Clinical Trials

Phase 3 Active not recruiting

Lung Neoplasms

NCT03811002 2026-03-18

Testing the Addition of a New Immunotherapy Drug, Atezolizumab (MPDL3280A), to the Usual Chemoradiation (CRT) Therapy Treatment for Limited Stage Small Cell Lung Cancer (LS-SCLC)

544 enrolled 29 charts

BreastCNSDermatologicOther hematologic neoplasmThoracic

Lung Neoplasms

NCT04789668 2026-03-18

Bintrafusp Alfa and Pimasertib for the Treatment of Patients With Brain Metastases

Phase 1/2 Terminated

8 enrolled 13 charts

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Hematologic Neoplasms, Triple Negative Breast Neoplasms

NCT04902040 2026-03-18

Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted Antibodies

Phase 1/2 Terminated

19 enrolled 11 charts

GenitourinaryThoracic

Urinary Bladder Neoplasms, Carcinoma, Renal Cell, Lung Neoplasms

NCT02971501 2026-03-17

Osimertinib With or Without Bevacizumab in Treating Patients With EGFR Positive Non-small Cell Lung Cancer and Brain Metastases

Phase 2 Active not recruiting

7 enrolled 9 charts

CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06052449 2026-03-11

Assessing Social Determinants of Health to Increase Cancer Screening

101 enrolled 22 charts

Lung Neoplasms

NCT04222972 2026-03-05

AcceleRET-Lung

Phase 3 Terminated

223 enrolled 18 charts

Head & NeckThoracic

Adenocarcinoma, Bronchial Diseases, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT04347161 2026-03-04

iSMART

75 enrolled 10 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Signs and Symptoms, Medication Adherence

NCT04798664 2026-02-25

Comparing Smoking Cessation Interventions Among Underserved Patients Referred for Lung Cancer Screening

3,228 enrolled 41 charts

Lung Neoplasms, Tobacco Use Disorder, Smoking Cessation

NCT03724331 2026-02-24

Understanding the Post-Surgical Non-Small Cell Lung Cancer Patient's Symptom Experience

235 enrolled 17 charts

Carcinoma, Non-Small-Cell Lung, Fatigue, Lung Neoplasms, Motor Activity

NCT03686007 2026-02-20

Multimedia Self-Management Intervention for Lung Cancer Surgery Family Caregivers and Patients

380 enrolled 20 charts

Lung Neoplasms

NCT04738487 2026-02-20

Coformulation of Pembrolizumab/Vibostolimab (MK-7684A) Versus Pembrolizumab (MK-3475) Monotherapy for Programmed Cell Death 1 Ligand 1 (PD-L1) Positive Metastatic Non-Small Cell Lung Cancer (MK-7684A-003, KEYVIBE-003)

Phase 3 Completed

1,264 enrolled 16 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06000683 2026-02-20

Empower-LCS

79 enrolled 20 charts

Lung Neoplasms

NCT02513563 2026-02-19

AZD1775 Plus Carboplatin-Paclitaxel in Squamous Cell Lung Cancer

42 enrolled 12 charts

Phase 1/2 Active not recruiting

Lung Neoplasms

NCT02422381 2026-02-18

MK-3475 and Gemcitabine in Non-Small Cell Lung Cancer (NSCLC)

16 enrolled 12 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04081688 2026-02-05

Atezolizumab and Varlilumab in Combination With Radiation Therapy for NSCLC

Phase 1 Terminated

16 enrolled 9 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04889989 2026-02-04

Microwave Ablation in Chinese Patients With Lung Tumors

Phase NA Terminated

13 enrolled 11 charts

Lung Neoplasms

NCT05061823 2026-02-02

Bintrafusp Alfa Program Rollover Study

Phase 3 Completed

22 enrolled 11 charts

GastrointestinalSarcomaThoracic

Lung Neoplasms, Neoplasms

NCT02408861 2026-01-21

Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Phase 1 Terminated

79 enrolled 24 charts

Anus Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Sarcoma, Kaposi, HIV Infections

NCT03575793 2026-01-20

A Phase I/II Study of Nivolumab, Ipilimumab and Plinabulin in Patients With Recurrent Small Cell Lung Cancer

