Clinical Trials

GastrointestinalGenitourinary

36 enrolled

Urinary Bladder Neoplasms, Gastrointestinal Neoplasms, Liver Neoplasms

NCT06600321 2026-02-17

A Study to Evaluate ALN-BCAT in Patients With Hepatocellular Carcinoma

158 enrolled

Carcinoma, Hepatocellular, Liver Diseases, Liver Neoplasms

NCT06229080 2026-02-12

SEGWAY

Phase NA Completed

20 enrolled

Liver Neoplasms, Neoplasm Metastasis

NCT06440005 2026-02-11

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

BreastGastrointestinalGenitourinarySarcoma

80 enrolled

Breast Neoplasms, Hemangiosarcoma, Liver Neoplasms, Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms

NCT06679985 2026-02-05

A Trial of Casdozokitug in Combination With Toripalimab Plus Bevacizumab in Participants With Unresectable and/or Locally Advanced or Metastatic Hepatocellular Carcinoma

Phase 2 Recruiting

72 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms

NCT07390838 2026-02-05

A Study of SH009 Injection in Patients With Advanced Solid Tumors.

BreastGastrointestinalThoracic

150 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Liver Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Stomach Neoplasms

NCT04736121 2026-02-03

DOORwaY90

Phase NA Active not recruiting

100 enrolled

Liver Neoplasms

NCT05150691 2026-01-28

A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors

BreastGastrointestinalGynecologicThoracic

796 enrolled

Bile Duct Neoplasms, Biliary Tract Neoplasms, Breast Neoplasms, Carcinoma, Carcinoma, Non-Small-Cell Lung, Gastrointestinal Neoplasms, Liver Neoplasms, Neoplasm Metastasis, Neoplasms, Recurrence, Stomach Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT07362264 2026-01-23

A Study of SH006 Injection Combination Therapy in Patients With Advanced Solid Tumors

Phase 1 Active not recruiting

50 enrolled

BreastGastrointestinalGenitourinaryHead & NeckOther solid neoplasmThoracic

Liver Neoplasms

NCT05070247 2026-01-22

A Study of TAK-500 With or Without Pembrolizumab in Adults With Select Locally Advanced or Metastatic Solid Tumors

Phase 1/2 Terminated

61 enrolled 29 charts

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Kidney Neoplasms, Liver Neoplasms, Mesothelioma, Nasopharyngeal Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms

NCT07317505 2026-01-21

A Phase 1 Study of JMT108 in Participants With Advanced Solid Tumors

DermatologicGastrointestinal

270 enrolled

Liver Neoplasms, Melanoma, Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT07356531 2026-01-21

Clinical Trial Evaluating the Safety and Efficacy of Tumor Thermosensitive Embolic Agent in Transcatheter Arterial Chemoembolization for Primary Liver Cancer

Phase NA Recruiting

216 enrolled

Phase 2 Active not recruiting

Liver Neoplasms

NCT06040099 2026-01-20

EMERALD-Y90

56 enrolled

Phase 3 Active not recruiting

Carcinoma, Hepatocellular, Liver Neoplasms

NCT03778957 2026-01-16

EMERALD-1

724 enrolled

Phase 1/2 Not yet recruiting

Carcinoma, Hepatocellular, Liver Neoplasms

NCT07341737 2026-01-15

SL-28 for Advanced Solid Tumours

60 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Adenocarcinoma of Lung, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Head and Neck Neoplasms, Intestinal Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT04573881 2026-01-12

#HOPE4LIVER

Phase NA Active not recruiting

24 enrolled 12 charts

Carcinoma, Hepatocellular, Liver Neoplasms

NCT06478693 2025-12-18

A Study of MT-303 in Adults With Advanced or Metastatic GPC3-Expressing Cancers, Including HCC

70 enrolled

Simpson-Golabi-Behmel syndrome, Carcinoma, Hepatocellular, Liver Neoplasms

NCT07227012 2025-12-18

A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.

