Clinical Trials

34 enrolled

Lung Neoplasms

NCT06549816 2025-12-15

A Study of SGN-B6A in Chinese Participants With Advanced Solid Tumors

GastrointestinalGynecologicHead & NeckThoracic

6 enrolled

Adenocarcinoma Of Esophagus, Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Ovarian Neoplasms, Colorectal Neoplasms

NCT03177291 2025-12-05

Pirfenidone Combined With Standard First-Line Chemotherapy in Advanced-Stage Lung NSCLC

48 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04885998 2025-09-29

AMG 757 and AMG 404 in Subjects With Small Cell Lung Cancer (SCLC)

23 enrolled 21 charts

Lung Neoplasms, Small Cell Lung Carcinoma

NCT03801902 2025-09-23

Testing the Safety of Adding Either Monalizumab (IPH2201) or Oleclumab (MEDI9447) to Durvalumab (MEDI4736) Plus Standard Radiation Therapy for Locally Advanced Non-small Cell Lung Cancer (NSCLC), ARCHON-1 Trial

26 enrolled 17 charts

Lung Neoplasms

NCT01218854 2025-09-22

A Comparison of Methods for Assisting Needle Angle Selection During Image-guided Tissue Biopsy

GastrointestinalGenitourinaryThoracic

17 enrolled

Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Neoplasms

NCT02185690 2025-08-21

MEK162

13 enrolled 11 charts

Carcinoma, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT02903914 2025-08-05

Arginase Inhibitor INCB001158 as a Single Agent and in Combination With Immune Checkpoint Therapy in Patients With Advanced/Metastatic Solid Tumors

GastrointestinalGenitourinaryHead & NeckOther solid neoplasmThoracic

260 enrolled 52 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Urinary Bladder Neoplasms, Carcinoma, Renal Cell, Head and Neck Neoplasms, Lung Neoplasms, Mesothelioma, Neoplasm Metastasis, Stomach Neoplasms, Colorectal Neoplasms

NCT06048367 2025-08-03

CNSI-Fe(II)

BreastGastrointestinalGynecologicHead & NeckThoracic

19 enrolled 47 charts

Breast Neoplasms, Uterine Cervical Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Thyroid Neoplasms, Vulvar Neoplasms, Colorectal Neoplasms

NCT04051827 2025-07-28

Drug-Drug Interaction Study of TAK-788 and Midazolam in Participants With Advanced Non-small Cell Lung Cancer (NSCLC)

26 enrolled 21 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03199586 2025-07-20

Clinical Trial of Metastasis Inhibitor NP-G2-044 in Patients With Advanced or Metastatic Treatment-Refractory Solid Tumor Malignancies

BreastGastrointestinalGenitourinaryGynecologicThoracic

23 enrolled

Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Liver Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms

NCT03884556 2025-07-02

TTX-030 Single Agent and in Combination With Immunotherapy or Chemotherapy for Patients With Advanced Cancers

GastrointestinalGenitourinaryLymphoidThoracic

56 enrolled 19 charts

Urinary Bladder Neoplasms, Lung Neoplasms, Lymphoma, Neoplasms, Pancreatic Neoplasms

NCT02279433 2025-06-24

A First-in-human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of DS-6051b

EndocrineGastrointestinalNETThoracic

46 enrolled

Lung Neoplasms, Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Neuroendocrine Tumors

NCT02318771 2025-05-15

Radiation Therapy and MK-3475 for Patients With Recurrent/Metastatic Head and Neck Cancer, Renal Cell Cancer, Melanoma, and Lung Cancer

DermatologicGenitourinaryHead & NeckThoracic

41 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Renal Cell, Lung Neoplasms, Melanoma

NCT00838929 2025-05-04

Study of the Combination of Vorinostat and Radiation Therapy for the Treatment of Patients With Brain Metastases

