Clinical Trials

GastrointestinalGenitourinarySarcoma

Leiomyosarcoma, Liposarcoma, Sarcoma

NCT07262970 2025-12-04

Intermediate-Size Cohort EAP for Ersodetug in Patients With Inadequately Controlled Hypoglycemia Related to a Tumor

Available

EndocrineNETSarcoma

Fibrosarcoma, Hyperinsulinism, Hypoglycemia, Insulinoma, Adenoma, Islet Cell, Liposarcoma, Neoplasms, Neuroectodermal Tumors, Primitive, Neuroendocrine Tumors

NCT06198296 2025-11-03

Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells

Phase 1 Recruiting

21 enrolled

Carcinoma, Hepatocellular, Liposarcoma, Wilms Tumor, Rhabdomyosarcoma, Hepatoblastoma, Endodermal Sinus Tumor, Rhabdoid Tumor

NCT05886634 2025-10-20

A Study of Etrumadenant and Zimberelimab in People With Dedifferentiated Liposarcoma

16 enrolled

Liposarcoma, Sarcoma

NCT04438824 2025-10-14

Palbociclib and INCMGA00012 in People With Advanced Liposarcoma

42 enrolled

Liposarcoma

NCT04668300 2025-10-09

DOSa

75 enrolled

Phase 1 Active not recruiting

Hemangiosarcoma, Liposarcoma, Osteosarcoma

NCT03361436 2025-09-16

Eribulin and Radiation Therapy in Treating Patients With Retroperitoneal Liposarcoma That Can Be Removed by Surgery

15 enrolled

Liposarcoma

NCT01841047 2025-09-03

TOMOREP

Phase NA Completed

48 enrolled 15 charts

Liposarcoma

NCT03899805 2025-08-28

A Phase II Study of Eribulin and Pembrolizumab in Soft Tissue Sarcomas

57 enrolled 14 charts

Leiomyosarcoma, Liposarcoma, Sarcoma, Histiocytoma, Malignant Fibrous

NCT04242238 2025-08-28

Study of DCC-3014 in Combination With Avelumab in Patients With Advanced or Metastatic Sarcomas

Phase 1 Completed

32 enrolled

Leiomyosarcoma, Liposarcoma, Sarcoma, Dermatofibrosarcoma, Histiocytoma, Malignant Fibrous

NCT02846987 2025-06-05

Study of Abemaciclib in Dedifferentiated Liposarcoma

33 enrolled

GastrointestinalGenitourinarySarcoma

Liposarcoma, Sarcoma

NCT04715191 2025-05-02

Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors

Phase 1 Recruiting

24 enrolled

Liposarcoma, Liver Neoplasms, Wilms Tumor, Rhabdomyosarcoma, Endodermal Sinus Tumor, Rhabdoid Tumor

NCT03719430 2025-04-29

APX005M and Doxorubicin in Advanced Sarcoma

27 enrolled

Leiomyosarcoma, Liposarcoma, Sarcoma, Sarcoma, Synovial, Neurofibrosarcoma

NCT03114527 2025-04-04

Phase II Trial of Ribociclib and Everolimus in Advanced Dedifferentiated Liposarcoma (DDL) and Leiomyosarcoma (LMS)

48 enrolled

Phase EARLY_PHASE1 Terminated

Leiomyosarcoma, Liposarcoma, Sarcoma

NCT04213794 2025-02-20

TOASTIT

2 enrolled

GastrointestinalGynecologicOther solid neoplasmSarcomaThoracic

Mesothelioma, Malignant, Colonic Neoplasms, Fallopian Tube Neoplasms, Liposarcoma, Ovarian Neoplasms, Pelvic Neoplasms, Rectal Neoplasms, Rhabdomyosarcoma, Sarcoma, Stomach Neoplasms, Desmoplastic Small Round Cell Tumor

NCT04224064 2025-02-12

ESPACE

Phase NA Recruiting

158 enrolled

Liposarcoma, Neoplasms

NCT02249949 2025-01-27

Efatutazone Dihydrochloride in Treating Patients With Previously Treated Myxoid Liposarcoma That Cannot Be Removed by Surgery

15 enrolled 12 charts

Phase 2 Not yet recruiting

Liposarcoma

NCT06694324 2024-11-19

First-line Treatment of Advanced/unresectable DDLPS

49 enrolled

Liposarcoma, Sarcoma

NCT02978859 2024-07-18

Sitravatinib in Advanced Liposarcoma and Other Soft Tissue Sarcomas

29 enrolled 11 charts

Liposarcoma, Sarcoma

NCT02048371 2023-11-07

SARC024: A Blanket Protocol to Study Oral Regorafenib in Patients With Selected Sarcoma Subtypes

131 enrolled 22 charts

Liposarcoma, Rhabdomyosarcoma, Osteosarcoma, Chondrosarcoma, Mesenchymal

NCT02584309 2023-11-07

Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma

73 enrolled 11 charts

Fibrosarcoma, Hemangiosarcoma, Leiomyosarcoma, Liposarcoma, Sarcoma, Sarcoma, Synovial, Dermatofibrosarcoma, Neurofibrosarcoma, Histiocytoma, Malignant Fibrous

NCT03009201 2023-08-16

Ribociclib and Doxorubicin in Treating Patients With Metastatic or Advanced Soft Tissue Sarcomas That Cannot Be Removed by Surgery

