Prospective Randomized Study of Cell Transfer Therapy for Metastatic Melanoma Using Tumor Infiltrating Lymphocytes Plus IL-2 Following Non-Myeloablative Lymphocyte Depleting Chemo Regimen Alone or in Conjunction With 12Gy Total Body Irradiation (TBI...
Phase 2 Completed
102 enrolled 12 charts
Ipilimumab With or Without Bevacizumab in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery
Phase 2 Completed
169 enrolled 14 charts
Eligibility Screening for the NIH Intramural Research Program Clinical Protocols
Completed
19,522 enrolled
Uprosertib, Dabrafenib, and Trametinib in Treating Patients With Stage IIIC-IV Cancer
Phase 1/2 Completed
27 enrolled 16 charts
Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer
Phase 1 Completed
58 enrolled 17 charts
Retrospective Analysis of a Drug-Metabolizing Genotype in Cancer Patients and Correlation With Pharmacokinetic and Pharmacodynamics Data
Completed
484 enrolled
A Phase I Trial of T Cells Expressing an Anti-GD2 Chimeric Antigen Receptor in Children and Young Adults With GD2+ Solid Tumors
Phase 1 Completed
15 enrolled
flt3L With or Without Vaccine Therapy in Treating Patients With Metastatic Melanoma or Renal Cell Cancer
Phase 2 Completed
Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Metastatic Melanoma
Phase 2 Completed
Vaccine Therapy in Treating Patients With High-Risk Stage III or Completely Resected Metastatic Melanoma
Phase 2 Completed
Vaccine Therapy in Treating Patients With Metastatic Cancer
Phase 1 Completed
A Follow-up Study of Women Evaluated and Treated for Infertility
Completed
12,193 enrolled
Cancer Risk in Carriers of the Gene for Xeroderma Pigmentosum
Completed
301 enrolled
Cabozantinib S-Malate in Treating Younger Patients With Recurrent or Refractory Solid Tumors
Phase 1 Completed
41 enrolled 20 charts
Nivolumab With or Without Ipilimumab in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Sarcomas
Phase 1/2 Completed
140 enrolled 23 charts
Follow-up Protocol for Patients With Cancer/AIDS/Skin Disease
Completed
1,031 enrolled
Collecting Solid Tumor Tissue to Identify New Treatments
Completed
133 enrolled
Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Melanoma
Phase 2 Completed
33 enrolled 21 charts
T Cell Receptor Immunotherapy Targeting MAGE-A3 for Patients With Metastatic Cancer Who Are HLA-DP0401 Positive
Phase 1/2 Completed
21 enrolled 22 charts
A Vaccine (CDX-1401) With or Without a Biologic Drug (CDX-301) for the Treatment of Patients With Stage IIB-IV Melanoma
Phase 2 Completed
60 enrolled 13 charts
T Cell Receptor Immunotherapy Targeting NY-ESO-1 for Patients With NY-ESO-1 Expressing Cancer
Phase 2 Completed
11 enrolled 12 charts
Sun Exposure and Melanoma in Agricultural Workers
Completed
447 enrolled
Sargramostim, Vaccine Therapy, or Sargramostim and Vaccine Therapy in Preventing Disease Recurrence in Patients With Melanoma That Has Been Removed By Surgery
Phase 3 Completed
815 enrolled 10 charts
Family Study of Melanoma in Italy
Completed
1,708 enrolled
The Incidence of Breast and Other Cancers Among Female Flight Attendants
Completed
6,093 enrolled
Mechanism of Action of High-Dose IL-2 (Aldesleukin) in Metastatic Melanoma and Kidney Cancer
Phase 1 Completed
138 enrolled
Gamma-secretase/Notch Signalling Pathway Inhibitor RO4929097 in Combination With Cisplatin, Vinblastine, and Temozolomide in Treating Patients With Recurrent or Metastatic Melanoma
