NCT00003789 2013-07-16Melphalan With or Without Tumor Necrosis Factor in Treating Patients With Locally Advanced Melanoma of the Arm or LegNational Cancer Institute (NCI)Phase 3 Completed216 enrolled
NCT00001296 2008-03-04A Randomized Phase III Trial of Hyperthermic Isolated Limb Perfusion With Melphalan, Tumor Necrosis Factor, and Interferon-Gamma in Patients With Locally Advanced Extremity MelanomaNational Institutes of Health Clinical Center (CC)Phase 3 Completed122 enrolled