Clinical Trials

Melanoma

NCT03420963 2026-03-03

Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors

DermatologicGenitourinaryHead & NeckOther solid neoplasmSarcomaThoracic

12 enrolled

Mesothelioma, Malignant, Bone Neoplasms, Endocrine Gland Neoplasms, Melanoma, Mouth Neoplasms, Pharyngeal Neoplasms, Sarcoma, Skin Neoplasms, Thyroid Neoplasms, Urologic Neoplasms

NCT03716193 2026-02-27

Measurement of the Partial Pressure of Oxygen in Cutaneous Tumors Using Electron Paramagnetic Resonance (EPR) Oximetry

3 enrolled

Melanoma, Skin Neoplasms

NCT04093323 2026-02-25

Polarized Dendritic Cell (aDC1) Based Treatment, Interferon Alpha-2, Rintatolimod, and Celecoxib for the Treatment of HLA-A2+ Refractory Melanoma

1 enrolled

Melanoma

NCT03428581 2026-02-24

Preventing Lymphedema in Axillary Lymph Node Dissection

264 enrolled

BreastDermatologic

Breast Neoplasms, Lymphedema, Melanoma

NCT03865212 2026-01-28

Modified Virus VSV-IFNbetaTYRP1 in Treating Patients With Stage III-IV Melanoma

12 enrolled

Uveal Melanoma, Melanoma

NCT03673332 2026-01-22

EPITOP-01

Phase 4 Terminated

40 enrolled

DermatologicThoracic

Carcinoma, Non-Small-Cell Lung, Melanoma

NCT03595683 2025-12-08

Pembrolizumab and EDP1503 in Advanced Melanoma

8 enrolled 10 charts

Melanoma

NCT05393713 2025-12-03

Intra-Lymphatic STI-3031 Using the Sofusa DoseConnect Device for Treatment of In-Transit Melanoma, The Sofusa-2 Study

3 enrolled

Melanoma

NCT04955743 2025-11-24

Pembrolizumab and Lenvatinib in Patients With Brain Metastases From Melanoma or Renal Cell Carcinoma

CNSDermatologicGenitourinary

18 enrolled

Brain Neoplasms, Carcinoma, Renal Cell, Melanoma

NCT02706353 2025-11-21

APX005M in Combination With Systemic Pembrolizumab in Patients With Metastatic Melanoma

34 enrolled 18 charts

Melanoma

NCT06275854 2025-10-14

YASU Research Registry: For Young Adults With Cancer

BreastDermatologicGastrointestinalLymphoidOther hematologic neoplasmSarcoma

192 enrolled

Breast Neoplasms, Leukemia, Lymphoma, Melanoma, Neoplasms, Neoplasms, Germ Cell and Embryonal, Sarcoma, Colorectal Neoplasms

NCT05388877 2025-08-19

E6201 and Dabrafenib for the Treatment of Central Nervous System Metastases From BRAF V600 Mutated Metastatic Melanoma

Brain Neoplasms, Melanoma

NCT04941430 2025-08-12

7T MRI Scan for the Early Detection of Melanoma Brain Metastases

2 enrolled

Brain Neoplasms, Melanoma

NCT03698162 2025-08-05

Precise DCE-MRI in Diagnosing Participants With Recurrent High Grade Glioma or Melanoma Brain Metastases

15 enrolled

Brain Neoplasms, Melanoma

NCT04904185 2025-07-25

ImmPACT Expanded Multiple Antigen Specific Endogenously Derived T Cells (MASE-T) to Patients With Metastatic Melanoma

8 enrolled 8 charts

Melanoma

NCT05714553 2025-07-18

NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

19 enrolled

Squamous Cell Carcinoma of Head and Neck, Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Esophageal Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Stomach Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT04116320 2025-07-14

AM-003

BreastDermatologicGastrointestinalGenitourinaryGynecologicThoracic

5 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Melanoma, Ovarian Neoplasms, Stomach Neoplasms, Carcinoma, Merkel Cell, Neoplasms, Squamous Cell, Small Cell Lung Carcinoma

NCT03991741 2025-07-03

Adoptive Cell Transfer of Autologous Tumor Infiltrating Lymphocytes and High-Dose Interleukin 2 in Select Solid Tumors

3 enrolled 9 charts

DermatologicHead & Neck

Head and Neck Neoplasms, Melanoma, Neoplasm Metastasis

NCT05388851 2025-06-22

Education for Prevention of Melanoma in Hispanic Populations

145 enrolled

Melanoma

NCT03325101 2025-06-12

Dendritic Cell Therapy With Pembrolizumab for Metastatic or Unresectable Melanoma

7 enrolled 11 charts

BreastCNSDermatologicGastrointestinalGenitourinaryThoracic

Melanoma

NCT04588246 2025-06-06

Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery

Phase 3 Terminated

19 enrolled 19 charts

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Gastrointestinal Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Small Cell Lung Carcinoma

NCT00716560 2025-05-06

Nausea and Vomiting In Patients Receiving Consecutive Days of Cisplatin

8 enrolled

Melanoma, Nausea

NCT05819827 2025-04-27

Associations Between Chemotherapy-Induced Nausea in Patients With Genitourinary, Sarcoma or Melanoma Cancers and Changes in Gut Microbiome: Potential for Precision Therapeutics