17 enrolled 8 charts

BreastCNSThoracic

Brain Neoplasms, Breast Neoplasms, Lung Neoplasms

NCT04774952 2025-04-15

Dose Escalation of RMC-5552 Monotherapy in Relapsed/Refractory Solid Tumors

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

58 enrolled

Urinary Bladder Neoplasms, Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Uterine Cervical Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Esophageal Diseases, Esophageal Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Diseases, Lung Neoplasms, Melanoma, Neoplasms, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Hereditary Sensory and Autonomic Neuropathies, Ovarian Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Skin Neoplasms, Thoracic Neoplasms, Uterine Neoplasms, Neoplasms, Squamous Cell

NCT06386653 2025-04-09

Molecular Imaging of EpCAM Receptors Using [123I]I-DARPIN-Ec1

10 enrolled

GynecologicThoracic

Lung Neoplasms, Ovarian Neoplasms

NCT03667716 2025-01-17

COM701 (an Inhibitor of PVRIG) in Subjects With Advanced Solid Tumors.

BreastGastrointestinalGynecologicThoracic

121 enrolled

Breast Neoplasms, Colonic Neoplasms, Lung Neoplasms, Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT05712889 2024-11-15

Phase 1 Dose Escalation Study for VIP236 in Patients With Advanced Cancer

BreastGastrointestinalGynecologicThoracic

29 enrolled

Biliary Tract Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Stomach Neoplasms, Endometrial Neoplasms, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT04855929 2024-11-08

ANV419-001

55 enrolled

Disease, Lung Neoplasms, Neoplasms, Recurrence

NCT01766739 2024-10-26

Intra-pleural Administration of GL-ONC1, a Genetically Modified Vaccinia Virus, in Patients With Malignant Pleural Effusion: Primary, Metastases and Mesothelioma

18 enrolled

Lung Neoplasms, Pleural Effusion

NCT04105283 2024-10-15

Tc99m-MAA Bronchial Artery Injection During Bronchial Embolization for Pulmonary Mass Induced Hemoptysis for Dosimetry Planning

8 enrolled

Lung Neoplasms

NCT04713891 2024-09-24

A Study of KF-0210 in Advanced Solid Tumors Patients

GastrointestinalGenitourinaryThoracic

14 enrolled

Esophageal Squamous Cell Carcinoma, Urinary Bladder Neoplasms, Lung Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT02595866 2024-08-09

Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer

DermatologicGastrointestinalLymphoidSarcomaThoracic

58 enrolled 17 charts

Carcinoma, Non-Small-Cell Lung, Carcinoma, Hepatocellular, Lung Neoplasms, Lymphoma, Non-Hodgkin, Melanoma, Neoplasm Metastasis, Neoplasms, Recurrence, Sarcoma, Kaposi, HIV Infections

NCT04479306 2024-06-04

Osimertinib in Combination With Alisertib or Sapanisertib for the Treatment of Osimertinib-Resistant EGFR Mutant Stage IIIB or IV Non-Small Cell Lung Cancer

37 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04881045 2024-04-03

Study to Test the Safety and Tolerability of PF-07257876 in Participants With Selected Advanced Tumors.

GynecologicHead & NeckThoracic

29 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms

NCT03329950 2024-03-28

A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignancies

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidThoracic

132 enrolled

Bile Duct Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Esophageal Neoplasms, Fallopian Tube Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Laryngeal Neoplasms, Liver Neoplasms, Lung Neoplasms, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Melanoma, Mouth Neoplasms, Oropharyngeal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Lymphoma, Large B-Cell, Diffuse, Cholangiocarcinoma, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Hyper-IgM Immunodeficiency Syndrome

NCT03590054 2024-03-22

Abexinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumor Malignancies

DermatologicGenitourinaryHead & NeckThoracic

35 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Ureteral Neoplasms

NCT05231746 2024-03-13

A Study of hSTC810 With Advanced/Metastatic Solid Tumors (STCUBE-001)

GastrointestinalGenitourinaryGynecologicHead & NeckThoracic

47 enrolled

Urinary Bladder Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Colorectal Neoplasms

