Clinical Trials

18 enrolled

Phase 1 Not yet recruiting

Fibrolamellar hepatocellular carcinoma, Carcinoma, Hepatocellular, Liver Neoplasms

NCT07430202 2026-02-24

A DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Glutamine Antagonist DRP-104, Nivolumab, and Ipilimumab in Patients With Advanced Stage Fibrolamellar Carcinoma (FLC)

27 enrolled

Fibrolamellar hepatocellular carcinoma, Carcinoma, Liver Neoplasms

NCT04258813 2026-02-20

ONE TEAM

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

313 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Cardiovascular Diseases, Colonic Neoplasms, Diabetes Mellitus, Esophageal Neoplasms, Head and Neck Neoplasms, Hypercholesterolemia, Hypertension, Liver Neoplasms, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Endometrial Neoplasms

NCT04907643 2026-02-20

Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes

EndocrineGastrointestinalNET

360 enrolled

Cancer Pain, Anus Neoplasms, Appendiceal Neoplasms, Bile Duct Neoplasms, Biliary Tract Neoplasms, Carcinoid Tumor, Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Liver Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Rectal Neoplasms, Recurrence, Stomach Neoplasms, Neuroendocrine Tumors, Visceral Pain

NCT06958224 2026-02-20

ESCAT

360 enrolled

BreastGastrointestinal

Breast Neoplasms, Liver Neoplasms

NCT06608940 2026-02-19

BC3402 w/ Tremelimumab + Durvalumab (STRIDE) in Hepatocellular Carcinoma

Phase 1/2 Withdrawn

Liver Neoplasms

NCT07407257 2026-02-18

SBRT for Liver Tumors, Liver Metastases, and Pancreatic Tumors

65 enrolled

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicLymphoidOther hematologic neoplasmPlasma cellThoracic

Carcinoma, Hepatocellular, Liver Neoplasms, Pancreatic Neoplasms

NCT07410494 2026-02-18

SELECT-CAR-NK

Phase 1/2 Recruiting

85 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Glioblastoma, Carcinoma, Hepatocellular, Liver Neoplasms, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Melanoma, Multiple Myeloma, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Leukemia, Myeloid, Acute

NCT07410676 2026-02-18

EBNK-ST-001

Phase 1/2 Recruiting

83 enrolled

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicOther hematologic neoplasmSarcomaThoracic

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Bronchogenic, Disease, Esophageal Neoplasms, Glioblastoma, Kidney Neoplasms, Leukemia, Liver Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms

NCT07148050 2026-02-17

IMPACT

Phase 1 Recruiting

21 enrolled

GastrointestinalGenitourinarySarcoma

Carcinoma, Hepatocellular, Liposarcoma, Liver Neoplasms, Wilms Tumor, Rhabdomyosarcoma, Hepatoblastoma, Endodermal Sinus Tumor, Rhabdoid Tumor

NCT07297615 2026-02-17

3D Liver Volumetry

25 enrolled

Liver Neoplasms

NCT04288323 2026-02-12

Gadolinium Contrast-enhanced Abbreviated MRI (AMRI) vs. Standard Ultrasound for Hepatocellular Carcinoma (HCC) Surveillance in Patients With Cirrhosis

Phase 4 Completed

79 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms

NCT07223307 2026-02-09

REGULUS: MRI-guided Adaptive SABR for Liver Cancers

62 enrolled

Liver Neoplasms, Cholangiocarcinoma

NCT07337330 2026-02-02

Ultrasound Guided External Oblique Intercostal Plane Block Versus Erector Spinae Block for Post Hepatectomy Pain

52 enrolled

Cancer Pain, Liver Neoplasms

NCT07110233 2026-01-23

Yttrium-90 Radiation Segmentectomy for Hepatocellular Carcinoma

64 enrolled

Phase 1 Active not recruiting

Carcinoma, Hepatocellular, Liver Neoplasms

NCT04377932 2026-01-21

Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors

14 enrolled 12 charts

GastrointestinalGenitourinarySarcoma

Liposarcoma, Liver Neoplasms, Wilms Tumor, Rhabdomyosarcoma, Endodermal Sinus Tumor, Rhabdoid Tumor

NCT05155189 2026-01-21

A Study to Evaluate Safety and Efficacy of Armored CAR-T Cell Injection C-CAR031 in Advanced Hepatocellular Carcinoma

Phase 1 Recruiting

72 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms

NCT05153785 2026-01-15

Perioperative Intravenous Lidocaine in Liver Surgery

Phase 2/3 Completed

124 enrolled

Phase 2 Not yet recruiting

Liver Neoplasms, Pain, Postoperative

NCT06855225 2026-01-14

A Phase II Study of Single Tremelimumab With Regular Interval Durvalumab Plus Gemcitabine and Cisplatin in Locally Advanced Unresectable/Metastatic Combined Hepatocellular-cholangiocarcinoma

29 enrolled

Liver Neoplasms

NCT03611309 2026-01-08

PERIOP-PC

379 enrolled 15 charts

Esophageal Neoplasms, Gastrointestinal Neoplasms, Liver Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms

NCT01494324 2026-01-02

Examinations of Tissue From Ablated Malignant Liver Metastases as Predictors of Outcome