Phase 1/2 Completed
14 enrolled 16 charts
Part 2 of Phase 1 Study of GC1008 to Treat Advanced Melanoma (Part 2 Will Only Accept and Treat Patients With Advanced Malignant Melanoma)
Phase 1 Completed
9 enrolled
Aldesleukin With or Without Ziv-Aflibercept in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery
Phase 2 Completed
84 enrolled 13 charts
Vorinostat in Treating Patients With Metastatic or Unresectable Melanoma
Phase 2 Completed
32 enrolled 11 charts
AZD2171 in Treating Patients With Recurrent or Stage IV Melanoma
Phase 2 Completed
24 enrolled 12 charts
Imatinib Mesylate and Bevacizumab in Treating Patients With Advanced Melanoma or Other Advanced Cancers
Phase 1/2 Completed
40 enrolled 10 charts
VEGF Trap in Treating Patients With Recurrent Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery
Phase 2 Completed
41 enrolled 7 charts
Bevacizumab and Sorafenib in Treating Patients With Unresectable Stage III or Stage IV Malignant Melanoma
Phase 2 Completed
14 enrolled 5 charts
Aldesleukin With or Without Vaccine Therapy in Treating Patients With Locally Advanced or Metastatic Melanoma
Phase 3 Completed
185 enrolled 11 charts
Recombinant Interleukin-15 in Treating Patients With Advanced Melanoma, Kidney Cancer, Non-small Cell Lung Cancer, or Squamous Cell Head and Neck Cancer
Phase 1 Completed
20 enrolled
Microarray Analysis for Human Genetic Disease
Completed
1,500 enrolled
Cyclophosphamide and Fludarabine Followed By Interleukin-2 Gene-Modified Tumor Infiltrating Lymphocytes in Treating Patients With Metastatic Melanoma
Phase 1/2 Completed
33 enrolled
Mel47
Phase 2 Completed
17 enrolled 12 charts
Vaccine Therapy in Treating HLA-A2 Positive Patients With Melanoma
Phase 2 Completed
36 enrolled 7 charts
Lenalidomide (Revlimid) to Treat Advanced Ocular Melanoma
Phase 2 Completed
17 enrolled 11 charts
Bevacizumab With or Without Interferon Alfa in Treating Patients With Metastatic Malignant Melanoma
Phase 2 Completed
57 enrolled 9 charts
Cyclophosphamide, Fludarabine, and Total-Body Irradiation Followed By Cellular Adoptive Immunotherapy, Autologous Stem Cell Transplantation, and Interleukin-2 in Treating Patients With Metastatic Melanoma
Phase 2 Completed
34 enrolled 11 charts
Radiation, Chemotherapy, Vaccine and Anti-MART-1 and Anti-gp100 Cells for Patients With Metastatic Melanoma
Phase 2 Completed
4 enrolled 11 charts
Carboplatin and Paclitaxel With or Without Sorafenib Tosylate in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery
Phase 3 Completed
823 enrolled 9 charts
Chemotherapy Followed by gp100 Lymphocytes and Aldesleukin to Treat Melanoma
Phase 2 Completed
10 enrolled 9 charts
Prospective Randomized Comparative Study of Cell Transfer Therapy Using CD8+-Enriched Short-Term Cultured Anti-Tumor Autologous Lymphocytes Following a Non-Myeloablative Lymphocyte Depleting Chemotherapy Regimen Compared to High-Dose Aldesleukin in M...
Phase 2 Completed
12 enrolled 10 charts
MEK Inhibitor AZD6244 in Treating Patients With Stage III or Stage IV Melanoma
Phase 2 Completed
167 enrolled 6 charts
Biological Therapy in Treating Patients With Metastatic Melanoma or Metastatic Kidney Cancer
Phase 1 Completed
Interleukin-7 and Vaccine Therapy in Treating Patients With Metastatic Melanoma
Phase 1 Completed