Phase 1 Completed

16 enrolled

Fibrosarcoma, Hemangiosarcoma, Liposarcoma, Sarcoma, Disorders of Sex Development, Sarcoma, Synovial, Dermatofibrosarcoma, Neurofibrosarcoma, Histiocytoma, Malignant Fibrous

NCT00004180 2023-06-26

Rosiglitazone in Treating Patients With Liposarcoma

32 enrolled

Liposarcoma, Sarcoma

NCT02275286 2023-05-31

TRASTS

Phase 1/2 Recruiting

199 enrolled

Leiomyosarcoma, Liposarcoma, Sarcoma, Liposarcoma, Myxoid

NCT00346125 2022-12-15

PET CT as Predictor of Response in Preoperative Chemotherapy for Soft Tissue Sarcoma

Phase NA Completed

70 enrolled

Fibrosarcoma, Leiomyosarcoma, Liposarcoma, Sarcoma, Sarcoma, Synovial, Neurofibrosarcoma, Histiocytoma, Malignant Fibrous

NCT03959033 2022-08-31

Patient Reported Outcome Measures (PROMs) With Trabectedin

Terminated

7 enrolled

Leiomyosarcoma, Liposarcoma, Sarcoma

NCT02357810 2022-06-07

Pazopanib Hydrochloride and Topotecan Hydrochloride in Treating Patients With Metastatic Soft Tissue and Bone Sarcomas

178 enrolled 16 charts

Liposarcoma, Sarcoma, Osteosarcoma

NCT03074318 2022-04-29

Avelumab and Trabectedin in Treating Patients With Liposarcoma or Leiomyosarcoma That is Metastatic or Cannot Be Removed by Surgery

Phase 1/2 Terminated

35 enrolled 21 charts

Leiomyosarcoma, Liposarcoma

NCT04512495 2021-12-10

SAMHY SARCOME

Phase NA Completed

60 enrolled

Leiomyosarcoma, Liposarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Liposarcoma, Myxoid

NCT05116800 2021-12-07

Phase 2 Study of 9-ING-41 With Chemotherapy in Sarcoma

Phase 2 Withdrawn

Bone Neoplasms, Hemangiosarcoma, Leiomyosarcoma, Liposarcoma, Rhabdomyosarcoma, Sarcoma, Osteosarcoma, Sarcoma, Synovial, Dermatofibrosarcoma, Histiocytoma, Malignant Fibrous

NCT01532687 2021-09-27

Gemcitabine With or Without Pazopanib in Treating Patients With Refractory Soft Tissue Sarcoma

54 enrolled 12 charts

Chondrosarcoma, Extraskeletal Myxoid, Fibrosarcoma, Hemangiosarcoma, Leiomyosarcoma, Liposarcoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Synovial, Sarcoma, Alveolar Soft Part, Neurofibrosarcoma, Hemangioendothelioma, Epithelioid, Histiocytoma, Malignant Fibrous, Desmoplastic Small Round Cell Tumor

NCT04906876 2021-07-28

A Phase 2 Study of 9-ING-41Combined With Chemotherapy in Adolescents and Adults With Advanced Sarcomas

Phase 2 Withdrawn

Bone Neoplasms, Hemangiosarcoma, Leiomyosarcoma, Liposarcoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Synovial, Dermatofibrosarcoma, Histiocytoma, Malignant Fibrous

NCT00423618 2021-03-18

VORTEX

Phase 3 Completed

216 enrolled

Malignant mesenchymal tumor, Hemangiopericytoma, Malignant, Chondrosarcoma, Extraskeletal Myxoid, Fibrosarcoma, Hemangiosarcoma, Leiomyosarcoma, Liposarcoma, Sarcoma, Sarcoma, Synovial, Sarcoma, Alveolar Soft Part, Neurofibrosarcoma, Histiocytoma, Malignant Fibrous

NCT01876043 2021-01-25

APLIPO

Phase 2 Terminated

24 enrolled 10 charts

Liposarcoma, Neoplasm Metastasis, Recurrence

NCT03651375 2021-01-22

UN-RESARC

Phase 2 Unknown

46 enrolled

Fibrosarcoma, Leiomyosarcoma, Liposarcoma, Lymphangiosarcoma, Myosarcoma, Sarcoma, Sarcoma, Synovial, Liposarcoma, Myxoid, Dermatofibrosarcoma, Neurofibrosarcoma, Histiocytoma, Malignant Fibrous, Histiocytic Sarcoma

NCT03880123 2020-11-27

Selinexor in Combination With Ixazomib for the Treatment of Advanced Sarcoma

Phase 1 Withdrawn

Liposarcoma, Sarcoma, Sarcoma, Ewing, Sarcoma, Alveolar Soft Part, Neurofibrosarcoma

NCT03303885 2020-10-19

FILIPO

Completed

421 enrolled

Liposarcoma

NCT01883518 2019-11-20

ADCVCTAST

Phase 1/2 Unknown

48 enrolled

Chondrosarcoma, Fibrosarcoma, Leiomyosarcoma, Liposarcoma, Myosarcoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Synovial, Neoplasms, Connective and Soft Tissue, Sarcoma, Alveolar Soft Part, Neurofibrosarcoma, Histiocytoma, Histiocytoma, Malignant Fibrous

NCT00949325 2019-03-11

Safety and Efficacy Study of Torisel and Liposomal Doxorubicin for Patients With Recurrent Sarcoma

Phase 1/2 Completed

24 enrolled 14 charts