DermatologicGenitourinarySarcoma

Urinary Bladder Neoplasms, Melanoma, Prostatic Neoplasms, Sarcoma, Testicular Neoplasms

NCT05695898 2025-03-26

XmAb23104 (PD1 X ICOS) and XmAb22841 (CTLA-4 X LAG3) in Treating Melanoma Prior Immune Checkpoint Inhibitor Therapy

6 enrolled

Melanoma

NCT04901988 2025-02-27

DETECTION

Phase 2/3 Terminated

8 enrolled

Melanoma

NCT00560118 2025-02-14

MGFOT1

12 enrolled

Melanoma

NCT03991130 2025-02-06

High Dose IL-2 in Combination With Anti-PD-1 to Overcome Anti-PD-1 Resistance in Metastatic Melanoma and Renal Cell Carcinoma

DermatologicGenitourinary

6 enrolled

Carcinoma, Renal Cell, Melanoma, Neoplasm Metastasis

NCT04967196 2024-12-10

Ipilimumab and Nivolumab for the Treatment of Stage III-IV Unresectable Metastatic Melanoma

6 enrolled

Melanoma

NCT03950635 2024-12-04

Dietary Intervention in Patients with a History of Melanoma

Melanoma

NCT04375527 2024-12-04

Binimetinib and Nivolumab for the Treatment of Locally Advanced Unresectable or Metastatic BRAF V600 Wildtype Melanoma

3 enrolled

Melanoma

NCT04310397 2024-10-30

Dabrafenib, Trametinib, and Spartalizumab for the Treatment of BRAF V600E or V600K Mutation Positive Stage IIIB/C/D Melanoma

4 enrolled 8 charts

Melanoma

NCT03476174 2024-10-02

Anti-PD-1 Antibody With HD IL-2 in Metastatic Melanoma

1 enrolled 9 charts

Melanoma

NCT05200143 2024-09-19

Study of Ipilimumab, Nivolumab, and Cabozantinib in Patients With Cutaneous Melanoma

4 enrolled 11 charts

Melanoma

NCT03370861 2024-09-05

MINING

54 enrolled

Autoimmune Diseases, Carcinoma, Basal Cell, Melanoma, Skin Neoplasms, Carcinoma, Merkel Cell

NCT02714374 2024-08-06

GL-ONC1 Administered Intravenously Prior to Surgery to Patients With Solid Organ Cancers

DermatologicGastrointestinalOther solid neoplasmThoracic

5 enrolled

Gallbladder Neoplasms, Melanoma, Mesothelioma, Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT03233828 2024-07-24

IL-2

Phase 3 Terminated

1 enrolled 3 charts

Melanoma

NCT04655157 2024-05-23

QUAD01

2 enrolled 12 charts

Melanoma

NCT02621515 2024-05-06

CA209-322

7 enrolled

Brain Neoplasms, Melanoma

NCT02700763 2024-05-06

[18F]Dabrafenib Molecular Imaging in Melanoma Brain Metastasis

1 enrolled

Brain Neoplasms, Melanoma

NCT02922283 2024-05-06

IL2 Imaging in Metastatic Melanoma

19 enrolled

Melanoma

NCT02978443 2024-04-04

A Biomarker Study in Advanced Mucosal or Acral Lentiginous Melanoma Receiving Nivolumab in Combination With Ipilimumab

14 enrolled 12 charts

Melanoma

NCT04899921 2024-03-26

Troriluzole or Placebo Plus Ipi Plus Nivo in Mel Brain Mets

1 enrolled

Melanoma

NCT01769222 2024-01-24

Ipilimumab and Local Radiation for Selected Solid Tumors

DermatologicGastrointestinalLymphoidOther hematologic neoplasm

3 enrolled 5 charts

Burkitt Lymphoma, Colonic Neoplasms, Immunoblastic Lymphadenopathy, Leukemia, Hairy Cell, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Melanoma, Mycosis Fungoides, Rectal Neoplasms, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, T-Cell, Peripheral, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Extranodal NK-T-Cell, Intraocular Lymphoma

NCT03709771 2024-01-12

Novel Mechanisms and Predictors of VEGF Receptor Inhibitor- or Immune Checkpoint Inhibitor-Associated Hypertension and Cardiovascular Disease

DermatologicGenitourinary

2 enrolled 6 charts

Carcinoma, Renal Cell, Hypertension, Melanoma, Neoplasms

NCT04187872 2023-12-27

TORCH

CNSDermatologicGastrointestinalGenitourinaryGynecologicThoracic

10 enrolled

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Melanoma, Stomach Neoplasms, Carcinoma, Merkel Cell, Small Cell Lung Carcinoma

NCT04663126 2023-12-13

Tilmanocept

Phase EARLY_PHASE1 Terminated

5 enrolled

Phase EARLY_PHASE1 Terminated

Melanoma

NCT02382549 2023-12-12

Mel61

8 enrolled

Melanoma

NCT02425306 2023-10-30

Mel63; CHAMP

48 enrolled 13 charts