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Meningeal Carcinomatosis × tucatinib × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Conditions

Breast Neoplasms 30 Colorectal Neoplasms 7 Brain Neoplasms 6 Neoplasms 5 HER2-positive Breast Cancer 5 Stomach Neoplasms 4 Triple Negative Breast Neoplasms 3 Neoplasm Metastasis 3 Meningeal Neoplasms 3 Carcinoma, Non-Small-Cell Lung 3 Rectal Neoplasms 2 Multiple Myeloma 2 Lymphoma, Non-Hodgkin 2 Colonic Neoplasms 2 Adenocarcinoma Of Esophagus 2 Pathologic Complete Response 1 Ovarian Neoplasms 1 Neoplasms by Site 1 Metastatic Breast Cancer With a Isolated Brain Progression 1 Meningeal Carcinomatosis 1 Lung Neoplasms 1 Hemangiosarcoma 1 HER2-positive Metastatic Breast Cancer 1 HER2-positive Gastric Cancer 1 Gallbladder Neoplasms 1 Esophageal Neoplasms 1 Cholangiocarcinoma 1 Central Nervous System Diseases 1 Breast Diseases 1 Anatomic Stage II Breast Cancer AJCC v8 1

Interventions

Pemetrexed 20 Bevacizumab 9 Radiotherapy 8 osimertinib 6 Spinal Puncture 6 Magnetic Resonance Spectroscopy 6 Specimen Handling 5 aflutinib 4 Trastuzumab 4 Topotecan 4 Temozolomide 4 Radiotherapy, Intensity-Modulated 4 Methotrexate 4 Dexamethasone 3 trastuzumab deruxtecan 2 pembrolizumab 2 paclitaxel-Angiopep-2 conjugate 2 merphos 2 lorlatinib 2 aumolertinib 2 WP 744 2 Vitamin B 12 2 Rituximab 2 Radiation 2 Folic Acid 2 Drug Therapy 2 Cytarabine 2 Cyclophosphamide 2 Capecitabine 2 Busulfan 2

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT05800275 2025-11-18

ETIC-LM

UNICANCER

Phase 2 Recruiting

Meningeal Neoplasms, Meningeal Carcinomatosis

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