Clinical Trials Browser

Brain Neoplasms, Carcinoma, Ependymoma, Histiocytosis, Langerhans-Cell, Medulloblastoma, Neoplasms, Neoplasms, Germ Cell and Embryonal, Neuroblastoma, Pinealoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Rhabdoid Tumor

NCT01356290 2026-02-23

MEMMAT

Phase 2 Recruiting

232 enrolled

CNS

Ependymoma, Medulloblastoma, Recurrence

NCT02875314 2026-02-12

HeadStart4: Newly Diagnosed Children (<10 y/o) With Medulloblastoma and Other CNS Embryonal Tumors

Phase 4 Active not recruiting

250 enrolled

CNS

Medulloblastoma

NCT05535166 2026-02-12

Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma

Phase 2 Recruiting

130 enrolled

CNS

Brain Neoplasms, Medulloblastoma

NCT00336024 2026-01-23

Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk Medulloblastoma

Phase 3 Completed

91 enrolled 24 charts

CNS

Medulloblastoma

NCT05106296 2026-01-09

Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer

Phase 1 Recruiting

37 enrolled

CNS

Brain Neoplasms, Ependymoma, Glioblastoma, Medulloblastoma, Neuroectodermal Tumors, Primitive

NCT04049669 2026-01-08

Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG

Phase 2 Active not recruiting

130 enrolled

CNS

Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Ependymoma, Glioblastoma, Medulloblastoma

NCT02905110 2025-03-25

Methotrexate and Etoposide Infusions Into the Fourth Ventricle in Children with Recurrent Posterior Fossa Brain Tumors

Phase EARLY_PHASE1 Completed

3 enrolled

CNS

Brain Neoplasms, Ependymoma, Medulloblastoma, Rhabdoid Tumor

NCT04521946 2024-10-26

Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer

Phase 1 Withdrawn

CNS

Choroid Plexus Carcinoma, Brain Neoplasms, Ependymoma, Glioma, Medulloblastoma, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor

NCT04501718 2024-10-15

Apatinib Combined with Temozolomide and Etoposide Capsules in the Treatment of Recurrent Medulloblastoma in Children

Phase 2 Recruiting

44 enrolled

CNS

Medulloblastoma

NCT01505569 2024-02-26

Auto Transplant for High Risk or Relapsed Solid or CNS Tumors

Phase NA Completed

44 enrolled

CNSGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Brain Neoplasms, Carcinoma, Renal Cell, Medulloblastoma, Neoplasms, Germ Cell and Embryonal, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Central Nervous System Neoplasms, Hepatoblastoma, Rhabdoid Tumor

NCT00003309 2023-06-22

Combination Chemotherapy Plus Radiation Therapy in Treating Adult Patients With Brain Cancer

Phase 2 Completed

33 enrolled

CNS

Ependymoma, Medulloblastoma, Central Nervous System Neoplasms

NCT02017964 2023-01-09

Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed, Non-metastatic Desmoplastic Medulloblastoma

Phase 2 Completed

26 enrolled 14 charts

CNSDermatologic

Basal Cell Nevus Syndrome, Medulloblastoma

NCT02502708 2020-06-04

Study of the IDO Pathway Inhibitor, Indoximod, and Temozolomide for Pediatric Patients With Progressive Primary Malignant Brain Tumors

Phase 1 Completed

81 enrolled

CNSSarcoma

Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Gliosarcoma

NCT00007813 2020-02-17

Peripheral Stem Cell Transplantation Plus Chemotherapy in Treating Patients With Malignant Solid Tumors

Phase 1 Completed

21 enrolled

CNSGastrointestinalGenitourinaryGynecologicSarcoma

Familial ependymoma, Ovarian Germ Cell Cancer, Testicular Germ Cell Tumor, Astrocytoma, Liver Neoplasms, Medulloblastoma, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Sarcoma, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor, Optic Nerve Glioma

NCT00749723 2018-07-20

HIT-REZ-2005

Phase 2/3 Completed

174 enrolled

CNS

Brain Neoplasms, Ependymoma, Medulloblastoma, Recurrence

NCT01857453 2018-07-05

RSMA2010

Phase 2 Unknown

97 enrolled

CNS

Medulloblastoma

NCT00623077 2017-12-05

MT2004-30: Tomotherapy for Solid Tumors

Phase 1 Terminated

23 enrolled

CNSGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Familial ependymoma, Astrocytoma, Carcinoma, Renal Cell, Carcinoma, Hepatocellular, Kidney Neoplasms, Liver Neoplasms, Medulloblastoma, Wilms Tumor, Retinoblastoma, Sarcoma, Central Nervous System Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor, Optic Nerve Glioma

NCT00003597 2014-07-24

Colony-Stimulating Factors in Treating Children With Recurrent or Refractory Solid Tumors

Phase 1 Completed

16 enrolled

CNSClassical hematologyDermatologicGenitourinaryGynecologicOther solid neoplasmSarcoma

Uveal Melanoma, Astrocytoma, Carcinoma, Renal Cell, Medulloblastoma, Melanoma, Neoplasms, Wilms Tumor, Neuroblastoma, Neutropenia, Retinoblastoma, Osteosarcoma, Testicular Neoplasms, Thrombocytopenia, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma, Gestational Trophoblastic Disease

NCT00006258 2013-07-18

Combination Chemotherapy Followed by Radiation Therapy in Treating Patients With Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Ependymoma

Phase 2 Completed

CNS

Ependymoma, Medulloblastoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive

NCT00007982 2013-02-04

Chemotherapy Plus Peripheral Stem Cell Transplant in Treating Patients With Central Nervous System Cancer

Phase 2 Completed

30 enrolled

CNSHead & NeckLymphoid

Astrocytoma, Brain Neoplasms, Head and Neck Neoplasms, Lymphoma, Medulloblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Esthesioneuroblastoma, Olfactory

NCT00180791 2007-09-18

High Risk Primitive Neuroectodermal (PNET) Brain Tumors in Childhood

Phase 2 Unknown

71 enrolled

CNS

Brain Neoplasms, Medulloblastoma, Neuroectodermal Tumors, Primitive

Clinical Trials

AflacST1502

MEMMAT

HeadStart4: Newly Diagnosed Children (<10 y/o) With Medulloblastoma and Other CNS Embryonal Tumors

Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma

Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk Medulloblastoma

Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer

Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG

Methotrexate and Etoposide Infusions Into the Fourth Ventricle in Children with Recurrent Posterior Fossa Brain Tumors

Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer

Apatinib Combined with Temozolomide and Etoposide Capsules in the Treatment of Recurrent Medulloblastoma in Children

Auto Transplant for High Risk or Relapsed Solid or CNS Tumors

Combination Chemotherapy Plus Radiation Therapy in Treating Adult Patients With Brain Cancer

Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed, Non-metastatic Desmoplastic Medulloblastoma

Study of the IDO Pathway Inhibitor, Indoximod, and Temozolomide for Pediatric Patients With Progressive Primary Malignant Brain Tumors

Peripheral Stem Cell Transplantation Plus Chemotherapy in Treating Patients With Malignant Solid Tumors

HIT-REZ-2005

RSMA2010

MT2004-30: Tomotherapy for Solid Tumors

Colony-Stimulating Factors in Treating Children With Recurrent or Refractory Solid Tumors

Combination Chemotherapy Followed by Radiation Therapy in Treating Patients With Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Ependymoma

Chemotherapy Plus Peripheral Stem Cell Transplant in Treating Patients With Central Nervous System Cancer

High Risk Primitive Neuroectodermal (PNET) Brain Tumors in Childhood