NCT00019006 2024-03-04

Vaccine Therapy in Treating Patients With Colon, Pancreatic, or Lung Cancer

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Gastrointestinal Neoplasms, Lung Neoplasms, Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Genetic Diseases, Inborn, Small Cell Lung Carcinoma

NCT00020267 2024-03-04

Vaccine Therapy in Treating Patients With Metastatic Cancer

BreastDermatologicGastrointestinalSarcomaThoracic

Uveal Melanoma, Bone Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Eye Neoplasms, Gastrointestinal Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Rectal Neoplasms, Recurrence, Sarcoma, Osteosarcoma, Skin Neoplasms, Colorectal Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Breast Neoplasms, Male, Muscle Neoplasms, Genetic Diseases, Inborn, Histiocytoma, Malignant Fibrous

NCT03454451 2023-12-21

CPI-006 Alone and in Combination With Ciforadenant and With Pembrolizumab for Patients With Advanced Cancers

BreastGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidSarcomaThoracic

117 enrolled

Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Kidney Neoplasms, Lung Neoplasms, Lymphoma, Non-Hodgkin, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Sarcoma, Colorectal Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT05071014 2023-12-20

A Study of Pembrolizumab and Cryoablation in People With Mesothelioma

2 enrolled

Lung Neoplasms

NCT05510674 2023-12-20

Evolution

49 enrolled

Lung Neoplasms

NCT02693080 2023-11-22

CT Perfusion Imaging in Predicting Treatment Response in Patients With Non-small Cell Lung Cancer or Lung Metastases Treated With Stereotactic Ablative Radiation Therapy

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03493789 2023-10-18

Fludeoxyglucose F-18-PET in Planning Lung Cancer Radiation Therapy

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00084799 2023-10-04

Monoclonal Antibody Therapy in Treating Patients With Progressive Small Cell Lung Cancer (SCLC)

10 enrolled 13 charts

Lung Neoplasms, Small Cell Lung Carcinoma

NCT01998529 2023-09-14

Study of Cytoreductive Surgery and Hyperthermic Intrathoracic Pleural Chemotherapy (HITC) With Escalating Doses for Children and Adolescents With Unilateral Pleural Malignancy

7 enrolled

SarcomaThoracic

Lung Neoplasms, Sarcoma

NCT01997190 2023-08-25

MpeTK01

BreastGynecologicOther solid neoplasmThoracic

Breast Neoplasms, Lung Neoplasms, Mesothelioma, Ovarian Neoplasms, Pleural Effusion, Malignant

NCT04131426 2023-08-15

Evaluating the Combined Intervention of Nutritional Supplementation (Remune) and Exercise in Patients With Cancer Cachexia

25 enrolled

Cachexia, Gastrointestinal Neoplasms, Lung Neoplasms, Motor Activity, Neoplasms, Weight Loss

NCT00107250 2023-08-04

AZD2171 + Chemotherapy in Advanced NSCLC, Colorectal Cancer, or Other Cancer Suitable for Treatment With Capecitabine (Non-Small Lung Cancer Patients Closed to Enrollment as 8/9/07)

50 enrolled

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00343408 2023-08-04

AZD2171 and Standard Combination Chemotherapy in Advanced Non-Small Cell Lung Cancer or Colorectal Cancer

31 enrolled

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00471432 2023-08-04

OGX-011 and Docetaxel in Treating Patients With Metastatic or Locally Recurrent Solid Tumors

BreastGenitourinaryGynecologicThoracic

40 enrolled

Carcinoma, Ovarian Epithelial, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Kidney Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Breast Neoplasms, Male

NCT00526461 2023-08-04

Photodynamic Therapy Using HPPH in Treating Patients With Stage 0 Non-Small Cell Lung Cancer

17 enrolled

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04959981 2023-07-25

HERKULES-2

24 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Noonan Syndrome, Thoracic Neoplasms

NCT04452214 2023-07-14

A Study of the Safety and Tolerance of CAN04 and Pembrolizumab in Combination With and Without Carboplatin and Pemetrexed in Subjects With Solid Tumors