150 enrolled

Liver Neoplasms

NCT06715839 2025-12-31

Target-specific immunoPET Imaging of Digestive System Carcinoma

400 enrolled

Phase 2 Not yet recruiting

Simpson-Golabi-Behmel syndrome, Appendiceal Neoplasms, Bile Duct Neoplasms, Colonic Neoplasms, Digestive System Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Liver Neoplasms, Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT07312292 2025-12-31

RADIANT

15 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms, Neoplasm Metastasis

NCT05532319 2025-12-30

FRONT-1

Phase 2 Completed

64 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms

NCT05727787 2025-12-24

vGRID SBRT

18 enrolled

Liver Neoplasms

NCT00243633 2025-12-23

Characterization of Focal Liver Lesions by Real-time Contrast-enhanced Ultrasound Imaging (CEUS)

878 enrolled

Phase EARLY_PHASE1 Recruiting

Fibrosis, Liver Cirrhosis, Liver Neoplasms

NCT07295262 2025-12-19

NIR-II Fluorescence-Guided Hepatectomy Using ICG-Cisplatin Nanoprobes for HCC

30 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms

NCT04618692 2025-12-18

Biliary Anastomosis Using Surgical Loupe Versus Microscope in Living Donor Liver Transplantation

52 enrolled

Phase 1 Active not recruiting

Liver Diseases, Liver Neoplasms, Liver Failure

NCT04658147 2025-12-18

Feasibility and Efficacy of Perioperative Nivolumab With or Without Relatlimab for Patients With Potentially Resectable Hepatocellular Carcinoma (HCC)

31 enrolled

Phase 1 Active not recruiting

Carcinoma, Hepatocellular, Liver Neoplasms

NCT02869217 2025-12-03

Study of TBI-1301 (NY-ESO-1 Specific TCR Gene Transduced Autologous T Lymphocytes) in Patients With Solid Tumors

22 enrolled

DermatologicGastrointestinalGenitourinaryGynecologicSarcomaThoracic

Urinary Bladder Neoplasms, Esophageal Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Ovarian Neoplasms, Sarcoma, Synovial

NCT06084234 2025-11-26

TRACER

Phase 4 Recruiting

5,500 enrolled

Hepatitis B, Carcinoma, Hepatocellular, Liver Cirrhosis, Liver Neoplasms

NCT07246668 2025-11-24

A Phase II Single-Arm Clinical Study to Evaluate the Efficacy and Safety of Carbon Ion Radiotherapy With Atezolizumab and Bevacizumab Combination Therapy in Patients With Advanced Hepatocellular Carcinoma

52 enrolled

Carcinoma, Carcinoma, Hepatocellular, Liver Neoplasms

NCT04933435 2025-11-19

Interventional Radiology Liver Directed Therapies and Hypofractionated Image-Guided Radiation Therapy in Veteran and Non-Veteran, Non-surgical Hepatocellular Carcinoma Patients

78 enrolled

Liver Neoplasms

NCT00183885 2025-10-30

A Phase II Study of Intra-arterial Chemotherapy With Cisplatin and Mitomycin-C in Patients With Hepatocellular Carcinoma

Phase 2 Completed

76 enrolled 10 charts

Carcinoma, Hepatocellular, Liver Neoplasms

NCT02881554 2025-10-29

Sulfur Colloid SPECT/CT in Measuring Liver Function in Patients With Primary or Metastatic Liver Cancer Undergoing Radiation Therapy or Surgery

Phase NA Terminated

41 enrolled 14 charts

Carcinoma, Hepatocellular, Liver Neoplasms, Thrombosis, Cholangiocarcinoma

NCT06171945 2025-10-27

AYAConnect

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOtherOther hematologic neoplasmSarcoma

63 enrolled

Psychological Well-Being, Urinary Bladder Neoplasms, Bone Neoplasms, Brain Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Colonic Neoplasms, Head and Neck Neoplasms, Hodgkin Disease, Kidney Neoplasms, Leukemia, Liver Neoplasms, Lymphoma, Non-Hodgkin, Melanoma, Motor Activity, Mouth Neoplasms, Neoplasms, Obesity, Pancreatic Neoplasms, Pharyngeal Neoplasms, Rectal Neoplasms, Sarcoma, Testicular Neoplasms, Thyroid Neoplasms, Weight Loss, Endometrial Neoplasms, Overweight

NCT03879161 2025-10-16

A Percutaneous Ultrasound Device With Needle Guide for Vascular Access

Phase NA Withdrawn

Liver Neoplasms

NCT07214363 2025-10-09

The Safety and Efficacy of Irreversible Electroporation for the Treatment of Perivascular Liver Cancers

20 enrolled

Liver Neoplasms

NCT05128032 2025-10-08

PEDIR

20 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms, Colorectal Neoplasms

NCT07145801 2025-10-07

TARE

30 enrolled

Carcinoma, Carcinoma, Hepatocellular, Liver Neoplasms

NCT07207343 2025-10-03

Symptomatic Abdominal Tumors Are Unsuitable for Surgical Resection, High-intensity Focused Ultrasound (HIFU) Treatment Will be Applied to the Tumors. Postoperatively, Continuous Evaluation and Analysis of the Ablation Effect Will be Performed Using CT or MRI Imaging.

38 enrolled