Phase 1/2 Completed

39 enrolled 18 charts

Lung Neoplasms

NCT04763824 2026-01-14

KANSURVIVE

BreastGastrointestinalGenitourinaryThoracic

15 enrolled 18 charts

Breast Neoplasms, Lung Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms

NCT00596648 2026-01-13

A Study of XL184 (Cabozantinib) With or Without Erlotinib in Subjects With Non-Small Cell Lung Cancer (NSCLC)

Phase 1/2 Completed

92 enrolled 14 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04585815 2026-01-09

Study of Immunotherapy (Sasanlimab) in Combination With Targeted Therapies in People With Advanced Non-small Cell Lung Cancer (NSCLC) (Landscape 1011 Study)

Phase 1/2 Terminated

34 enrolled 44 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT05021133 2026-01-08

Tele-Navigation of Lung Cancer Screening (Tele-Navi LCS)

22 enrolled 6 charts

Phase 1/2 Active not recruiting

Lung Neoplasms

NCT03899792 2026-01-06

LIBRETTO-121

36 enrolled 13 charts 2 FDA

BreastCNSEndocrineGastrointestinalHead & NeckSarcomaThoracic

Thyroid Cancer, Papillary, Breast Neoplasms, Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Endocrine System Diseases, Endocrine Gland Neoplasms, Head and Neck Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Site, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Sarcoma, Thoracic Neoplasms, Thyroid Diseases, Thyroid Neoplasms, Central Nervous System Neoplasms, Myofibromatosis, Carcinoma, Medullary

NCT05524454 2026-01-06

CONFIGURE

BreastGynecologicHead & NeckThoracic

41 enrolled 6 charts

Breast Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Pelvic Neoplasms

NCT02638090 2025-12-22

Pembro and Vorinostat for Patients With Stage IV Non-small Cell Lung Cancer (NSCLC)

Phase 1/2 Active not recruiting

120 enrolled 14 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04905082 2025-12-11

HOPE-Genomics Intervention for the Improvement of Cancer Patient Knowledge of Genomics

BreastGastrointestinalGenitourinaryGynecologicThoracic

465 enrolled 11 charts

Breast Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms

NCT01147965 2025-11-25

QUILT-3.038: Active Immunotherapy CEA Vaccine in Patients With Malignancies Expressing CEA

Phase 1/2 Completed

43 enrolled 15 charts

BreastGastrointestinalGenitourinaryThoracic

Breast Neoplasms, Colonic Neoplasms, Lung Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms

NCT03132532 2025-11-25

Platinum Doublet Chemotherapy and Proton Beam Radiation Therapy in Treating Patients With Stage II-III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery

20 enrolled 20 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT05299606 2025-11-24

POWER Study (Prospective Transbronchial Microwave + Robotic-Assisted Bronchoscopy)

Phase NA Terminated

12 enrolled 14 charts

Phase 3 Active not recruiting

Lung Neoplasms

NCT03703297 2025-11-21

ADRIATIC

730 enrolled 19 charts 1 FDA

Carcinoma, Lung Neoplasms, Small Cell Lung Carcinoma

NCT05824273 2025-11-21

The INSPIRE-Lung Study

512 enrolled 25 charts

Lung Neoplasms

NCT01847209 2025-11-18

Percutaneous Image Guided Video-Assisted Thoracic Surgery (VATS) Resection of Lung Lesions

25 enrolled 5 charts

Lung Neoplasms

NCT03915951 2025-11-17

An Open-label Study of Encorafenib + Binimetinib in Patients With BRAFV600-mutant Non-small Cell Lung Cancer

98 enrolled 18 charts 1 FDA

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasms

NCT04396535 2025-11-17

Docetaxel With or Without Bintrafusp Alfa for the Treatment of Advanced Non-small Cell Lung Cancer

Phase 2 Terminated

10 enrolled 17 charts

Lung Neoplasms

NCT02293954 2025-11-14

Copper Cu 64 Anti-CEA Monoclonal Antibody M5A PET in Diagnosing Patients With CEA Positive Cancer