138 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms

NCT04864054 2025-12-05

ARYA-3

20 enrolled

Phase 1/2 Not yet recruiting

Carcinoma, Hepatocellular, Liver Neoplasms

NCT07260058 2025-12-02

Immune Cell Therapy for Advanced Solid Tumors

48 enrolled

BreastGastrointestinalThoracic

Breast Neoplasms, Liver Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Colorectal Neoplasms

NCT03383458 2025-11-21

CheckMate 9DX

Phase 3 Active not recruiting

545 enrolled

Phase NA Not yet recruiting

Carcinoma, Hepatocellular, Liver Neoplasms

NCT07226869 2025-11-12

MWA Sim

100 enrolled

GastrointestinalGenitourinaryThoracic

Carcinoma, Hepatocellular, Liver Neoplasms

NCT04374877 2025-11-10

Study of CHS-388 (Formerly Known as SRF388) in Patients With Advanced Solid Tumors

Phase 1 Completed

145 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Hepatocellular, Kidney Neoplasms, Liver Neoplasms, Neoplasms

NCT06858813 2025-11-10

A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)

232 enrolled

Liver Neoplasms

NCT05033522 2025-10-23

ALIVE

Phase 2/3 Suspended

150 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms

NCT00422877 2025-10-16

Taxoprexin® Treatment for Advanced Primary Cancers of the Liver, Gallbladder or Biliary Tract

Phase 2 Terminated

13 enrolled

DermatologicGastrointestinalGenitourinaryGynecologic

Liver Neoplasms

NCT05293496 2025-10-14

A Study of MGC018 in Combination With MGD019 in Participants With Advanced Solid Tumors

Phase 1 Completed

31 enrolled

Carcinoma, Ovarian Epithelial, Carcinoma, Renal Cell, Liver Neoplasms, Melanoma, Carcinoma, Pancreatic Ductal, Prostatic Neoplasms, Castration-Resistant

NCT03993873 2025-10-01

SHIELD-1

Phase 1 Active not recruiting

95 enrolled

GastrointestinalThoracic

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Liver Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Stomach Neoplasms

NCT06362369 2025-09-17

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

DermatologicGastrointestinalGenitourinaryOther solid neoplasmThoracic

126 enrolled

Turcot syndrome, Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Hepatocellular, Kidney Neoplasms, Liver Neoplasms, Melanoma, Neoplasm Metastasis, Skin Neoplasms, Colorectal Neoplasms

NCT05582018 2025-09-15

PANORAMA

Phase NA Terminated

4 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms

NCT04502082 2025-09-08

Study of ET140203 T Cells in Adults With Advanced Hepatocellular Carcinoma (ARYA-1)

Phase 1 Terminated

8 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms

NCT05411133 2025-09-04

Treatment of Cabotamig (ARB202) in Advanced Gastrointestinal Cancer Patients

68 enrolled

Phase 3 Not yet recruiting

Adenocarcinoma Of Esophagus, Gastrointestinal Neoplasms, Liver Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Cholangiocarcinoma

NCT06680258 2025-09-03

A Study of TPST-1120 With Atezolizumab Plus Bevacizumab in Patients With Unresectable or Metastatic HCC Not Previously Treated With Systemic Therapy

740 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms, Neoplasm Metastasis

NCT06873659 2025-09-03

SON-DP in Participants With Relapsed/Refractory Intolerant to Standard of Care Therapies for Advanced/Metastatic Solid Tumors

96 enrolled

Phase 1 Active not recruiting

Liver Neoplasms, Stomach Neoplasms

NCT03132792 2025-08-15

AFPᶜ³³²T in Advanced HCC

45 enrolled

BreastGastrointestinalGenitourinaryGynecologicThoracic

Liver Neoplasms, Neoplasm Metastasis

NCT03199586 2025-07-20

Clinical Trial of Metastasis Inhibitor NP-G2-044 in Patients With Advanced or Metastatic Treatment-Refractory Solid Tumor Malignancies

Phase 1 Completed

23 enrolled

Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Liver Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms

NCT06239194 2025-06-22

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

115 enrolled

Biliary Tract Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms, Thyroid Neoplasms, Endometrial Neoplasms

NCT04696055 2025-05-13

Regorafenib Plus Pembrolizumab in Patients With Advanced or Spreading Liver Cancer Who Have Been Previously Treated With PD-1/PD-L1 Immune Checkpoint Inhibitors

Phase 2 Completed

95 enrolled 14 charts

Carcinoma, Hepatocellular, Liver Neoplasms

NCT05201404 2025-04-29

LIVERATION

Phase 3 Recruiting

471 enrolled