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Phase 2 × Melanoma × olaparib × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Conditions

Ovarian Neoplasms 32 Breast Neoplasms 23 Triple Negative Breast Neoplasms 16 Prostatic Neoplasms 15 Fallopian Tube Neoplasms 11 Neoplasms 8 Pancreatic Neoplasms 6 Glioma 6 Endometrial Neoplasms 6 Carcinoma, Ovarian Epithelial 6 Stomach Neoplasms 5 Small Cell Lung Carcinoma 5 Sarcoma 5 Fanconi Anemia, Complementation Group D1 5 Cholangiocarcinoma 5 Urinary Bladder Neoplasms 4 Lymphoma, Non-Hodgkin 4 Carcinoma, Non-Small-Cell Lung 4 Advanced Breast Cancer 4 Uterine Cervical Neoplasms 3 Squamous Cell Carcinoma of Head and Neck 3 Recurrence 3 Osteosarcoma 3 Neoplasm Metastasis 3 Medulloblastoma 3 Lung Neoplasms 3 Glioblastoma 3 Colorectal Neoplasms 3 Wilms Tumor 2 Uveal Melanoma 2

Interventions

Ipilimumab 93 Nivolumab 88 pembrolizumab 81 aldesleukin 65 Cyclophosphamide 42 Interleukin-2 39 trametinib 29 Temozolomide 28 Dacarbazine 28 fludarabine phosphate 27 dabrafenib 27 incomplete Freund's adjuvant 25 Vemurafenib 24 Bevacizumab 24 sargramostim 22 fludarabine 22 Radiosurgery 20 binimetinib 18 encorafenib 17 Paclitaxel 17 cobimetinib 15 Carboplatin 15 atezolizumab 14 Radiotherapy 14 Sorafenib 12 montanide ISA 51 11 CTLA-4 Antigen 11 Biopsy 11 talimogene laherparepvec 10 MART-1 Antigen 10

Date Range

30 days 90 days 1 year All

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Has results Has announcements

NCT05482074 2024-01-19

Olaparib in Unresectable/Metastatic Melanoma With BRCA1/2

Dana-Farber Cancer Institute

Phase 2 Withdrawn

Uveal Melanoma, Melanoma

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