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Meningeal Carcinomatosis

NCT07098806 2025-08-01

CA2024-LM-001

Meningeal Neoplasms, Neoplasm Metastasis, Neoplasms, Neoplasms by Site, Nervous System Diseases, Nervous System Neoplasms, Pathologic Processes, Central Nervous System Neoplasms, Meningeal Carcinomatosis

NCT00527410 2025-05-30

LMD

Phase 1 Terminated

9 enrolled

CNS

Meningeal Carcinomatosis

NCT05034497 2025-03-26

ReSPECT-LM

Phase 1 Active not recruiting

18 enrolled

CNS

Meningeal Carcinomatosis

NCT05146219 2024-12-30

Study of TY-9591 in Patients With a Lung Cancer With Brain or Leptomeningeal Metastases With EGFR Mutation

Phase 2 Completed

29 enrolled

CNS

Brain Neoplasms, Meningeal Carcinomatosis

NCT05414123 2023-10-16

FORESEE

Terminated

40 enrolled

BreastCNSThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Meningeal Neoplasms, Meningeal Carcinomatosis

NCT03613181 2023-04-24

ANGLeD

Phase 3 Unknown

150 enrolled

BreastCNS

Brain Neoplasms, Breast Neoplasms, Meningeal Neoplasms, Meningeal Carcinomatosis

NCT04315246 2022-07-15

177Lu-DTPA-Omburtamab Radioimmunotherapy for Leptomeningeal Metastasis From Solid Tumors (Breast, NSCLC, Malignant Melanoma)

Phase 1/2 Withdrawn

CNS

Meningeal Carcinomatosis

NCT02228369 2021-01-05

BLOOM

Phase 1 Completed

108 enrolled

CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Meningeal Carcinomatosis

NCT02755987 2016-06-07

Expanded Access to ANG1005 for Individual Patients

No longer available

CNS

Astrocytoma, Oligodendroglioma, Meningeal Carcinomatosis

NCT00854867 2014-02-24

Study to Demonstrate the Safety of WBR Administered at the Same Time as Intrathecal Liposomal Cytarabine (DepoCyte®) Versus Intrathecal Liposomal Cytarabine (DepoCyte®) Administered After WBR for the Treatment of Solid Tumour Neoplastic Meningitis in Patients With or Without Brain Metastasis.

Phase 1 Completed

18 enrolled

CNS

Brain Neoplasms, Meningeal Carcinomatosis

Clinical Trials

Zorifertinib With Osimertinib for NSCLC With Meningeal Progression

CA2024-LM-001

LMD

ReSPECT-LM

Study of TY-9591 in Patients With a Lung Cancer With Brain or Leptomeningeal Metastases With EGFR Mutation

FORESEE

ANGLeD

177Lu-DTPA-Omburtamab Radioimmunotherapy for Leptomeningeal Metastasis From Solid Tumors (Breast, NSCLC, Malignant Melanoma)

BLOOM

Expanded Access to ANG1005 for Individual Patients

Study to Demonstrate the Safety of WBR Administered at the Same Time as Intrathecal Liposomal Cytarabine (DepoCyte®) Versus Intrathecal Liposomal Cytarabine (DepoCyte®) Administered After WBR for the Treatment of Solid Tumour Neoplastic Meningitis in Patients With or Without Brain Metastasis.