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Active not recruiting × Meningeal Carcinomatosis × GDC-0084 × Clear all

Phase

Status

Active not recruiting 1

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Conditions

Meningeal Carcinomatosis 1 Brain Neoplasms 1

Interventions

toripalimab 1 lorlatinib 1 adavosertib 1 Radiotherapy 1 Radiation 1 Pemetrexed 1 Immunotherapy, Adoptive 1 GDC-0084 1

Date Range

30 days 90 days 1 year All

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Has results Has announcements

NCT04192981 2025-04-17

GDC-0084 With Radiation Therapy for People With PIK3CA-Mutated Solid Tumor Brain Metastases or Leptomeningeal Metastases

Memorial Sloan Kettering Cancer Center

Phase 1 Active not recruiting

Brain Neoplasms, Meningeal Carcinomatosis

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