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Clinical Trials

1 trials

Recent Start date Enrollment

Phase 1/2 × Melanoma × defactinib × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Dermatologic 1 CNS 1

Conditions

Pancreatic Neoplasms 2 Carcinoma, Non-Small-Cell Lung 2 Ovarian Neoplasms 1 Neoplasms 1 Neoplasm Metastasis 1 Mesothelioma 1 Melanoma 1 Glioblastoma 1 Brain Neoplasms 1

Interventions

pembrolizumab 66 Nivolumab 50 Ipilimumab 38 Cyclophosphamide 29 aldesleukin 23 Interleukin-2 22 Temozolomide 17 fludarabine 15 Biopsy 11 trametinib 9 fludarabine phosphate 9 dabrafenib 9 Dacarbazine 8 sargramostim 7 Paclitaxel 7 Cisplatin 7 Bevacizumab 7 lenvatinib 6 cemiplimab 6 binimetinib 6 spartalizumab 5 poly ICLC 5 montanide ISA 51 5 epacadostat 5 Vemurafenib 5 Specimen Handling 5 Radiotherapy 5 Magnetic Resonance Spectroscopy 5 Granulocyte-Macrophage Colony-Stimulating Factor 5 toripalimab 4

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT06194929 2025-12-03

DETERMINE

University of Utah

Phase 1/2 Recruiting

CNSDermatologic

Brain Neoplasms, Melanoma

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