Leukoplakia, Oral

NCT00330382 2014-12-19

Bowman-Birk Inhibitor Concentrate in Preventing Cancer in Patients With Oral Leukoplakia

Phase 2 Completed

325 enrolled 15 charts

Leukoplakia, Oral, Mouth Neoplasms, Oropharyngeal Neoplasms, Tongue Neoplasms

NCT00101335 2013-07-11

Celecoxib in Preventing Head and Neck Cancer in Patients With Oral Leukoplakia

Phase 2 Completed

Head & NeckOther neoplasm

Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Leukoplakia, Oral, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Precancerous Conditions, Tongue Neoplasms

NCT00369174 2013-02-13

Rosiglitazone Maleate in Treating Patients With Oral Leukoplakia

Phase 2 Completed

Leukoplakia, Oral

NCT00176566 2009-12-11

A Phase II Trial to Assess the Effects of Green Tea in Oral Leukoplakia

Phase 2 Terminated

Leukoplakia, Oral